Monograph on the Potential Human Reproductive and ... - OEHHA

BISPHENOL A
Table 52
In Vitro Estrogenicity Testing of Bisphenol A
Endpoint Molar potency relative to 17b-estradiol Reference
Binding assays
Frog liver cytosol binding [1.4 x 10 -3 ] Lutz and Kloas (1999)
Carp liver cytosol binding [1.3 x 10 -3 ] Segner et al. (2003)
Rainbow trout ER binding 5.8 x 10 -5
Olsen et al. (2005)
Rainbow trout ER binding 2.1 x10 -3
Matthews et al. (2000)
Anole ER binding 1.3 x 10 -3
Matthews et al. (2000)
Chicken ER binding 4.4 x 10 -4
Matthews et al. (2000)
Mouse ERa binding 8.6 x 10 -5
Matthews et al. (2000)
Mouse uterine cytosol binding [1.2 x 10 -4 ] Matthews et al. (2001)
Rabbit uterine ER binding [1.3 x 10 -5 ] Andersen et al. (1999a)
Rat uterine cytosol binding B5 x 10 -4
Krishnan et al. (1993)
Rat uterine cytosol binding 8 x 10 -5
Blair et al. (2000)
Rat uterine cytosol binding 1–2 x 10 -4
Kim et al. (2001a)
Rat ERa binding [2.5 x 10 -4 ] Strunck et al. (2000)
ER binding in rat lactotroph 1–10 x 10 -5
Chun and Gorski (2000)
Rat ERa binding 5 x 10 -4
Kuiper et al. (1997)
Rat ERb binding 3.3 x 10 -4
Kuiper et al. (1997)
Rat uterine ERa and b binding 6.2 x 10 -5
Washington et al. (2001)
Rat uterine Type II estrogen-binding site 4 x 10 -3
Washington et al. (2001)
ER binding in MCF-7 lysates 1 x10 -2
Dodge et al. (1996)
Human ERa binding 4 x 10 -4
Bolger et al. (1998)
Human ERa binding 1 x10 -4
Kuiper et al. (1998)
Human ERb binding 1 x10 -4
Kuiper et al. (1998)
Human ER binding 5.6 x 10 -4
Perez et al. (1998)
Human ER binding [1.3 x 10 -4 ] Andersen et al. (1999a)
ER binding in ECC-1 cells 3 x 10 -3
Bergeron et al. (1999)
Human ERa binding 8 x 10 -5
Matthews et al. (2000)
Human ERa binding [2.5 x 10 -3 diethylstilbestrol] Nakagawa and Suzuki (2001)
Human ERa binding 7.3 x 10 -4
Routledge et al. (2000)
Human ERb binding 7.5 x 10 -3
Routledge et al. (2000)
Human ER binding [7.1 x10 -5 ] Sheeler et al. (2000)
Human ERa binding [8 x 10 -5 ] Matthews et al. (2001)
Human ERb binding [3.8 x 10 -3 ] Matthews et al. (2001)
Human ERa binding 5 x 10 -2
Paris et al. (2002)
Human ERb binding 4 x 10 -2
Paris et al. (2002)
Human ER binding [3 x 10 -4 ] Stroheker et al. (2004)
Human ERa binding [2.4 x 10 -4 ] Seidlová-Wuttke et al. (2005)
Human ERb binding [2.8 x 10 -2 ] Seidlová-Wuttke et al. (2004)
Human ERa binding [1.1 x10 -4 ] Takemura et al. (2005)
Human ERb binding [4.4 x 10 -4 ] Takemura et al. (2005)
Human ER binding 3.15 x 10 -3
Olsen et al. (2005)
ERa binding [9.4 x 10 -4 ] Takayanagi et al. (2006)
ERb binding [9.6 x 10 -4 Recombinant yeast reporter systems
] Takayanagi et al. (2006)
Human ER activation 5 x 10 -5
Coldham et al. (1997)
Human ER activation 6.7 x 10 -5
Gaido et al. (1997)
Human ER activation [2.5 x 10 -5 ] Harris et al. (1997)
Human ER activation [4–8 x 10 -5 ] Andersen et al. (1999a)
Human ER activation [3.9 x 10 -5 ] Sheeler et al. (2000)
Human ER activation B1 x10 -4
Sohoni and Sumpter (1998)
Human ER activation 3.7 x 10 -5
Metcalfe et al. (2001)
ERa activation 6.2 x 10 -5
Silva et al. (2002)
ERa activation [1 x10 -4 ] Nishihara et al. (2000)
ERa activation [B1 x10 -4 ] Beresford et al. (2000)
Human ERa [3.3 x 10 -5 ] Rajapakse et al. (2001)
Human ERa, no microsomes [5.5 x 10 -5 ] Elsby et al. (2001)
Human ERa, human liver microsomes [6.6 x 10 -6 ] Elsby et al. (2001)
ER activation B10 -5
Chen et al. (2002)
Human ER activation [8.1 x10 -5 ] Segner et al. (2003)
Human ER activation 9 x 10 -5
Li et al. (2004)
ERa activation [4 x 10 -5 ] Singleton et al. (2006)
Human ERa, with denatured rat S9 [2.4 x 10 -6 ] Yoshihara et al. (2004)
Human ERa, with active rat S9 [9.2 x 10 -6 ] Yoshihara et al. (2004)
Human ERa, with denatured mouse S9 [3.0 x 10 -6 ] Yoshihara et al. (2004)
Human ERa, with active mouse S9 [7.8 x 10 -6 ] Yoshihara et al. (2004)
Birth Defects Research (Part B) 83:157–395, 2008
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