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Exotic Animal Formulary5

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Tobramycin

1 g/20 g

methylmethacrylate 41

10% in calcium sulfate

pellets 99

Place in bone after surgical debridement of

jaw abscess

Biodegradable implants for treatment of

osteomyelitis

Trimethoprim/sulfa 15 mg/kg PO q12h 41

30 mg/kg PO, SC, IM

q12h 41,112

May cause tissue necrosis when given

SC 112

15-30 mg/kg PO q12-

24h 112

30-48 mg/kg SC

q12h 112

Tylosin

10 mg/kg PO, SC, IM

q12-24h 112

Vancomycin 50 mg/kg IV q8h 100 PD

10 mg vancomycin and

50 mg DL-lactide-coglycolide

copolymer 41

Osteomyelitis; effective locally for 56 days

a

There is a potential for antibiotic-induced enterotoxemia following administration of some antimicrobial

agents (see Table 10.15). Appetite and fecal character must be monitored closely during and following

therapy.

b

The use of fluoroquinolones in food-producing animals is strictly prohibited in the United States. Do not

use these drugs in rabbits that may be consumed by humans.

Table 10-2

Antifungal Agents Used in Rabbits. a

Agent Dosage Comments

Albaconazole 5 mg/kg PO q24h 98 Cryptococcal meningitis

50 mg/kg PO

q24h 18

Disseminated Scedosporium prolificans

Amphotericin B — Severe fungal infections; use in

combination with fluconazole; 41

potentially nephrotoxic and

hepatotoxic

Desoxycholate form

1 mg/kg IV

q24h 41,112,121

Liposomal form 5 mg/kg IV q24h 110 Invasive aspergillosis

Clotrimazole (Lotrimin,

Bayer)

Topical 41

Localized dermatophytosis

713

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