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Exotic Animal Formulary5

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1 Vincristine 0.025 mg/kg IV

3 Cyclophosphamide 10 mg/kg PO, SC

2 8 Vincristine 0.025 mg/kg IV

3 15 Vincristine 0.025 mg/kg IV

4 22 Vincristine 0.025 mg/kg IV

24 Cyclophosphamide 10 mg/kg PO, SC

7 46 Cyclophosphamide 10 mg/kg PO, SC

9 63 Prednisone Gradually decrease

dose to 0 over the

next 4 wk

Protocol II b,52

Week Agent Dosage

1 Vincristine 0.025 mg/kg IV

L-asparaginase

Prednisone

400 U/kg IP

1 mg/kg PO q24h and continued throughout therapy

2 Cyclophosphamide 10 mg/kg SC

3 Doxorubicin 1 mg/kg IV

4-6 As weeks 1-3 above,

but discontinue

L-asparaginase

8 Vincristine 0.025 mg/kg IV

10 Cyclophosphamide 10 mg/kg SC

12 Vincristine 0.025 mg/kg IV

14 Methotrexate 0.5 mg/kg IV

Protocol III 47

Week Agent Dosage

1 L-asparaginase 10,000 U/m 2 SC

Cytoxin

Prednisone

250 mg/m 2 PO, SC (in 50 mL/kg of NaCl SC)

colspan="2"2 mg/kg PO daily

for 7 days, then q48h

throughout therapy

2 L-asparaginase 10,000 U/m 2 SC

Perform CBC c

3 L-asparaginase 10,000 U/m 2 SC

790

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