PCT/1998/43 - World Intellectual Property Organization

43/1998
15028 PCT Gazette - Section I - Gazette du PCT 29 Oct/oct 1998
(25) en (26) en
(31) 60/044,727 (32) 21 Apr/avr 1997 (33) US
(21.04.1997)
(43) 29 Oct/oct 1998 (29.10.1998)
(51) 6 C12P 21/00
(54) • POLY–( –L–ASPARTIC ACID), POLY–( –L–
GLUTAMIC ACID) AND COPOLYMERS OF
L–ASP AND L–GLU, METHOD FOR THEIR
PRODUCTION AND THEIR USE
• ACIDE POLY– –L–ASPARTIQUE, ACIDE–
POLY– –L–GLUTAMIQUE ET COPOLY-
MERES DE L–ASP ET L–GLU, LEUR
PROCEDE DE PREPARATION ET LEUR
UTILISATION
(71) DEGUSSA AKTIENGESELLSCHAFT
[DE/DE]; Weissfrauenstrasse 9, D–60311 Frankfurt
(DE). UNIVERSITY OF MASSACHUSETTS
[US/US]; One Beacon Street, 26th floor, Boston,
MA 02108 (US).
(for all designated States except / pour tous les États
désignés sauf US)
(72, 75) TIRRELL, David, A. [US/US]; 101 N.
Plain Road, Sunderland, MA 01375 (US). DEL
GROSSO, Michael [DE/DE]; Waldstrasse 23,
D–63579 Freigericht (DE). SIEGMEIER, Rainer
[DE/DE]; Anspacher Strasse 35, D–61350
Bad Homburg (DE). BOMMARIUS, Andreas
[DE/DE]; Waidmannstrasse 7–9, D–60596 Frankfurt
(DE).
(81) US; EP (AT BE CH CY DE DK ES FI FR GB GR
IE IT LU MC NL PT SE).
(11) WO 98/48033 (13) A1
(21) PCT/JP97/01403
(22) 23 Apr/avr 1997 (23.04.1997)
(25) ja (26) ja
(43) 29 Oct/oct 1998 (29.10.1998)
(51) 6 C12P 21/00, C12N 1/20 // (C12N 1/20, C12R
1:465)
(54) • STRAIN PRODUCING REMARKABLE
AMOUNT OF –POLY–L–LYSINE AND PRO-
CESS FOR PRODUCING –POLY–L–LYSINE
BY USING THE SAME
• SOUCHE PRODUISANT UNE QUANTITE
IMPORTANTE DE –POLY–L–LYSINE ET
PROCEDE POUR PRODUIRE DE LA –
POLY–L–LYSINE AU MOYEN DE CETTE
SOUCHE
(71) CHISSO CORPORATION [JP/JP]; 6–32,
Nakonoshima 3–chome, Kita–ku, Osaka–shi,
Osaka 530 (JP).
(72) IWATA, Toshiharu; 10–3, Ottomo–cho, Kanazawa–ku,
Yokohama–shi, Kanagawa 236 (JP).
IWASAWA, Yumiko; 133, Kamiyamaguchi,
Hayama–cho, Miura–gun, Kanagawa 240–01
(JP). SHIRAISHI, Shinji; 10–3, Ottomo–cho,
Kanazawa–ku, Yokohama–shi, Kanagawa 236
(JP). HIRAKI, Jun; 10–1–104, Ottomo–cho,
Kanazawa–ku, Yokohama–shi, Kanagawa 236
(JP).
(74) HAGINO, Taira et al. / etc.; Eikoh Patent Office,
ARK Mori Building, 28th floor, 12–32, Akasaka
1–chome, Minato–ku, Tokyo 107 (JP).
(81) CN KR SG VN.
(11) WO 98/48034 (13) A1
(21) PCT/EP98/02460
(22) 22 Apr/avr 1998 (22.04.1998)
(25) en (26) en
(31) 97201196.9 (32) 22 Apr/avr 1997
(22.04.1997)
(33) EP
(34) NL et al. / etc.
(43) 29 Oct/oct 1998 (29.10.1998)
(51) 6 C12P 35/00, 37/04, C12N 15/52, 15/54
(54) • PROCESS FOR THE FERMENTATIVE PRO-
DUCTION OF DEACYLATED CEPHALO-
SPORINS
• PROCEDE DE PRODUCTION FERMENTA-
TIVE DE CEPHALOSPORINES DESACY-
LEES
(71) GIST–BROCADES B.V. [NL/NL]; Wateringseweg
1, P.O. Box 1, NL–2600 MA Delft (NL).
(for all designated States except / pour tous les États
désignés sauf US)
(72, 75) NIEBOER, Maarten [NL/NL]; Gerberasingel
112, NL–2651 XZ Berkel en Rodenrijs (NL).
DE VROOM, Erik [NL/NL]; De Meij van
Streefkerkstraat 65, NL–2313 JM Leiden (NL).
LUGTENBURG, Johannis [NL/NL]; Laan van
Oud Poelgeest 22, NL–2341 NK Oegstgeest
(NL). SCHIPPER, Dirk [NL/NL]; Oostsingel
205, NL–2612 HL Delft (NL). VOLLEBREGT,
Andrianus, Wilhelmus, Hermanus [US/US];
Bereklauw 13, NL–2671 WZ NAALDWIJK (US).
BOVENBERG, Roelof, Ary, Lans [NL/NL];
’s–Gravenweg 121, NL–3062 ZD Rotterdam (NL).
(74) VISSER–LUIRINK, Gesina et al. / etc.;
Gist–Brocades B.V., Patents and Trademarks
Dept., Wateringseweg 1, P.O. Box 1, NL–2600
MA Delft (NL).
(81) AL AM AT AU AZ BA BB BG BR BY CA CH
CN CU CZ DE DK EE ES FI GB GE GH GM GW
HU ID IL IS JP KE KG KP KR KZ LC LK LR
LS LT LU LV MD MG MK MN MW MX NO NZ
PL PT RO RU SD SE SG SI SK SL TJ TM TR
TT UA UG US UZ VN YU ZW; AP (GH GM KE
LS MW SD SZ UG ZW); EA (AM AZ BY KG
KZ MD RU TJ TM); EP (AT BE CH CY DE DK
ES FI FR GB GR IE IT LU MC NL PT SE); OA
(BF BJ CF CG CI CM GA GN ML MR NE SN
TD TG).
Published / Publiée : (c)
(11) WO 98/48035 (13) A1
(21) PCT/EP98/02461
(22) 22 Apr/avr 1998 (22.04.1998)
(25) en (26) en
(31) 97201197.7 (32) 22 Apr/avr 1997 (33) EP
(22.04.1997)
(34) NL et al. / etc.
(43) 29 Oct/oct 1998 (29.10.1998)
(51) 6 C12P 35/00, 37/04, C12N 15/52, 15/54
(54) • PROCESS FOR THE FERMENTATIVE PRO-
DUCTION OF DEACYLATED CEPHALO-
SPORINS
• PROCEDE DE PRODUCTION FERMENTA-
TIVE DE CEPHALOSPORINES DESACY-
LEES
(71) GIST–BROCADES B.V. [NL/NL]; Wateringseweg
1, P.O. Box 1, NL–2600 MA Delft (NL).
(for all designated States except / pour tous les États
désignés sauf US)
(72, 75) NIEBOER, Maarten [NL/NL]; Gerberasingel
112, NL–2651 XZ Berkel en Rodenrijs (NL).
DE VROOM, Erik [NL/NL]; De Meij van
streefkerkstraat 65, NL–2313 JM Leiden (NL).
LUGTENBURG, Johannis [NL/NL]; Laan van
Oud Poelgeest 22, NL–2341 NK Oegstgeest
(NL). SCHIPPER, Dirk [NL/NL]; Oostsingel
205, NL–2612 HL Delft (NL). VOLLEBREGT,
Adrianus, Wilhelmus, Hermanus [NL/NL];
Bereklauw 13, NL–2671 WZ Naaldwijk (NL).
BOVENBERG, Roelof, Ary, Lans [NL/NL];
’s–Gravenweg 121, NL–3062 ZD Rotterdam (NL).
(74) VISSER–LUIRINK, Gesina et al. / etc.;
Gist–Brocades B.V., Patents and Trademarks
Dept., Wateringseweg 1, P.O. Box 1, NL–2600
MA Delft (NL).
(81) AL AM AT AU AZ BA BB BG BR BY CA CH
CN CU CZ DE DK EE ES FI GB GE GH GM GW
HU ID IL IS JP KE KG KP KR KZ LC LK LR
LS LT LU LV MD MG MK MN MW MX NO NZ
PL PT RO RU SD SE SG SI SK SL TJ TM TR
TT UA UG US UZ VN YU ZW; AP (GH GM KE
LS MW SD SZ UG ZW); EA (AM AZ BY KG
KZ MD RU TJ TM); EP (AT BE CH CY DE DK
ES FI FR GB GR IE IT LU MC NL PT SE); OA
(BF BJ CF CG CI CM GA GN ML MR NE SN
TD TG).
Published / Publiée : (c)
(11) WO 98/48036 (13) A1
(21) PCT/EP98/02459
(22) 22 Apr/avr 1998 (22.04.1998)
(25) en (26) en
(31) 97201201.7 (32) 22 Apr/avr 1997 (33) EP
(22.04.1997)
(34) AT et al. / etc.
(43) 29 Oct/oct 1998 (29.10.1998)
(51) 6 C12P 35/02
(54) • IMPROVED PROCESS FOR THE FERMEN-
TATIVE PRODUCTION OF CEPHALOSPO-
RIN
• PROCEDE AMELIORE DE PRODUCTION
FERMENTATIVE DE CEPHALOSPORINE
(71) GIST–BROCADES B.V. [NL/NL]; Wateringseweg
1, P.O. Box 1, NL–2600 MA Delft (NL).
(for all designated States except / pour tous les États
désignés sauf US)
(72, 75) KRIJGSMAN, John [NL/NL]; Herculesring
17, NL–3328 HJ Dordrecht (NL). SMEETS, Jan,
Willem, Hubert [NL/NL]; Henri Dunantlaan 3,
NL–3135 WB Vlaardingen (NL). DE BRAAL,
Henriëtte, Elisabeth, Anna [NL/NL]; Van der
Haertstraat 41, NL–2613 ZA Delft (NL). DE
VROOM, Erik [NL/NL]; De Meij van Streefkerkstraat
65, NL–2313 JM Leiden (NL). FASEL, Herman,
Pieter [NL/NL]; Fien de La Marstraat 31,
NL–2331 HM Leiden (NL).
(74) VISSER–LUIRINK, Gesina et al. / etc.;
Gist–Brocades B.V., Patents and Trademarks
Dept., Wateringseweg 1, P.O. Box 1, NL–2600
MA Delft (NL).
(81) AL AM AT AU AZ BA BB BG BR BY CA CH
CN CU CZ DE DK EE ES FI GB GE GH GM GW
HU ID IL IS JP KE KG KP KR KZ LC LK LR
LS LT LU LV MD MG MK MN MW MX NO NZ
PL PT RO RU SD SE SG SI SK SL TJ TM TR
TT UA UG US UZ VN YU ZW; AP (GH GM KE
LS MW SD SZ UG ZW); EA (AM AZ BY KG
KZ MD RU TJ TM); EP (AT BE CH CY DE DK
ES FI FR GB GR IE IT LU MC NL PT SE); OA
(BF BJ CF CG CI CM GA GN ML MR NE SN
TD TG).
Published / Publiée : (c)
(11) WO 98/48037
(21) PCT/EP98/02457
(13) A1
(22) 22 Apr/avr 1998 (22.04.1998)
(25) en (26) en
(31) 97201199.3
(34) AT et al. / etc.
(32) 22 Apr/avr 1997
(22.04.1997)
(33) EP
(43) 29 Oct/oct 1998 (29.10.1998)
(51) 6 C12P 35/04, 37/04, 35/02, 37/06, C07D 501/20,
499/44
(54) • A METHOD FOR CONTROLLING THE SO-
LUBILITY OF A –LACTAM NUCLEUS
•
PROCEDE DE REGULATION DE LA SOLU-
BILITE D’UNE BETALACTAMINE