ON TESTIS AND EPlDlDYMlS OF RATS - Pondicherry University ...

Table 13. Effect of TCDD on the antioxidant enzymes and lipid peroxidation in the
epididymal sperm of adult rats
TCDDI Kg body weight
Control I ng 10 ng I00 ng
Superoxide dismutase'
(mg protein) 22.405 1.43 20.30i2.85' 18.50i 1.51. 16.90k 1.57'
(mg DNA) 18.08+ 0.61 13.64+ 1.14' 12.48i 0.72* 11.385 1.22*
catalaseb
(ing protein) 2.49f 0.13 2.33 i 0.15' 2.305 0.14' 2.03 i0.13'
(mg DNA) 2.01 i 0.05 1.45 i 0.06. 1.44 + 0.08* 1.35 + 0.05'
Glutathione reductase'
(mg protein) 40.00* 2.17 31.20f 2.41. 28.20i 2.49* 27.10f 1.57'
(mg DNA) 32.41 f 0.86 19.46i 0.53. 20.l8i 0.83' 18.07i 0.76*
Glutathione peroxidase'
(mg protein) 71.20i 3.87 64.50i 4.88' 56.605 4.41. 48,OOi 3.97.
(mg DNA) 57.58 i 1.52 40.17 i 1.05' 38.24 i 0.88. 31.94 + 1.79.
Lipid peroxidatton'
(trig protein)
2.17 i 0.20 4.24 i0.418 4.80f 0.38' 6.08+ 0.20'
(mg DNA) 1.75 + 0.82 2.W+ 0.13. 3.24i 0.08' 4.05i 0.12.
nlnol/ tninl mg protein or DNA
pmoll minl rng protein or DNA
moll mg protein or DNA
The data are expressed as meaniSD for six animals! dose
*p