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Exotic Animal Formulary5

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Table 12-3

Chemical Restraint/Anesthetic Agents Used in Miniature Pigs. a

Agent Dosage Comments

Acepromazine 0.1-0.45 mg/kg IM 3 Tranquilization; slow onset of action;

inconsistent results

0.2-1.1 mg/kg IM 5 Higher doses reportedly produce more

profound tranquilization

Acepromazine (A)/

ketamine (K)

(A) 0.5-1.1 mg/kg

IM, followed in

15 min by (K)

15-33 mg/kg IM 3

Atipamezole

Atropine

(A) 1.1 mg/kg+(K)

33 mg/kg IM,

SC 29

For IM dose, see

comments

0.02-0.05 mg/kg SC,

IM, IV 29

Reverses detomidine and dexmedetomidine,

and potentially other α 2 -adrenergic

agonists; actual volume is same as volume

used for detomidine (1 mg/mL) or

dexmedetomidine (0.5 mg/mL)

Anesthesia adjunct; increases heart rate,

decreases GI and respiratory secretions

Azaperone (Stresnil,

Schering-Plough)

— See also ketamine for combinations

0.25-0.5 mg/kg IM 4 Relaxation, sedation, without ataxia up to

0.25-2 mg/kg IM 24 0.5 mg/kg dose

2 mg/kg IM 4 Moderate sedation; doses exceeding 2 mg/kg

likely to produce negative side effects such

2-8 mg/kg IM,

as hypotension, bradycardia, and

SC 9,24,29

decreased cardiac output and

contractility 24

5-8 mg/kg IM 3

Azaperone (Az)/midazolam

(Mi)/± atropine (At)

(Az) 4 mg/kg+(Mi)

0.5 mg/kg±(At)

0.04 mg/kg IM 3 Moderate to deep sedation; no analgesia

Butorphanol — See detomidine, dexmedetomidine, ketamine,

tiletamine/zolazepam, xylazine for

combinations; see Table 12-4 for analgesic

doses

Detomidine (Dormosedan,

Zoetis)

— Detomidine combinations follow

805

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