Exotic Animal Formulary5

combinations
Tylosin
2-10 mg/kg PO,
SC q12h 90
10 mg/kg PO, SC
q12h 84,90,115
10 mg/kg PO
q24h×5 days 113
Hamsters, gerbils/use with caution
Chinchillas, guinea pigs, mice,
rats/toxicity reported in guinea pigs
Rats
0.5 mg/mL Gerbils, hamsters, mice, rats/PD in rats; 18
(500 mg/L) toxicity in hamsters reported 3
drinking
water 15
Vancomycin
20 mg/kg PO
q24h 46
Tyzzer’s disease
a
Oral antibiotic treatment can result in enteritis and antibiotic-associated clostridial enterotoxemia,
especially when antibiotics with a primary Gram-positive spectrum are given. Chinchillas, guinea pigs,
and hamsters are most susceptible. Also, direct toxicity due to streptomycin and dihydrostreptomycin
occurs in gerbils, guinea pigs, hamsters, and mice. Procaine, included in some penicillin preparations,
can be toxic to mice. Guinea pigs and chinchillas are highly susceptible to the ototoxic effects of
chloramphenicol and aminoglycosides at dosages above those recommended clinically. Antibiotics
implicated in antibiotic-associated clostridial enterotoxemia following oral administration include: 49,97
• Chinchillas: penicillins (including ampicillin, amoxicillin), bacitracin, cephalosporins,
clindamycin, erythromycin, lincomycin.
• Guinea pigs: penicillins (including ampicillin, amoxicillin), cefazolin, clindamycin,
erythromycin, lincomycin, dihydrostreptomycin, streptomycin, bacitracin,
chlortetracycline, oxytetracycline, tetracycline, tylosin.
• Hamsters: penicillins (including ampicillin, amoxicillin), bacitracin, cephalosporins,
clindamycin, erythromycin, lincomycin, vancomycin, dihydrostreptomycin,
streptomycin, tylosin.
Table 9-2
Antiparasitic Agents Used in Rodents.
Agent Dosage Comments
Albendazole 5 mg/kg PO q12h 10 Guinea pigs
25 mg/kg PO
q12h×2 days 90
Amitraz 1.4 mL/L (0.007%)
topical q7-14d×3
treatments 2,84,90
Chinchillas/giardiasis
Gerbils, hamsters/demodecosis; apply
with cottonball, brush; use with
caution; not recommended in
young
0.3% solution Guinea pigs/mites
665