Exotic Animal Formulary5

therapy; little activity when used as
a single agent 41,73
10 mg/kg PO
q24h 58
100 mg/kg PO
q12h×21 days 41
Dermatophytosis
Less effective than fluconazole for
coccidioidal meningitis
100 mg/kg PO q12-
24h 41
100 mg/kg PO q24h
in combination
with
amphotericin B
0.4 mg/kg IV
q24h 73
Invasive aspergillosis
Voriconazole — The short terminal elimination half-life
of less than 1 hr in the rabbit
indicates that the efficacy of
voriconazole is less than optimal in
this species; 117 however, voriconazole
is effective as a topical antifungal
ophthalmic preparation in the rabbit
(see Table 10.6)
a
Antifungal protocols using amphotericin B administered intravenously or itraconazole, fluconazole, or
ketoconazole administered orally alone or in combination for deep mycotic infections have been based
on those used successfully in the dog and may be adequate treatment options in the rabbit; however,
this hypothesis requires confirmation and validation. 14 Certain antifungal protocols have not caused death
in rabbit models, even when given for extended periods. 18,41,107,109,110,121
Table 10-3
Antiparasitic Agents Used in Rabbits.
Agent Dosage Comments
Albendazole
7.5-20 mg/kg PO Potential treatment for
q24h 41 ×3-
encephalitozoonosis; use
14 days 41,112 cautiously, deaths have been
reported 52
Amprolium (9.6%)
0.5 mL/pint drinking
water×10 days 112
0.625 mL/pint
drinking
water×21 days 41
Coccidiosis
Carbaryl powder 5% Topically q7d 41 Ectoparasites; use sparingly
715