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Narcissus and Daffodil

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HCO<br />

3<br />

O<br />

O<br />

6<br />

O<br />

H<br />

N<br />

R<br />

OH<br />

Lycoramine 3,<br />

R=CH3<br />

DemethyI-Iycoramine 4,<br />

R=H<br />

O<br />

O<br />

Haemanthamine 7<br />

R1<br />

3<br />

O<br />

N<br />

1<br />

2<br />

OR2<br />

H<br />

NH<br />

OH<br />

Narciclasine 9, R 1=OH<br />

R=H 2<br />

Lycoricidine , R =R =H<br />

10 1 2<br />

Agronomic factors <strong>and</strong> galanthamine production 275<br />

OCH3<br />

OR2<br />

OR2<br />

Structural formulae of the Amaryllidaceae alkaloids<br />

At the National Center for Natural Products Research, the potential of <strong>Narcissus</strong><br />

cultivars as sources of galanthamine <strong>and</strong> related alkaloids has been recognised, <strong>and</strong><br />

research has been initiated on the agronomic factors that affect galanthamine content<br />

in them. <strong>Narcissus</strong> has two important advantages over Leucojum aestivum: firstly,<br />

O<br />

O<br />

O<br />

O<br />

O<br />

O<br />

Caranine 5,<br />

R=H<br />

Lycorine 6,<br />

R=OH<br />

H<br />

N<br />

HO<br />

H<br />

O<br />

H<br />

H<br />

O<br />

R<br />

Hippeastrine 8<br />

OCH3<br />

OH<br />

O<br />

Pretazettine 11<br />

H<br />

N<br />

H<br />

H<br />

N<br />

OH

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