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ON TESTIS AND EPlDlDYMlS OF RATS - Pondicherry University ...

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Table 33a. Effect of co-administration of TCDD and vitamin E on tlic antioxidant<br />

cnzymcs and lipid pcroxidation in the caput cpididy~iiis<br />

TCDD and vitamin E<br />

Superoxide dismutasea 33.82 i 2.35 33.47 f 1.58 33.66 f 2.39 33.84 * 1.78<br />

catalaseb 2.56i0.17 2.51 i 0.10 2.52f 0.18 2.545 0.15<br />

Glutathione reductase' 43.46 f 2.82 42.84 f 1.68 43.23 * 2.96 43.49 12.84<br />

Glutathione peroxidase'64.49 f 4.32 63.53 i 3.09 63.91 k 4.25 64.1 1 f 4.22<br />

Lipid peroxidatione 2.50 i 0.1 l 2.35 * 0.20 2.30 i 0.14 2.35 f 0.21<br />

'nmold min/ mg protein; pnold minl rng protein<br />

' pmole malondialdehyde producedl mg protein<br />

The data arc expressed as me.aniSD for six animals/ dose<br />

Table 33b. Effect of co-administration of TCDD and vitamin E on the antioxidant<br />

enzymes and lipid peroxidation in the corpus epididymis<br />

TCDD and vitamin E<br />

Control 1ng+20rng IOng+20mg 100ng+20mg<br />

Superoxide dismutasc' 36.39 * 1.49 37.1 1 f 2.48 36.91 i 3.48 37.03 _+ 2.32<br />

Catalascb 3.49f 0.18 3.51 i0.17 3.47i0.27 3.45i 0.15<br />

Glutathione reductasec 32.80 * 1.53 33.20 f 1.66 32.78 It 2.73 23.63 5 1.49<br />

Glutathione peroxidasec62.36 f 3.74 62.85 f 2.98 62.24 i 4.20 62.14 f 3.52<br />

Lipid peroxidation' 2.46 f 0.30 2.49 i 0.12 2.60 i 0.29 2.55 + 0.23<br />

'nmold mint rng protein; wold minl mg protein<br />

'wnole malondialdehydc produced1 mg protein<br />

The data arc expressed as rneaniSD for six animals/ dose

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