PCT/1998/43 - World Intellectual Property Organization

43/1998
29 Oct/oct 1998 PCT Gazette - Section I - Gazette du PCT 14943
(54) • IBUPROFEN THIOESTERS AS INHIBITORS
OF Nf– B–DEPENDENT PAIN AND IN-
FLAMMATION MEDIATOR FORMATION
• THIOESTERS D’IBUPROFENE UTILISES
COMME INHIBITEURS DE LA FORMATION
DE MEDIATEURS D’INFLAMMATION ET
DE DOULEUR Nf– –DEPENDANTE
(71) PAZ ARZNEIMITTEL–
ENTWICKLUNGSGESELLSCHAFT MBH
[DE/DE]; In der Schildwacht 13, D–65933
Frankfurt am Main (DE).
(for all designated States except / pour tous les États
désignés sauf US)
(72, 75) BANG, Holger [DE/DE]; Hofmannstrasse 118,
D–91052 Erlangen (DE). BRUNE, Kay [DE/DE];
Weiherackerweg 17, D–91080 Rathsberg (DE).
GEISSLINGER, Gerd [DE/DE]; Geiwitzenweg
29, D–91085 Weisendorf (DE). PAHL, Andreas
[DE/DE]; Ritzer Strasse 13, D–91054 Erlangen
(DE). SCHEUREN, Nicole [DE/DE]; Drausnickstrasse
30, D–91052 Erlangen (DE). NEUPERT,
Werner [DE/DE]; Reuthlehenstrasse 38, D–91056
Erlangen (DE).
(74) WEICKMANN, H. et al. / etc.; Kopernikusstrasse
9, D–81679 München (DE).
(81) CA JP RU US; EP (AT BE CH CY DE DK ES FI
FR GB GR IE IT LU MC NL PT SE).
Published / Publiée : (c)
(11) WO 98/47503 (13) A1
(21) PCT/JP98/01821
(22) 21 Apr/avr 1998 (21.04.1998)
(25) ja (26) ja
(31) 9/102923 (32) 21 Apr/avr 1997 (33) JP
(21.04.1997)
(43) 29 Oct/oct 1998 (29.10.1998)
(51) 6 A61K 31/19, 9/107, A61L 2/04
(54) • IBUPROFEN SUSPENSION PREPARATIONS
• PREPARATIONS EN SUSPENSION A BASE
D’IBUPROFENE
(71) TAISHO PHARMACEUTICAL CO., LTD.
[JP/JP]; 24–1, Takata 3–chome, Toshima–ku,
Tokyo 170–8633 (JP).
(for all designated States except / pour tous les États
désignés sauf US)
(72, 75) OBATA, Kiyotaka [JP/JP]; Taisho Pharmaceutical
Co., Ltd., 24–1, Takata 3–chome,
Toshima–ku, Tokyo 170–8633 (JP). YAMAGI-
SHI, Michio [JP/JP]; Taisho Pharmaceutical Co.,
Ltd., 24–1, Takata 3–chome, Toshima–ku, Tokyo
170–8633 (JP). NAITO, Mayumi [JP/JP]; Taisho
Pharmaceutical Co., Ltd., 24–1, Takata 3–chome,
Toshima–ku, Tokyo 170–8633 (JP).
(74) HIRAKI, Yusuke et al. / etc.; Toranomon No.
5 Mori Building, 3rd floor, 17–1 Toranomon
1–chome, Minato–ku, Tokyo 105–0001 (JP).
(81) AU CA CN JP KR US; EP (AT BE CH CY DE
DK ES FI FR GB GR IE IT LU MC NL PT SE).
(11) WO 98/47504
(21) PCT/JP98/01654
(13) A1
(22) 10 Apr/avr 1998 (10.04.1998)
(25) ja (26) ja
(31) 9/135675 (32) 18 Apr/avr 1997
(18.04.1997)
(33) JP
(43) 29 Oct/oct 1998 (29.10.1998)
(51) 6 A61K 31/195
(54) • PREVENTIVES OR REMEDIES FOR DI-
SEASES AFFECTING EXCESSIVE PRO-
LIFERATION OF RETINAL PIGMENT
EPITHELIAL CELLS
•
REMEDES POUR LA PROPHYLAXIE OU LE
TRAITEMENT DE MALADIES SE TRADUI-
SANT PAR UNE PROLIFERATION EXCES-
SIVE DES CELLULES EPITHELIALES PIG-
MENTAIRES DE LA RETINE
(71) KISSEI PHARMACEUTICAL CO., LTD.
[JP/JP]; 19–48, Yoshino, Matsumoto–shi, Nagano
399–8710 (JP).
(for all designated States except / pour tous les États
désignés sauf US)
(72, 75) TAKEHANA, Yasuo [JP/JP]; Maruyama–Manshon
202, 1164–9, Oaza Toyoshina,
Toyoshina–machi, Minami–azumi–gun, Nagano
399–8205 (JP). KITAZAWA, Makio [JP/JP];
2–2–6, Kotobukikita, Matsumoto–shi, Nagano
399–0011 (JP).
(81) AL AM AT AU AZ BA BB BG BR BY CA CH
CN CU CZ DE DK EE ES FI GB GE GM GW
HU ID IL IS JP KE KG KR KZ LC LK LR LS LT
LU LV MD MG MK MN MW MX NO NZ PL PT
RO RU SD SE SG SI SK TJ TM TR TT UA UG
US UZ VN; AP (GH GM KE LS MW SD SZ UG
ZW); EA (AM AZ BY KG KZ MD RU TJ TM);
EP (AT BE CH CY DE DK ES FI FR GB GR IE
IT LU MC NL PT SE); OA (BF BJ CF CG CI CM
GA GN ML MR NE SN TD TG).
(11) WO 98/47505 (13) A1
(21) PCT/JP98/01855
(22) 22 Apr/avr 1998 (22.04.1998)
(25) ja (26) ja
(31) 9/120310 (32) 23 Apr/avr 1997
(23.04.1997)
(33) JP
(43) 29 Oct/oct 1998 (29.10.1998)
(51) 6 A61K 31/35 // C07D 311/80
(54) • NEUROPEPTIDE Y RECEPTOR ANTAGO-
NIST
• ANTAGONISTE DE RECEPTEUR DE
NEUROPEPTIDE Y
(71) BANYU PHARMACEUTICAL CO., LTD.
[JP/JP]; 2–3, Nihombashi Honcho 2–chome,
Chuo–ku, Tokyo 103–8416 (JP).
(for all designated States except / pour tous les États
désignés sauf US)
(72, 75) FUKAMI, Takehiro [JP/JP]; Banyu Pharmaceutical
Co., Ltd. Tsukuba Research Institute, 3,
Okubo, Tsukuba–shi, Ibaraki 300–2611 (JP). FU-
KURODA, Takahiro [JP/JP]; Banyu Pharmaceutical
Co., Ltd. Tsukuba Research Institute, 3, Okubo,
Tsukuba–shi, Ibaraki 300–2611 (JP). KANATANI,
Akio [JP/JP]; Banyu Pharmaceutical Co., Ltd. Tsukuba
Research Institute, 3, Okubo, Tsukuba–shi,
Ibaraki 300–2611 (JP). IHARA, Masaki [JP/JP];
Banyu Pharmaceutical Co., Ltd. Tsukuba Research
Institute, 3, Okubo, Tsukuba–shi, Ibaraki 300–2611
(JP). OKABE, Takayoshi [JP/JP]; Banyu Pharmaceutical
Co., Ltd. Tsukuba Research Institute, 3,
Okubo, Tsukuba–shi, Ibaraki 300–2611 (JP).
(74) BANYU PHARMACEUTICAL CO., LTD.; 2–3,
Nihombashi Honcho 2–chome, Chuo–ku, Tokyo
103–8416 (JP).
(81) AL AM AT AU AZ BA BB BG BR BY CA CH
CN CU CZ DE DK EE ES FI GB GE GH GM
GW HU ID IL IS JP KE KG KR KZ LC LK LR
LS LT LU LV MD MG MK MN MW MX NO NZ
PL PT RO RU SD SE SG SI SK SL TJ TM TR
TT UA UG US UZ VN YU ZW; AP (GH GM KE
LS MW SD SZ UG ZW); EA (AM AZ BY KG
KZ MD RU TJ TM); EP (AT BE CH CY DE DK
ES FI FR GB GR IE IT LU MC NL PT SE); OA
(BF BJ CF CG CI CM GA GN ML MR NE SN
TD TG).
Published / Publiée : (c)
(11) WO 98/47506 (13) A1
(21) PCT/FR98/00755
(22) 15 Apr/avr 1998 (15.04.1998)
(25) fr (26) fr
(31) 97/04803 (32) 18 Apr/avr 1997
(18.04.1997)
(33) FR
(43) 29 Oct/oct 1998 (29.10.1998)
(51) 6 A61K 31/40, 9/00
(54) • GASTRIC–RETAINED PHARMACEUTICAL
COMPOSITION
• COMPOSITION PHARMACEUTIQUE A RE-
SIDENCE GASTRIQUE
(71) SYNTHELABO [FR/FR]; 22, avenue Galilée,
F–92350 Le Plessis Robinson (FR).
(for all designated States except / pour tous les États
désignés sauf US)
(72, 75) BESSE, Jérôme [FR/FR]; Chemin des Vins,
1276 Barbat, F–33480 Listrac Médoc (FR).
(74) THOURET–LEMAITRE, Elisabeth; Synthelabo,
22, avenue Galilée, F–92350 Le Plessis Robinson
(FR).
(81) AL AM AT AU AZ BA BB BG BR BY CA CH
CN CU CZ DE DK EE ES FI GB GE GH GM GW
HU ID IL IS JP KE KG KP KR KZ LC LK LR
LS LT LU LV MD MG MK MN MW MX NO NZ
PL PT RO RU SD SE SG SI SK SL TJ TM TR
TT UA UG US UZ VN YU ZW; AP (GH GM KE
LS MW SD SZ UG ZW); EA (AM AZ BY KG
KZ MD RU TJ TM); EP (AT BE CH CY DE DK
ES FI FR GB GR IE IT LU MC NL PT SE); OA
(BF BJ CF CG CI CM GA GN ML MR NE SN
TD TG).
(11) WO 98/47507 (13) A1
(21) PCT/JP97/01421
(22) 24 Apr/avr 1997 (24.04.1997)
(25) en (26) en
(43) 29 Oct/oct 1998 (29.10.1998)
(51) 6 A61K 31/40, 31/435
(54) • METHOD FOR THE TREATMENT OF
STROKE USING N–HETEROCYCLIC
GLYOXYLAMIDE COMPOUNDS
• TRAITEMENT DES ACCIDENTS VAS-
CULAIRES CEREBRAUX A L’AIDE DE
COMPOSES DE GLYOXYLAMIDE N–
NETEROCYCLIQUES
(71) SHIONOGI & CO., LTD. [JP/JP]; 1–8, Doshomachi
3–chome, Chuo–ku, Osaka–shi, Osaka 541
(JP).
(72) GENBA, Takefumi; 4–24–15, Minamihanayashiki,
Kawanishi–shi, Hyogo 666 (JP). HORI, Yozo;
7–4–29, Nagaomotomachi, Hirakata–shi, Osaka
573–01 (JP).
(74) YAMAUCHI, Hideaki; 12–4, Sagisu 5–chome,
Fukushima–ku, Osaka–shi, Osaka 553–0002 (JP).
(81) JP.
(11) WO 98/47508 (13) A1
(21) PCT/JP98/01880
(22) 23 Apr/avr 1998 (23.04.1998)
(25) en (26) en
(31) PCT/JP97/01421 (32) 24 Apr/avr 1997 (33) WO
(24.04.1997)
(34) JP
(43) 29 Oct/oct 1998 (29.10.1998)
(51) 6 A61K 31/40, 31/435