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Pandemic Influenza Plan - Questar III

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Section 7: Antiviral Medication Procurement, Distribution, and Use<br />

susceptibility of the pandemic strain, and on when a vaccine becomes<br />

available.<br />

• In conjunction with CDC authorize the use of antivirals to treat and<br />

control the spread of disease from individuals and small clusters, if cases<br />

of novel influenza should occur in the US.<br />

• In conjunction with CDC authorize the tracing of and use of antivirals to<br />

prophylax close contacts of persons with novel influenza.<br />

• As the pandemic becomes more widespread it will no longer be practical<br />

or useful to prophylax against outbreaks.<br />

• Monitor the amount of people that receive antivirals for prophylaxis to<br />

preserve and extend supplies available to treat those persons at the highest<br />

risk of serious morbidity and death.<br />

• Assist with the acquisition, distribution, and administration of antivirals to<br />

identified priority groups.<br />

• Implement mass distribution of antivirals if needed.<br />

Local Health Departments:<br />

• In conjunction with NYSDOH, CDC, and health care partners administer<br />

antivirals to control the spread of disease in small cluster outbreaks or<br />

outbreaks in contained settings.<br />

• Trace and prophylax close contacts of confirmed cases if authorized to do<br />

so by CDC and NYSDOH.<br />

• Assist with the distribution and administration of antivirals to identified<br />

and confirmed priority groups.<br />

• Implement mass distribution of antivirals if needed.<br />

Healthcare Partners:<br />

• With increasing disease activity base treatment decisions on:<br />

o Laboratory confirmation of infection with a pandemic subtype,<br />

o Detection of influenza A by rapid antigen test, or<br />

o Epidemiologic and clinical characteristics.<br />

• Initiate treatment before laboratory confirmation is obtained.<br />

• Continue treatment awaiting confirmatory tests.<br />

• Target prophylaxis to priority groups.<br />

• Use PEP to control small well-defined disease clusters and to protect<br />

individuals with a known exposure to a pandemic virus, such as household<br />

contacts.<br />

• PEP may be used to protect those prioritized during the period between<br />

vaccination and the development of immunity.<br />

• If possible reserve the use of antivirals for prophylaxis only during period<br />

of peak viral circulation if that information is available.<br />

February 7, 2006 7-13

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