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Exotic Animal Formulary5

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half-life and mean residence time rapid and

similar in both spp.

5.5 mg/kg IM

q24h × 3 or 7

days 599

Budgerigars/some renal changes at 3 days;

birds had tubular necrosis at 7 days

Ibuprofen — Avoid in Gyps vultures 165

5-10 mg/kg PO

q8-12h 212

Psittacines/use pediatric suspension for small birds

Ketoprofen — Avoid in Gyps vultures, mortalities reported at

clinical doses;261,544 Cape Griffon vultures

1 mg/kg IM

q24h × 1-

10 days 38,76 Raptors

administered 5 mg/kg PO died within 48 hr 546

1-5 mg/kg IM

q12h 648

2.5 mg/kg IM

q24h × 3 or 7

days 599

Raptors

Budgerigars/low frequency of glomerular

congestion, degeneration/dilation of tubules

occurred at 3-7 day treatment

Meloxicam — No reported mortalities in over 700 cases of 60

species of birds, including Gyps vultures, 165,786,787

but few studies to date evaluating renal effects

of higher doses; 190,524b,744 the combination of

avian bornavirus challenge and meloxicam

treatment resulted in severe disease and death

in cockatiels, whereas challenge alone or

meloxicam treatment alone were not lethal

within the duration of this study 352,353

0.1 mg/kg IM

q24h × 3 or 7

days 599

0.5 mg/kg PO

q12h × 14

days 524b

Budgerigars/mild glomerular congestion and

tubular degeneration at 3 and 7 days

African grey parrots/PD; mild to no hematological

or biochemical changes, and no histologic

lesions in 9 of 10 birds after 14 days of

treatment

0.5 mg/kg IV 32 Ostriches, pigeons/PK; variable distribution,

ostrich had more rapid (0.5 hr) than other

species studied

0.5 mg/kg PO,

IV 433

Red-tailed hawks, great horned owls/PK;

significant differences in pharmacokinetics

between species strongly discourages

extrapolation between species; hawks had

353

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