ON TESTIS AND EPlDlDYMlS OF RATS - Pondicherry University ...

Table 30. Effect of co-administration of TCDD and vitamin E on the antioxidant
enzymes and lipid peroxidation in the epididylnal sperm oradult rats
TCDD and vitamin E
Control 1ng+20mg 10ng+20mg 100ng+20mg
Superoxide disrnutase'
(mg protein) 19.84 f 0.89 19.93 f 1.36 20.16 f 1.57 19.81 -t 0.42
(mg DNA) 16.84 5 0.64 17.01 f 0.76 17.01 f 0.77 17.04 & 0.89
catalaseb
(mg protein) 2.12i 0.08 2.13* 0.10 2.151 0.12 2.12f 0.12
(mg DNA) 1.80 f 0.03 1.82 i 0.03 1.81 * 0.03 1-82 2 0.04
Glutathione ductase'
(mg protein) 34.03 i 1.45 33.80f 1.61 34.36 * 1.94 33.54 +- 2.38
(mg DNA) 28.87* 0.51 28.85 f 0.67 29.01 f 0.45 28.76& 0.96
Glutathione peroxidase'
(mg protein) 58.40 f 2.58 58.70 * 2.85 58.96 i 3.19 58.06 + 3.48
(mg DNA) 49.53i 0.85 50.12* 1.24 49.80f 1.13 49.92i 0.98
Lipid peroxidation'
(mg protein) 2.22* 0.16 2.19i 0.16 2.20f 0.19 2.19* 0.18
(mg DNA) 1.88iO.09 1.87f0.07 1.8620.12 1.87+0.06
nmold mid mg protein or DNA
moV mid mg protein or DNA
pnol rnalondialdehyde produced/ mg protein or DNA
The data are expressed as mean* SD for six animals1 dose