PCT/2000/51 - World Intellectual Property Organization

51/2000
19092 PCT Gazette - Section I - Gazette du PCT 21 Dec/déc 2000
TJ TM); EP (AT BE CH CY DE DK ES FI FR
GB GR IE IT LU MC NL PT SE); OA (BF BJ
CF CG CI CM GA GN GW ML MR NE SN
TD TG).
(51) 7 C07C 255/00
(11) WO 00/76959
(21) PCT/US00/14504
(13) A2
(22) 25 May/mai 2000 (25.05.2000)
(25) en (26) en
(30) 60/139,420 16 Jun/juin 1999
(16.06.1999)
US
(43) 21 Dec/déc 2000 (21.12.2000)
(54) INTERMEDIATES FOR THE
PREPARATION OF N-[2-(CAR-
BOXYMETHOXY) ETHYL]-N-(CAR-
BOXYMETHYL) GLYCINE
INTERMEDIAIRES POUR LA PRE-
PARATION DE N-[2-(CARBOXYME-
THOXY) ETHYL]-N-(CARBOXYME-
THYL) GLYCINE
(71) THE DOW CHEMICAL COMPANY
[US/US]; 2030 Dow Center, Midland, MI
48674 (US).
(72) ATHEY, Phillip, S.; 119 White Oak, Lake
Jackson, TX 77566 (US). WILSON, David,
A.; 204 Tearose, Lake Jackson, TX 77566
(US).
(74) KARADZIC, Dragan, J.; Intellectual Property,
B-1211, 2301 N. Brazosport Boulevard,
Freeport, TX 77541 (US).
(81) BR CA JP MX.
(84) EP (AT BE CH CY DE DK ES FI FR GB GR
IE IT LU MC NL PT SE).
(51) 7 C07C 303/28, 309/66, 227/32, 229/18,
231/18, 233/51, 235/16
(11) WO 00/76960 (13) A1
(21) PCT/EP00/05460
(22) 13 Jun/juin 2000 (13.06.2000)
(25) en (26) en
(30) MI99A001330 15 Jun/juin 1999 IT
(15.06.1999)
(43) 21 Dec/déc 2000 (21.12.2000)
(54) PROCESS FOR THE PREPARA-
TION OF OPTICALLY ACTIVE
N-ACYL DERIVATIVES OF METHYL
N-(2,6-DIMETHYLPHENYL)-D-ALAN-
INATE
PROCESSUS DE PREPARATION DE
DERIVES OPTIQUEMENT ACTIFS DE
N-ACYLES DE METHYLE N- (2,6-DI-
METHYLEPHENYLE) -D-ALANINATE
(71) ISAGRO S.P.A. [IT/IT]; Via Felice Casati,
20, I-20124 Milano (IT).
(for all designated States except / pour tous
les États désignés sauf US)
(72, 75) ZANARDI, Giampaolo [IT/IT]; Viale
Roma, 19, I-28100 Novara (IT). CON-
FALONIERI, Giovanni [IT/IT]; Via
Caronni, 15, I-20052 Monza (IT).
(74) DE GREGORI, Antonella et al. / etc.; Ing.
Barzanò & Zanardo, Milano S.p.A., Via Borgonuovo,
10, I-20121 Milan (IT).
(81) AE AL AM AT AU AZ BA BB BG BR BY
CA CH CN CR CU CZ DE DK DM DZ EE
ES FI GB GD GE GH GM HR HU ID IL IN
IS JP KE KG KP KR KZ LC LK LR LS LT
LU LV MA MD MG MK MN MW MX MZ
NO NZ PL PT RO RU SD SE SG SI SK SL
TJ TM TR TT TZ UA UG US UZ VN YU ZA
ZW.
(84) AP (GH GM KE LS MW MZ SD SL SZ TZ
UG ZW); EA (AM AZ BY KG KZ MD RU
TJ TM); EP (AT BE CH CY DE DK ES FI FR
GB GR IE IT LU MC NL PT SE); OA (BF BJ
CF CG CI CM GA GN GW ML MR NE SN
TD TG).
Published / Publiée :(c)
(51) 7 C07C 311/16, 311/29, C07D 317/46, A61K
31/36, A61P 31/18, A61K 31/352, C07D
493/04
(11) WO 00/76961 (13) A1
(21) PCT/US00/15781
(22) 8 Jun/juin 2000 (08.06.2000)
(25) en (26) en
(30) 60/139,070 11 Jun/juin 1999 US
(11.06.1999)
(30) 60/190,211 17 Mar/mar 2000 US
(17.03.2000)
(43) 21 Dec/déc 2000 (21.12.2000)
(54) INHIBITORS OF ASPARTYL PRO-
TEASE
INHIBITEURS D’ASPARTYL PRO-
TEASE
(71) VERTEX PHARMACEUTICALS IN-
CORPORATED [US/US]; 130 Waverly
Street, Cambridge, MA 02139-4242 (US).
(for all designated States except / pour tous
les États désignés sauf US)
(72, 75) HALE, Michael, Robin [US/US]; 42
Sunset Road, Bedford, MA 01730 (US).
TUNG, Roger [US/US]; 14 Thoreau Circle,
Beverly, MA 01915 (US). PRICE, Stephen
[GB/GB]; 25 Eskdale Road, Stoke Mandeville,
Aylesbury, Bucks HP22 5UJ (GB).
WILKES, Robin, David [GB/GB]; 7 Swarbourne
Close, Didcot, Oxon OX11 7UL
(GB). SCHAIRER, Wayne, Carl [US/US];
135 Milk Street, Westborough, MA 01581
(US). JARVIS, Ashley, Nicholas [GB/GB];
56 West Street, Osney, Oxford OX2 OBH
(GB). SPALTENSTEIN, Andrew [US/US];
4105 Brewster Drive, Raleigh, NC 27606
(US). FURFINE, Eric, Steven [US/US];
4133 Livingstone Place, Durham, NC 27707
(US). SAMANO, Vicente [MX/US]; 410 Englewood
Drive, Chapel Hill, NC 27514 (US).
KALDOR, Istvan [HU/US]; 7 Bonham
Court, Durham, NC 27703 (US). MILLER,
John, Franklin [US/US]; 310 Continental
Drive, Durham, NC 27712 (US). BRIEGER,
Michael, Stephen [US/US]; 2110 Paces
Forest Court #421, Raleigh, NC 27612 (US).
(74) HALEY, James, F., Jr.; Fish & Neave, 1251
Avenue of the Americas, New York, NY
10020 (US) et al. / etc.
(81) AE AG AL AM AT AU AZ BA BB BG BR
BY CA CH CN CR CU CZ DE DK DM DZ
EE ES FI GB GD GE GH GM HR HU ID IL
IN IS JP KE KG KP KR KZ LC LK LR LS
LT LU LV MA MD MG MK MN MW MX
MZ NO NZ PL PT RO RU SD SE SG SI SK
SL TJ TM TR TT TZ UA UG US UZ VN YU
ZA ZW.
(84) AP (GH GM KE LS MW MZ SD SL SZ TZ
UG ZW); EA (AM AZ BY KG KZ MD RU
TJ TM); EP (AT BE CH CY DE DK ES FI FR
GB GR IE IT LU MC NL PT SE); OA (BF BJ
CF CG CI CM GA GN GW ML MR NE SN
TD TG).
Published / Publiée :(c)
(51) 7 C07C 315/00, 53/00, 59/147
(11) WO 00/76962 (13) A1
(21) PCT/US00/16070
(22) 12 Jun/juin 2000 (12.06.2000)
(25) en (26) en
(30) 60/139,297 15 Jun/juin 1999 US
(15.06.1999)
(43) 21 Dec/déc 2000 (21.12.2000)
(54) THIOL DERIVATIVE, METALLO-
BETA-LACTAMASE INHIBITORS
DERIVES DE THIOL SERVANT D’IN-
HIBITEURS DES METALLO-BETA-
LACTAMASES
(71) MERCK & CO., INC. [US/US]; 126 East
Lincoln Avenue, Rahway, NJ 07065-0907
(US).
(for all designated States except / pour tous
les États désignés sauf US)
(72, 75) BALKOVEC, James, M. [US/US];
126 East Lincoln Avenue, Rahway, NJ
07065-0907 (US). GREENLEE, Mark, L.
[US/US]; 126 East Lincoln Avenue, Rahway,
NJ 07065-0907 (US). HAMMOND, Milton,
L. [US/US]; 126 East Lincoln Avenue, Rahway,
NJ 07065-0907 (US). HECK, James, V.
[US/US]; 126 East Lincoln Avenue, Rahway,
NJ 07065-0907 (US).
(74) MERCK & CO., INC.; 126 East Lincoln
Avenue, Rahway, NJ 07065-0907 (US).
(81) AE AG AL AM AT AU AZ BA BB BG BR
BY CA CH CN CR CU CZ DE DK DM DZ
EE ES FI GB GD GE GH GM HR HU ID IL
IN IS JP KE KG KR KZ LC LK LR LS LT
LU LV MA MD MG MK MN MW MX MZ
NO NZ PL PT RO RU SD SE SG SI SK SL
TJ TM TR TT TZ UA UG US UZ VN YU ZA
ZW.
(84) AP (GH GM KE LS MW MZ SD SL SZ TZ
UG ZW); EA (AM AZ BY KG KZ MD RU
TJ TM); EP (AT BE CH CY DE DK ES FI FR
GB GR IE IT LU MC NL PT SE); OA (BF BJ
CF CG CI CM GA GN GW ML MR NE SN
TD TG).
Published / Publiée :(c)
(51) 7 C07C 409/24, 407/00, A01N 37/36, C11D
3/39
(11) WO 00/76963
(21) PCT/EP00/05307
(13) A1
(22) 7 Jun/juin 2000 (07.06.2000)
(25) en (26) en
(30) 99304611.9 14 Jun/juin 1999
(14.06.1999)
EP
(43) 21 Dec/déc 2000 (21.12.2000)
(54) NEW PEROXY-CARBOXYLIC ACID
AND AQUEOUS COMPOSITIONS
THEREOF
NOUVEL ACIDE PEROXY-CAR-
BOXYLIQUE ET COMPOSITIONS
AQUEUSES DE CET ACIDE
(71) SOLVAY (SOCIÉTÉ ANONYME)
[BE/BE]; Rue du Prince Albert, 33, B-1050
Bruxelles (BE).
(for all designated States except / pour tous
les États désignés sauf US)