Monograph on the Potential Human Reproductive and ... - OEHHA

212 CHAPIN ET AL.
Table 52
Continued
Endpoint Molar potency relative to 17b-estradiol Reference
Human ERa, with denatured monkey S9 [2.4 x 10 -6 ] Yoshihara et al. (2004)
Human ERa, with active monkey S9 [6.0 x 10 -6 ] Yoshihara et al. (2004)
Human ERa, with denatured human S9 [2.2 x 10 -6 ] Yoshihara et al. (2004)
Human ERa, with active human S9 [4.6 x 10 -6 ] Yoshihara et al. (2004)
Human ERa activity [2.3 x 10 -5 ] Terasaki et al. (2005)
Medaka ERa activity [3.3 x 10 -4 ] Terasaki et al. (2005)
‘‘Estrogenic activity’’ 3.4 x 10 -5
Kawagoshi et al. (2003)
ERa activation [2.3 x 10 -4 ] Singleton et al. (2006)
Fish ERa activation 4.1 x10 -4
Fu et al. (2007)
Fish ERb2 activation 3.2 x 10 -5
Other cell-based recombinant reporter systems
Fu et al. (2007)
ER activation in trout gonad cell line 5.4 x 10 -3
Ackerman et al. (2002)
Mouse ERa in HeLa cells [o1 x10 -5 ] Ranhotra and Teng (2005)
Mouse ERb in HeLa cells [B1 x10 -2 ] Ranhotra and Teng, 2005
HepG2 cells, human ERa [3.0 x 10 -3 ] Snyder et al. (2000)
HepG2 cells, human ERb [1.1 x10 -2 ] Snyder et al. (2000)
Rat ERa in HeLa cells [1.6 x 10 -7 ] Yamasaki et al. (2002b)
ER activation in HeLa cells [8.8 x 10 -4 ] Takahashi et al. (2004)
ERa activation in HeLa cells [2.5 x 10 -2 ] Hiroi et al. (1999)
ERb activation in HeLa cells [2.3 x 10 -2 ] Hiroi et al. (1999)
ERa activation in HeLa cells [6.1 x10 -1 ] Vivacqua et al. (2003)
ERb activation in HeLa cells [5.6 x 10 -1 ] Vivacqua et al. (2003)
ERa activation in HeLa cells [7.7 x 10 -1 ] Recchia et al. (2004)
ERb activation in HeLa cells [1.2] Recchia et al. (2004)
ERa activation in T47D cells [6.2–7.9 x 10 -1 ] Recchia et al. (2004)
Proliferation in T47D cells [6.6 x 10 -1 ] Recchia et al. (2004)
Human ER in hepatoma cells [3 x 10 -2 ] Gould et al. (1998)
Human ERa, human embryonal kidney [4.8 x 10 -3 ] Kurosawa et al. (2002)
Human ERb, human embryonal kidney [4.6 x 10 -3 ] Kurosawa et al. (2002)
Human ERa, endometrial carcinoma [5.4 x 10 -3 ] Kurosawa et al. (2002)
Human ERb, endometrial carcinoma [4.9 x 10 -3 ] Kurosawa et al. (2002)
Human ERa, osteosarcoma [7.3 x 10 -3 ] Kurosawa et al. (2002)
Human ERb, osteosarcoma [7.7 x 10 -3 ] Kurosawa et al. (2002)
Human ERa, human hepatoma cells [2.7 x 10 -1 ] Gaido et al. (2000)
Human ERb, human hepatoma cells [1.8 x 10 -1 ] Gaido et al. (2000)
Human ERa, 239HEK cells 2 x 10 -4 diethylstilbestrol Lemmen et al. (2004)
Human ERb, 239HEK cells 7 x 10 -4 diethylstilbestrol Lemmen et al. (2004)
Human ERa, endometrial carcinoma [6.1 x10 -3 MCF-7 cells
] Singleton et al. (2006)
G6PD activity [1 x10 -1 ] Kim et al. (2003a)
Expression of proteins [1 x10 -3 ] Perez et al. (1998)
Progesterone receptor mRNA Not increased at 10 -6 M a
Diel et al. (2002)
Androgen receptor mRNA Not decreased at 10 -6 M a
Diel et al. (2002)
Progesterone receptor B2 x 10 -4
Krishnan et al. (1993)
ER binding, serum-free 3.3 x 10 -4
Samuelsen et al. (2001)
ER binding, 100% human serum 1.7 x 10 -4
Samuelsen et al. (2001)
ER binding 3.2 x 10 -3
Olsen et al. (2003)
ER activation [1.4 x 10 -5 ] Kitamura et al. (2005)
ERa expression [7.5 x 10 -5 ] Matthews et al. (2001)
ERb expression [1.8 x 10 -4 ] Matthews et al. (2001)
ERa activation [4.7–6.9 x 10 -1 ] Vivacqua et al. (2003)
ERa activation [5.5–6.7 x 10 -1 ] Recchia et al. (2004)
pS2 induction [1.8 x 10 -6 ] Leffers et al. (2001)
ER production [7 x 10 -8 ] Olsen et al. (2003)
Progesterone receptor production [6.8 x 10 -8 ] Olsen et al. (2003)
pS2 production [10 -7 ] Olsen et al. (2003)
pS2 mRNA [1.1] Vivacqua et al. (2003)
pS2 mRNA [8.9 x 10 -1 ] Recchia et al. (2004)
Cathepsin D mRNA [8.2 x 10 -1 ] Recchia et al. (2004)
Transcription of human telomerase reverse transcriptase [B10 -2 ] Takahashi et al. (2004)
Proliferation [3.8 x 10 -4 ] Krishnan et al. (1993)
Proliferation 1 x10 -3
Brotons et al. (1995)
Proliferation 1 x10 -4
Soto et al. (1997)
Proliferation [B1 x10 -3 ] Dodge et al. (1996)
Proliferation [1 x10 -4 ] Perez et al. (1998)
Birth Defects Research (Part B) 83:157–395, 2008