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Exotic Animal Formulary5

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lifetime treatment; higher dosage may shrink

prostate within 12-48 hr which may improve

urine flow in cases of urethral obstruction;

must be prepared in aliquots and frozen

(although the effects of freezing on drug

efficacy are questionable) until used; very

expensive

1 mg IM q60-

75d 11

3 month

depot

Adrenal disease

Lupron, Depot 30 day

(TAP)

Lupron, Depot 4

month (TAP)

100-150 µg/kg

IM q4-

8wk 1,70

250 µg/kg

IM q4-8wk 26

250 µg/kg IM 59

2 mg/kg SC,

IM q16wk 52

Melatonin 0.5-

1 mg/animal

PO q24h 61

prn

5.4 mg implant

SC 52

Symptomatic treatment of hyperadrenocorticism;

may not affect tumor growth

Should last 6-12 mo

Mitotane (o,p′-DDD)

(Lysodren, Bristol-

Myers)

— Hyperadrenocorticism; variable results and not a

reliable alternative to adrenalectomy or other

drugs mentioned above; results have been

largely unsatisfactory and, therefore, use is

not recommended

Trilostane (Vetoryl,

Dechra)

2 mg/kg PO

q12h 52

May be useful for treating pituitary-dependent

hyperadrenocorticism or adrenal dependent

hyperadrenocorticism; reduces synthesis of

adrenal androgens

Table 11-7

Miscellaneous Agents Used in Ferrets. a

Agent Dosage Comments

Activated charcoal 1-3 g/kg PO 52 Orally administered adsorbent for

gastrointestinal tract toxins/drug

overdoses

776

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