PCT/2000/51 - World Intellectual Property Organization

51/2000
19100 PCT Gazette - Section I - Gazette du PCT 21 Dec/déc 2000
(51) 7 C07D 405/12, 405/14, 409/14, 413/14,
417/14, A61K 31/55, A61P 31/18, 43/00
(11) WO 00/76993 (13) A1
(21) PCT/JP00/03879
(22) 15 Jun/juin 2000 (15.06.2000)
(25) ja (26) ja
(30) 11/170345 16 Jun/juin 1999 JP
(16.06.1999)
(43) 21 Dec/déc 2000 (21.12.2000)
(54) BENZAZEPINE DERIVATIVES,
PROCESS FOR THE PREPARATION
OF THE SAME AND USES THEREOF
DERIVES DE BENZAZEPINE, PRO-
CEDE DE PREPARATION DE CES
DERIVES ET UTILISATION
(71) TAKEDA CHEMICAL INDUSTRIES,
LTD. [JP/JP]; 1-1, Doshomachi 4-chome,
Chuo-ku, Osaka-shi, Osaka 541-0045 (JP).
(for all designated States except / pour tous
les États désignés sauf US)
(72, 75) SHIRAISHI, Mitsuru [JP/JP]; 33-26,
Tsukaguchicho 4-chome, Amagasaki-shi,
Hyogo 661-0002 (JP). BABA, Masanori
[JP/JP]; 54-19, Kotokujidai 3-chome,
Kagoshima-shi, Kagoshima 891-0103 (JP).
ARAMAKI, Yoshio [JP/JP]; 3-5-602,
Nishidai 1-chome, Itami-shi, Hyogo
664-0858 (JP). KANZAKI, Naoyuki [JP/JP];
2-15-203, Taishomachi, Ibaraki-shi, Osaka
567-0867 (JP). NISHIMURA, Osamu
[JP/JP]; 586-2, Ooaza-Higashihiratsuka,
Tsukuba-shi, Ibaraki 305-0812 (JP).
(74) TAKAHASHI, Shuichi et al. / etc.; Osaka
Plant of Takeda Chemical Industries,
Ltd., 17-85, Jusohonmachi 2-chome, Yodogawa-ku,
Osaka-shi, Osaka 532-0024 (JP).
(81) AE AG AL AM AU AZ BA BB BG BR BY
CA CN CR CU CZ DM DZ EE GD GE HR
HU ID IL IN IS JP KG KR KZ LC LK LR LT
LV MA MD MG MK MN MX MZ NO NZ
PL RO RU SG SI SK TJ TM TR TT UA US
UZ VN YU ZA.
(84) AP (GH GM KE LS MW MZ SD SL SZ TZ
UG ZW); EA (AM AZ BY KG KZ MD RU
TJ TM); EP (AT BE CH CY DE DK ES FI FR
GB GR IE IT LU MC NL PT SE); OA (BF BJ
CF CG CI CM GA GN GW ML MR NE SN
TD TG).
(51) 7 C07D 407/00
(11) WO 00/76994
(21) PCT/HU00/00054
(13) A2
(22) 6 Jun/juin 2000 (06.06.2000)
(25) en (26) en
(30) P 9901943 11 Jun/juin 1999
(11.06.1999)
HU
(43) 21 Dec/déc 2000 (21.12.2000)
(54) PROCESS FOR THE PREPARATION OF
FUMAGILLIN
PROCEDE DE PREPARATION DE LA
FUMAGILLINE
(71) SANOFI-SYNTHELABO [FR/FR]; 174,
avenue de France, F-75013 Paris (FR).
(for all designated States except / pour tous
les États désignés sauf US)
(72, 75) FARKAS, Gyula [HU/HU]; Tűzkő u.
8, H-1118 Budapest (HU). GYŐRBIRÓ,
Andrea [HU/HU]; Mátyáshegyi út 3,
H-1037 Budapest (HU). HERMECZ, István
[HU/HU]; Ráday u. 32, H-1092 Budapest
(HU). SIMON, Kálmán [HU/HU]; Ratkóc
u. 9, H-1118 Budapest (HU). SZABÓ, Anna
[HU/HU]; Berzeviczy G. u. 5/B, H-1042 Budapest
(HU). VASVÁRI, Árpádné [HU/HU];
Goldmark K. u. 33, H-1122 Budapest (HU).
(74) SANOFI-SYNTHELABO;György Mihályi
and Katalin Mármarosi, Tó u. 1-5, H-1045
Budapest (HU).
(81) AE AL AM AT AU AZ BA BB BG BR BY
CA CH CN CR CU CZ DE DK DM DZ EE
ES FI GB GD GE GH GM HR HU ID IL IN
IS JP KE KG KP KR KZ LC LK LR LS LT
LU LV MA MD MG MK MN MW MX MZ
NO NZ PL PT RO RU SD SE SG SI SK SL
TJ TM TR TT TZ UA UG US UZ VN YU ZA
ZW.
(84) AP (GH GM KE LS MW MZ SD SL SZ TZ
UG ZW); EA (AM AZ BY KG KZ MD RU
TJ TM); EP (AT BE CH CY DE DK ES FI FR
GB GR IE IT LU MC NL PT SE); OA (BF BJ
CF CG CI CM GA GN GW ML MR NE SN
TD TG).
(51) 7 C07D 417/06, A61K 31/5415, A61P 3/10
(11) WO 00/76995 (13) A1
(21) PCT/JP00/03741
(22) 8 Jun/juin 2000 (08.06.2000)
(25) ja (26) ja
(30) 11/167447 14 Jun/juin 1999 JP
(14.06.1999)
(43) 21 Dec/déc 2000 (21.12.2000)
(54) PROCESS FOR THE PREPARATION OF
(-)-1,4-BENZOTHIAZINE-2-ACETIC
ACID DERIVATIVES
PROCEDE DE PREPARATION DE
DERIVES DE L’ACIDE (-)-1,4-BENZO-
THIAZINE-2-ACETIQUE
(71) WELFIDE CORPORATION [JP/JP]; 6-9,
Hiranomachi 2-chome, Chuo-ku, Osaka-shi,
Osaka 541-0046 (JP). SENJU PHAR-
MACEUTICAL CO., LTD. [JP/JP]; 5-8,
Hiranomachi 2-chome, Chuo-ku, Osaka-shi,
Osaka 541-0046 (JP).
(for all designated States except / pour tous
les États désignés sauf US)
(72, 75) ONO, Yuji [JP/JP]; Welfide Corporation,
Research Laboratories, 955, Oaza-Koiwai,
Yoshitomimachi, Chikujo-gun, Fukuoka
871-8550 (JP). AKAHOSHI, Fumihiko
[JP/JP]; Welfide Corporation, Research
Laboratories, 25-1, Shodaiohtani
2-chome, Hirakata-shi, Osaka 573-1153
(JP). MORIGUCHI, Akihiko [JP/JP];
Welfide Corporation, Yoshitomi Plant, 955,
Oaza-Koiwai, Yoshitomimachi, Chikujo-gun,
Fukuoka 871-8550 (JP). UEMORI, Satoru
[JP/JP]; Welfide Corporation, Research
Laboratories, 955, Oaza-Koiwai, Yoshitomimachi,
Chikujo-gun, Fukuoka 871-8550
(JP). IKEBE, Tsuguo [JP/JP]; Welfide
Corporation, Research Laboratories, 955,
Oaza-Koiwai, Yoshitomimachi, Chikujo-gun,
Fukuoka 871-8550 (JP).
(74) TAKASHIMA, Hajime; Yuki Bldg., 3-9,
Hiranomachi 3-chome, Chuo-ku, Osaka-shi,
Osaka 541-0046 (JP).
(81) AE AG AL AM AT AU AZ BA BB BG BR
BY CA CH CN CR CU CZ DE DK DM DZ
EE ES FI GB GD GE GH GM HR HU ID IL
IN IS JP KE KG KR KZ LC LK LR LS LT
LU LV MA MD MG MK MN MW MX MZ
NO NZ PL PT RO RU SD SE SG SI SK SL
TJ TM TR TT TZ UA UG US UZ VN YU ZA
ZW.
(84) AP (GH GM KE LS MW MZ SD SL SZ TZ
UG ZW); EA (AM AZ BY KG KZ MD RU
TJ TM); EP (AT BE CH CY DE DK ES FI FR
GB GR IE IT LU MC NL PT SE); OA (BF BJ
CF CG CI CM GA GN GW ML MR NE SN
TD TG).
(51) 7 C07D 471/04 // (C07D 471/04, 221:00,
209:00)
(11) WO 00/76996 (13) A2
(21) PCT/EP00/05116
(22) 5 Jun/juin 2000 (05.06.2000)
(25) de (26) de
(30) 199 27 412.6 16 Jun/juin 1999 DE
(16.06.1999)
(43) 21 Dec/déc 2000 (21.12.2000)
(54) METHOD FOR THE ENANTIOMER
SEPARATION OF CIS-8-BEN-
ZYL-7,9-DIOXO-2,8-DIAZABICY-
CLO[4.3.0]NONANE
PROCEDE DE SEPARATION D’EN-
ANTIOMERES CONTENUS DANS
CIS-8-BENZYLE-7,9-DIOXO-2,8-DIA-
ZABICYCLO[4.3.0]NONANE
(71) BAYER AKTIENGESELLSCHAFT
[DE/DE]; D-51368 Leverkusen (DE).
(for all designated States except / pour tous
les États désignés sauf US)
(72, 75) FEY, Peter [DE/DE]; Am Eickhof 23,
D-42111 Wuppertal (DE).
(74) BAYER AKTIENGESELLSCHAFT;
D-51368 Leverkusen (DE).
(81) AE AG AL AM AT AU AZ BA BB BG BR
BY CA CH CN CR CU CZ DE DK DM DZ
EE ES FI GB GD GE GH GM HR HU ID IL
IN IS JP KE KG KP KR KZ LC LK LR LS
LT LU LV MA MD MG MK MN MW MX
MZ NO NZ PL PT RO RU SD SE SG SI SK
SL TJ TM TR TT TZ UA UG US UZ VN YU
ZA ZW.
(84) AP (GH GM KE LS MW MZ SD SL SZ TZ
UG ZW); EA (AM AZ BY KG KZ MD RU
TJ TM); EP (AT BE CH CY DE DK ES FI FR
GB GR IE IT LU MC NL PT SE); OA (BF BJ
CF CG CI CM GA GN GW ML MR NE SN
TD TG).
(51) 7 C07D 471/08, 471/20, A61K 31/435
(11) WO 00/76997
(21) PCT/SE00/01251
(13) A1
(22) 15 Jun/juin 2000 (15.06.2000)
(25) en (26) en
(30) 9902271-7 16 Jun/juin 1999
(16.06.1999)
SE
(43) 21 Dec/déc 2000 (21.12.2000)
(54) NEW BISPIDINE COMPOUNDS USE-
FUL IN THE TREATMENT OF CAR-
DIAC ARRHYTHMIAS
COMPOSES DE BISPIDINE POUVANT
ETRE UTILISES POUR LE TRAITE-
MENT DE L’ARYTHMIE CARDIAQUE
(71) ASTRAZENECA AB [SE/SE]; S-151 85
Södertälje (SE).
(for all designated States except / pour tous
les États désignés sauf US)