ON TESTIS AND EPlDlDYMlS OF RATS - Pondicherry University ...

Table 23. Effect of co-administration of TCDD and vitamin E on the DNA, RNA and
protein contents in testis
TCDD and vitamin E
Control Ing+20mg 10ng+20mg 100ng+20mg
DNA 10.62 t 2.1 1 11.31 f 2.48 10.48 * 1.96 12.1 1 * 2.08
RNA 5.46 i 1.91 6.07 + 1.34 6.12 f 1.20 5.69 i 1.07
Protein 8.76 i 0.13 9.1 1 i 1.23 9.41 t 1.40 8.97 i 0.10
Nucleic acids and protein contents are expressed in mg/ g tissue wet weight
The data are expressed as mean * SD for six animals! dose
Table 24a. Effect of co-administration of TCDD and viranlir~ E on the productio~~ ot'
superoxide anion in the c ~de homogenate, mitochondria1 and microsomerich
fractions of rat testis
TCDD and vitamin E
Control lng+20mg lOng+20mg 100ng+20mg
Crude homogenate 3.76 f 0.12 3.79 i 0.18 3.80 f 0.40 3.79 k 0.27
Mitochondria1 fractions 2.13 i 0.19 2.21 i 0.12 2.19 f 0.21 2.20 i 0.17
Microsome-rich
fractions 1.61 i 0.31 1.62 t 0.27 1.68 i 0.12 1.67 i 0.13
'l'hc data are cxpresscd in nniold cninl~ng pn)tcin
The data are expressed as mean f SD for six animals! dose