ON TESTIS AND EPlDlDYMlS OF RATS - Pondicherry University ...

4.2.11.1 Effect of co-administration of TCDD on the production of rcvctive
oxygen rpeciea In the epididymal sperm
Co-administration of TCDD along with vitamin E did not show any
significant change in the production of superoxide anion, nitric oxide and hydrogen
peroxide in the epididymal sperm of adult rats as compared to the corresponding
groups of control animals (Table 28).
4.2.11.2 Effect of co-administration of TCDD and vitamin E on the levels of
antioxidants in the epididymal sperm
Co-administration of TCDD and vitamin E did not show any significant
change in the levels of reduced glutathione and a-tocopherol in the epididymal sperm
of adult rats as compared to the corresponding groups of control animals (Table 29).
4.2.11.3 Effeet of eo-administration of TCDD and vitamin E on the antioxidant
enzymes and lipid peroxidation in the epididymal sperm
The activities of superoxide dismutase, catalase, glutathione reductase and
glutathione peroxidase remained unchanged in the epididymal sperm of rats treated
with TCDD and vitamin E as compared to the corresponding groups of control
animals (Table 30). The levels of lipid peroxidation also remained unchanged in the
rpididymal sperm of the animals administered with TCDD and vitamin E as
compared to the corresponding groups of control animals (Table 30).
4.2.11.4 EfTect of co-administration of TCDD and vitamin E on the production
of reactive oxygen spccics in the euput, corpus and eaudn cpididyntides
Co-administration of TCDD and vitamin E did not show any significant
change in the production of superoxide anion, nitric oxide and hydrogen peroxide in
all the regions of the epididymis of adult rats as compared to the corresponding
groups of control animals (Table 31).