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Exotic Animal Formulary5

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Table 5-27

Quick Reference to Abnormalities of the Standard Avian Hematology Profile. 268

Parameter Increases Decreases

PCV/RBC

Heterophils

Dehydration

Regenerative anemia

• Increased total protein • Polychromasia (10%), reticulocytes,

Erythrocytosis (polycythemia) immature RBC

• Normal or low total

• Hemorrhagic: Trauma, parasites,

protein

coagulopathies, ulcerated neoplasms,

• Primary rare

gastrointestinal ulcers

• Secondary to respiratory • Hemolytic: Septicemia, hemoparasites,

or cardiovascular disease toxicities, immune-mediated

• Presence of Heinz bodies,

agglutination of RBC

Nonregenerative anemia

• Hypoplastic: Inflammatory infectious,

myelosuppresive drugs, iron

deficiency, food restriction, folic acid

deficiency

Inflammatory processes

• Bacterial (including

Mycobacterium) and fungal

infections

• Excess corticosteroids

○ Endogenous

production

○ Exogenous

administration

Birds with a high heterophil:

lymphocyte ratio may

mount a greater leukocytic

response

Infection

• Bacterial and viral (i.e., PBFD)

Poor sample preparation, collection, and

storage

Lymphocytes

Monocytes

Eosinophils

Chronic antigenic stimulation

Neoplasia: lymphocytic

leukemia

Stress response (acute)

Granulomatous and/or chronic

inflammation (e.g.,

bacterial, fungal, parasitic)

Neoplasia

Gastrointestinal parasitism

Type IV hypersensitivity

reactions

Stress response (chronic)

Immunosuppresive drugs

Viral infection

Endotoxemia/septicemia

Corticosteroids

Stress response (chronic)

Basophils Early inflammatory responses —

445

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