Exotic Animal Formulary5

concentrations 76
Flunixin
meglumine
— Potential nephrotoxicity; histologic glomerular
changes were demonstrated in bobwhite quail
given doses as low as 0.1 mg/kg (severity of
lesions was directly correlated to
dose); 83 IM administration caused muscle
necrosis in mallard ducks 105
1.1 mg/kg IV 14 Chickens, ducks, turkeys, and chickens had long
half-life, but ostrich t 1/2 =10 min
3 mg/kg IM 74 Chickens/PD; arthritis behaviors reduced 1 hr
after treatment
5 mg/kg IM 105 Mallard ducks/PD; reduced thromboxane activity
for 12 hr; muscle necrosis at injection site
5 mg/kg IV 176 Chickens/PK; t 1/2 =3 hr
1.3 mg/kg IV RLP
once 137b
Chickens/pododermatitis; regional limb perfusion
(RLP) into medial metatarsal vein with a
tourniquet placed proximal to hock joint for
15 min 137b
Ketoprofen
1 mg/kg IM q24h×
1-10 days 14-16,69 Waterfowl/arthritis
2 mg/kg PO, SC, IM,
IV 59,60
2-5 mg/kg PO, IM, IV
q12-24h 69
3 mg/kg IM
q24h×5 days 115
Japanese quail/PK, PD; poor bioavailability and
rapid clearance after PO or IM administration
Eider ducks/high mortality in male ducks may be
due to high bupivacaine dose or cumulative
toxicity of bupivacaine and ketoprofen
Chickens/no adverse clinical signs; normal
creatinine, uric acid, ALT, AST
5 mg/kg IM q12h 104,105 Mallard ducks/PD; inhibited thromboxane for
approximately 12 hr
5-10 mg/kg IM, IV 27,69 Waterfowl
12 mg/kg IM 74 Chickens/reduced arthritic pain behaviors for
12 hr
Meloxicam 0.5 mg/kg IV 14,15 Chickens, ducks, turkeys/PK; variable
distribution
1 mg/kg PO, IM
q12h 173
Chicken
1 mg/kg PO once 146 Chickens/PK; t 1/2 =2.8 hr; drug detected in egg
white up to 4 days and egg yolk up to 8 days
after dosing
1-1.5 mg/kg PO q12- Chicken
578