Exotic Animal Formulary5

0.2 mg/kg IV 72 Squirrel monkeys
Bupivacaine (0.5%)
0.25 mg/kg IM,
IV 72
1.2 mg/kg epidural
as two
0.6 mg/kg
doses at 2 min,
then 20 min 86
2 mg/kg maximum
perineurally 25
Macaques
Rhesus macaques/epidural analgesia
Macaques/local anesthetic
Buprenorphine — Opioid agonist-antagonist; analgesia 35
0.005-0.01 mg/kg
SC, 38 IM, IV q6-
12h 29
Rhesus macaques, marmosets
0.005-0.01 mg/kg
SC, IM, IV q6-
12h 35
0.005-0.03 mg/kg
IM, IV q6-12h 41
0.01 mg/kg IM, IV
q6-8h 66,72
0.01 mg/kg IM
q12h 16
0.01-0.02 mg/kg
SC, IM, IV q8-
12h 91
Common marmosets
Macaques/PK; not to exceed 0.3 mg/animal
IM q8h in chimpanzees 72
Rhesus macaques/postoperative analgesia
Prosimians
0.01-0.02 mg/kg
IM q12h 59
0.01-0.05 mg/kg
IM, SC q8-12h 44
0.03 mg/kg IM
q12h 46,66 or IV
bolus 46
Sustained-release:
0.2 mg/kg SC
once 66
Macaques/PK
Macaques/single injection; plasma
concentrations 0.1 ng/mL
Butorphanol — In primates, butorphanol behaves more as
an agonist with intermediate efficacy;
may cause profound respiratory
depression—reverse with naloxone 41,59,67
0.01-0.02 mg/kg Common marmosets
841