Monograph on the Potential Human Reproductive and ... - OEHHA
Monograph on the Potential Human Reproductive and ... - OEHHA
Monograph on the Potential Human Reproductive and ... - OEHHA
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Populati<strong>on</strong><br />
Bisphenol A<br />
µg/kg bw/day<br />
3<br />
Assumpti<strong>on</strong>s References<br />
Infant Breast-fed 0.2.–.1* 0.2.assumes.body.weight.of.6.1.kg.<strong>and</strong>.breast.milk.intake.<br />
of. 1060. ml/day. with. 0.97. µg/L. bisphenol.A. [maximum.<br />
c<strong>on</strong>centrati<strong>on</strong>.of.bisphenol.A.detected.in.Japanese.breast.<br />
milk.samples.(28)](25)<br />
1.assumes.body.weight.of.4.5.kg.<strong>and</strong>.breast.milk.intake.<br />
of.700.ml/day.with.6.3.µg/L.free.bisphenol.A.[maximum.<br />
c<strong>on</strong>centrati<strong>on</strong>.of.free.bisphenol.A.detected.in.U.S..breast.<br />
milk.samples.(5)](2)<br />
6.–.12.m<strong>on</strong>ths 1.65.–.13* 1.65.assumes.body.weight.of.8.8.kg.with.(1).7.µg/L.bisphenol.A/day.<br />
from. formula. intake. of. 700. ml/day. with.<br />
10.µg/L.(0.8.µg/kg.bw/day);.<strong>and</strong>.(2).7.6.µg/kg.bisphenol.<br />
A/day.from.ingesti<strong>on</strong>.of.0.38.kg.canned.food/day.with.20.<br />
µg/kg.(~0.85.µg/kg.bw/day)..0.8.+.0.85.=.1.65.(26)<br />
13.assumes.body.weight.of.7.8.kg,.formula.intake.of.920.<br />
ml/day,.<strong>and</strong>.food.c<strong>on</strong>sumpti<strong>on</strong>.of.0.407.kg/day.with.(1).50.<br />
µg/L. bisphenol.A. migrating. into. formula. from. polycarb<strong>on</strong>ate.bottles.(5.9.µg/kg.bw/day);.(2).12.4.µg.bisphenol.<br />
A/day.ingested.from.powdered.infant.formula.packed.in.<br />
food.cans.with.epoxy.linings.(1.6.µg/kg.bw/day).[0.124.<br />
kg.powder/day.(<strong>the</strong>.amount.of.powder.required.to.rec<strong>on</strong>stitute.a.volume.of.formula.of.920.ml/day).c<strong>on</strong>taining.12.4.<br />
µg.bisphenol.(100.µg.bisphenol.A/kg.powder)];.(3).40.7.<br />
µg.bisphenol.A/day.ingested.from.canned.food.(5.2.µg/kg.<br />
bw/day).[0.407.kg.food/day.c<strong>on</strong>taining.40.7.µg.bisphenol.<br />
A.(100.µg.bisphenol.A/kg.food)];.<strong>and</strong>.(4).2.04.µg.bisphenol.A/day.migrati<strong>on</strong>.from.polycarb<strong>on</strong>ate.tableware.(0.26,.<br />
or.~.0.3.µg/kg.bw/day.)[0.407.kg.food/day.c<strong>on</strong>taining.2.04.<br />
µg.bisphenol.A.(5.µg.bisphenol.A/kg.food)].5.9.+.1.6.+.5.2<br />
.+.0.3.=.13.0.µg/kg.bw/day.(25)<br />
Child 1.5.–.6.years 0.043.–.14.7 0.043.is.<strong>the</strong>.mean.(range:.0.018.–.0.071.µg/kg.bw/day).based.<br />
<strong>on</strong>.individual.body.weight.<strong>and</strong>.measured.c<strong>on</strong>centrati<strong>on</strong>s.of.<br />
bisphenol.in.indoor.<strong>and</strong>.outdoor.air,.dust,.soil,.<strong>and</strong>.liquid.<br />
<strong>and</strong>.solid.food.from.day.care.<strong>and</strong>.home.<strong>and</strong>.<strong>the</strong>.assumpti<strong>on</strong>.<br />
of.100%.absorpti<strong>on</strong>.(29)<br />
14.7. assumes. body. weight. of. 14.5. kg. <strong>and</strong>. c<strong>on</strong>sumpti<strong>on</strong>.<br />
of.2.kg.canned.food/day.with.(1).200.µg.bisphenol.A/day.<br />
ingested.from.canned.food.(~14.µg/kg.bw/day).[2.kg.food/<br />
day.c<strong>on</strong>taining.200.µg.bisphenol.A.(100.µg.bisphenol.A/<br />
kg.food)];.<strong>and</strong>.(2).10.µg.bisphenol.A/day.migrati<strong>on</strong>.from.<br />
polycarb<strong>on</strong>ate.tableware.(~.0.7.µg/kg.bw/day).[2.kg.food/<br />
day.c<strong>on</strong>taining.10.µg.bisphenol.A.(5.µg.bisphenol.A/kg.<br />
food)].14.+.0.7.=.14.7(27)<br />
(c<strong>on</strong>tinued <strong>on</strong> next page)<br />
(2, 25)<br />
(24 – 27)<br />
(1, 25 – 27,<br />
29, 30)<br />
nTp brief
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