PCT/2000/51 - World Intellectual Property Organization

51/2000
21 Dec/déc 2000 PCT Gazette - Section I - Gazette du PCT 19013
GB GR IE IT LU MC NL PT SE); OA (BF BJ
CF CG CI CM GA GN GW ML MR NE SN
TD TG).
Published / Publiée :(a)
(51) 7 A61K 31/695, A61P 35/00, 9/10
(11) WO 00/76523 (13) A1
(21) PCT/US00/15912
(22) 9 Jun/juin 2000 (09.06.2000)
(25) en (26) en
(30) 60/138,968 11 Jun/juin 1999 US
(11.06.1999)
(43) 21 Dec/déc 2000 (21.12.2000)
(54) METHODS FOR MODULATING FXR
RECEPTOR ACTIVITY
PROCEDES DE MODULATION DE
L’ACTIVITE DU RECEPTEUR FXR
(71) ALLERGAN SALES, INC. [US/US]; 2525
Dupont Drive, Irvine, CA 92612 (US).
(for all designated States except / pour tous
les États désignés sauf US)
(72, 75) FORMAN, Barry, M. [US/US]; 1500
E. Duarte Road, Duarte, CA 91010-3000
(US). BEARD, Richard, L. [US/US]; 2341
Azure Avenue, Newport Beach, CA 92660
(US). CHANDRARATNA, Roshantha, A.
[US/US]; 25241 Buckskin, Laguna Hills, CA
92653 (US).
(74) FISHER, Carlos, A. et al. / etc.; Allergan
Sales, Inc., 2525 Dupont Drive, Irvine, CA
92612 (US).
(81) AE AL AM AT AU AZ BA BB BG BR BY
CA CH CN CR CU CZ DE DK DM EE ES FI
GB GD GE GH GM HR HU ID IL IN IS JP
KE KG KP KR KZ LC LK LR LS LT LU LV
MA MD MG MK MN MW MX NO NZ PL
PT RO RU SD SE SG SI SK SL TJ TM TR
TT TZ UA UG US UZ VN YU ZA ZW.
(84) AP (GH GM KE LS MW MZ SD SL SZ TZ
UG ZW); EA (AM AZ BY KG KZ MD RU
TJ TM); EP (AT BE CH CY DE DK ES FI FR
GB GR IE IT LU MC NL PT SE); OA (BF BJ
CF CG CI CM GA GN GW ML MR NE SN
TD TG).
(51) 7 A61K 31/70
(11) WO 00/76524
(21) PCT/US00/16037
(13) A1
(22) 9 Jun/juin 2000 (09.06.2000)
(25) en (26) en
(30) 09/330,905 11 Jun/juin 1999
(11.06.1999)
US
(43) 21 Dec/déc 2000 (21.12.2000)
(54) COMBINATION CANCER THERAPY
COMPRISING ADENOSINE AND
DEAMINASE ENZYME INHIBITOR
POLYTHERAPIE ANTICANCEREUSE
UTILISANT UN INHIBITEUR D’EN-
ZYME ADENOSINE DESAMINASE
(71) EVANSTON NORTHWESTERN
HEALTHCARE RESEARCH INSTI-
TUTE [US/US]; 1033 University Place,
Suite 100, Evanston, IL 60201-3156 (US).
(72) LIND, Stuart, E.; 860 Hibbard Road, Winnetka,
IL 60093 (US). BARRY, Catherine,
P.; 526 Hermitage Drive, Deerfield, IL 60015
(US).
(74) HOPKINS, Mark, H.; Marshall, O’Toole,
Gerstein, Murray & Borun, 6300 Sears Tower,
233 South Wacker Drive, Chicago, IL 60606-
6402 (US).
(81) AE AG AL AM AT AU AZ BA BB BG BR
BY CA CH CN CR CU CZ DE DK DM DZ
EE ES FI GB GD GE GH GM HR HU ID IL
IN IS JP KE KG KP KR KZ LC LK LR LS
LT LU LV MA MD MG MK MN MW MX
MZ NO NZ PL PT RO RU SD SE SG SI SK
SL TJ TM TR TT TZ UA UG UZ VN YU ZA
ZW.
(84) AP (GH GM KE LS MW MZ SD SL SZ TZ
UG ZW); EA (AM AZ BY KG KZ MD RU
TJ TM); EP (AT BE CH CY DE DK ES FI FR
GB GR IE IT LU MC NL PT SE); OA (BF BJ
CF CG CI CM GA GN GW ML MR NE SN
TD TG).
Published / Publiée :(a)
(51) 7 A61K 31/704, 47/26, 47/14, 9/10, A61P
35/00, C07H 15/252
(11) WO 00/76525 (13) A1
(21) PCT/JP00/03849
(22) 14 Jun/juin 2000 (14.06.2000)
(25) ja (26) ja
(30) 11/166928 14 Jun/juin 1999 JP
(14.06.1999)
(43) 21 Dec/déc 2000 (21.12.2000)
(54) ANTICANCER EMULSIONS CON-
TAINING ANTHRACYCLINE COM-
POUNDS
EMULSIONS ANTICANCEREUSES
CONTENANT DES COMPOSES D’AN-
THRACYCLINE
(71) MEIJI MILK PRODUCTS CO., LTD.
[JP/JP]; 3-6, Kyobashi 2-chome, Chuo-ku,
Tokyo 104-0031 (JP). JAPAN SCIENCE
AND TECHNOLOGY CORPORA-
TION [JP/JP]; 1-8, Honcho 4-chome,
Kawaguchi-shi, Saitama 332-0012 (JP).
(for all designated States except / pour tous
les États désignés sauf US)
(72, 75) OYAMA, Kaho [JP/JP]; Meiji Milk
Products Co., Ltd., Pharmaceuticals Development
Department, 540, Naruda, Odawara-shi,
Kanagawa 250-0862 (JP). OTSUBO, Kazumitsu
[JP/JP]; Meiji Milk Products Co.,
Ltd., Pharmaceuticals Development Department,
540, Naruda, Odawara-shi, Kanagawa
250-0862 (JP). OTSUKA, Suguru [JP/JP];
Meiji Milk Products Co., Ltd., Pharmaceuticals
Development Department, 540, Naruda,
Odawara-shi, Kanagawa 250-0862 (JP).
(74) ARUGA, Mitsuyuki et al. / etc.; Kyodo
Building, 3-6, Nihonbashiningyocho
1-chome, Chuo-ku, Tokyo 103-0013 (JP).
(81) AU BG BR CA CN ID IN JP KP KR LK MX
NZ PL SG US VN ZA.
(84) AP (GH GM KE LS MW MZ SD SL SZ TZ
UG ZW); EA (AM AZ BY KG KZ MD RU
TJ TM); EP (AT BE CH CY DE DK ES FI FR
GB GR IE IT LU MC NL PT SE); OA (BF BJ
CF CG CI CM GA GN GW ML MR NE SN
TD TG).
(51) 7 A61K 31/704, 31/44, 49/00
(11) WO 00/76526 (13) A1
(21) PCT/US00/15414
(22) 1 Jun/juin 2000 (01.06.2000)
(25) en (26) en
(30) 09/329,848 11 Jun/juin 1999 US
(11.06.1999)
(43) 21 Dec/déc 2000 (21.12.2000)
(54) METHOD FOR THE PREVENTION
AND TREATMENT OF CHRONIC VE-
NOUS INSUFFICIENCY
METHODE DE PREVENTION ET DE
TRAITEMENT DE L’INSUFFISANCE
VEINEUSE CHRONIQUE
(71) UNIVERA PHARMACEUTICALS, INC.
[US/US]; Suite 160, 100 Technology Drive,
Broomfield, CO 80021 (US).
(72) JIA, Qi; 8186 Gray Court, Arvada, CO
80003 (US). QIU, Zhihua; 5840 West
112th Place, Westminster, CO 80021 (US).
MAHIOU, Belaid; 13493 Quivas Street,
Westminster, CO 80234 (US). FARROW,
Thomas, M.; 660 El Paso Blvd., Denver, CO
80221 (US). NISSANKA, Ajith; 5875 N.
Orchard Creek Circle, Boulder, CO 80301
(US).
(74) SWANSON, Barry, J. et al. / etc.; Swanson
& Bratschun, L.L.C., Suite 330, 1745 Shea
Center Drive, Highlands Ranch, CO 80129
(US).
(81) JP KR.
(84) EP (AT BE CH CY DE DK ES FI FR GB GR
IE IT LU MC NL PT SE).
(51) 7 A61K 35/12
(11) WO 00/76527 (13) A2
(21) PCT/EP00/05202
(22) 6 Jun/juin 2000 (06.06.2000)
(25) en (26) en
(30) 99401385.2 9 Jun/juin 1999 EP
(09.06.1999)
(43) 21 Dec/déc 2000 (21.12.2000)
(54) NEW MOLECULAR COMPLEXES
PRESENTING HIGH AFFINITY BIND-
ING WITH RESPECT TO MONOCYTE
DERIVED CELLS AND THEIR USES
IN THERAPY
NOUVEAUX COMPLEXES MOLE-
CULAIRES A FORTE AFFINITE DE
LIAISON AVEC DES CELLULES MO-
NOCYTES ET LEURS APPLICATIONS
THERAPEUTIQUES
(71) I.D.M. IMMUNO-DESIGNED
MOLECULES [FR/FR]; 172, rue de
Charonne, F-75011 Paris (FR).
(for all designated States except / pour tous
les États désignés sauf US)
(72, 75) BARTHOLEYNS, Jacques [FR/FR];
Manoir de la Vignole, 1, impasse Marguerite
d’Anjou, F-49730 Turquant (FR).
ROMET-LEMONNE, Jean-Loup [FR/FR];
8, rue de Hesse, F-75003 Paris (FR).
(74) GROSSET-FOURNIER, Chantal et al. /
etc.; Grosset-Fournier & Demachy s.a.r.l., 20,
rue de Maubeuge, F-75009 Paris (FR).
(81) AG AL AM AT AU AZ BA BB BG BR BY
CA CH CN CR CU CZ DE DK DM DZ EE
ES FI GB GD GE GH GM HR HU ID IL IN
IS JP KE KG KP KR KZ LC LK LR LS LT
LU LV MA MD MG MK MN MW MX MZ
NO NZ PL PT RO RU SD SE SG SI SK SL TJ
TM TR TT TZ UA UG US UZ VN YU ZW.