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Exotic Animal Formulary5

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10-40 mg/kg SC

q12h 84

Mice

10-40 mg/kg SC 70 Chinchillas/PD; no analgesic

effects; side effects at >40 mg/kg;

single-dose study

Table 9-5

Cardiovascular Agents Used in Rodents.

Agent Dosage Comments

Atenolol 0.2-2 mg/kg PO q24h 52 Most species/beta-blocker; hypertension

and tachyarrhythmias

2-10 mg/kg IV, IP q24h 84 Mice

Atropine 0.05-0.5 mg/kg SC, IM 2,52 All species/preanesthetic, cardiac problems

0.1-0.2 mg/kg SC IM 84 Guinea pigs, chinchillas

Up to 10 mg/kg IM, SC, IV

q20min 41,84

All species/organophosphate toxicity

Benazepril 0.05–0.1 mg/kg PO q24h 52,84 Most species/ACE inhibitor; heart failure,

hypertension, and chronic renal failure

0.125-0.25 mg/kg PO

q24h 29,30

Carvedilol 1-11 mg/kg PO q24h 84 Hamsters/beta-blocker

2-30 mg/kg PO q24h 84 Rats/beta-blocker

Digoxin 0.005-0.01 mg/kg PO q12-

24h 29-31

0.05-0.1 mg/kg PO q12-

24h 74,84

Most species

Hamsters/dilated cardiomyopathy

Diltiazem 0.5-1 mg/kg PO q12-24h 31,52 Most species/Ca channel blocker;

hypertension and hypertrophic

cardiomyopathy

Dopamine 0.08 mg/kg IV prn 64 Guinea pigs/hypotension, especially

anesthetic related

Enalapril 0.5-1 mg/kg PO q24h 30,31 ACE inhibitor; heart failure

Epinephrine

(adrenaline)

0.003-0.1 mg/kg IV prn 31 Guinea pigs/cardiac arrest

0.01 mg/kg IV 84 Most species

0.1 mg/kg IV 90 Most species

680

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