ON TESTIS AND EPlDlDYMlS OF RATS - Pondicherry University ...

The weight of the venlral proshte showcd a siynilicunt reduction in the 'I'C1)U
treated rats as compared to the corresponding groups of control animals (Table la).
The weight of the ventral prostate when expressed relative to the body weight also
decreased significantly in the rats treated with TCDD as compared to the
corresponding groups of control animals (Table I b).
The weight of the kidney did not show any significant change in the TCDDtreated
rats as compared to the corresponding groups of control animals (Table la).
The weight of the kidney when expressed relative to the body weight did not decrease
in the rats treated with TCDD as compared to the corresponding groups of control
animals (Table I b).
4.1.2 Effect of TCDD on daily sperm production
Administration of TCDD decreased the daily sperm production in a dosedependent
manner with respect to the corresponding group of control animals
(Table 2).
4.1.3 Effect of TCDD on epididymal sperm viability, motility and counts
The epididymal sperm viability did not show any significant change in the
'I'CDD treated rats as compared to the corresponding groups of control animals
(Table 2). Administration of TCDD decreased epididymal sperm motility in a dosedependent
manner as compared to the corresponding group of control animals
(Table 2). The epididymal sperm counts decreased significantly in a dose dependent
manner in the TCDD treated rats as compared to the corresponding group of control
animals (Table 2).
4.1.4 Effect of TCDD on seminiferous tubular and lumen diameter
The diameter of the seminiferous tubules was noted to be decreased
significantly in the rats after administration of TCDD with respect to the
corresponding group of control animals (Table 3). The lumen diameter of the