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Narcissus and Daffodil

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416 J.R. Murray<br />

given at a time between 4 a.m. <strong>and</strong> 3 p.m. of the time zone to be visited. To ‘reset<br />

the clock’, galanthamine should be administered at least 8 hours prior to the<br />

desired time of sleep. The authors believe such therapy could also be relevant to<br />

shift workers (Davis, 1996).<br />

CONCLUSIONS<br />

The powers of the genus <strong>Narcissus</strong> can be seen to be many <strong>and</strong> varied. Each plant<br />

should have its specific medical use, <strong>and</strong> clearly cognitive disorders <strong>and</strong> Alzheimer’s<br />

Disease in particular must be the c<strong>and</strong>idates for the daffodil. However,<br />

various forms of sexual dysfunction that can lead to severe strain on otherwise<br />

meaningful partnerships, <strong>and</strong> cause considerable distress to the sufferer, are not<br />

uncommon <strong>and</strong> can also be addressed by the noble daffodil. Physiological erectile<br />

impotence has been the subject of much recent research <strong>and</strong> has led to effective, if<br />

presently expensive, therapies. However, the use of galanthamine for erectile<br />

dysfunction due to physiological causes secondary to other disease states, disorders<br />

of the urogenital or endocrine systems, due to drug therapy (e.g., anti-hypertensives,<br />

anti-depressant <strong>and</strong> anti-psychotic drugs) or related to psychiatric problems, has<br />

been advocated (Katz, 1993). In addition, the Japanese patent that advocates the<br />

use of crude extracts of plants, such as Lamium album, Sesamum indicum <strong>and</strong><br />

<strong>Narcissus</strong> tazetta, together with a number of fatty acids <strong>and</strong> surfactants to improve<br />

humectant properties, elasticity <strong>and</strong> smoothness of ageing skin would add to the<br />

surmise that daffodils could provide means of addressing the failings of advancing<br />

years (Taisho Pharm Co. Ltd., 1993). In any event, strong pharmacological<br />

reasoning, if backed by effective clinical studies, could well mean that the <strong>Narcissus</strong><br />

genus will play an important role in medical <strong>and</strong> cosmetic practice well into the<br />

new millennium.<br />

REFERENCES<br />

Abdusamatov, A. (1963) Methylapogalanthamine hydrochloride. Soviet Union Patent No. 227,526.<br />

Afanasev, V.V. <strong>and</strong> Lukin, V.A. (1993) Treatment of acute poisoning with di:phenylhydramine.<br />

Russian Patent No. 1,722,499.<br />

Aleks<strong>and</strong>rova, I.V., Gordonora, I.K. <strong>and</strong> Tulakin, V.G. (1994) Strain of cultivable ungernia<br />

victoris U-I cells. Russian Patent No. 1,806,188.<br />

Asmussen, B., Hoffman, H. <strong>and</strong> Muller, W. (1997) Recovering active from unused or discarded<br />

applications <strong>and</strong> production waste. German Patent No. 19,524,083.<br />

Asoyeva, E.Z. (1963) Galanthamine production. Soviet Union Patent No. 162,634.<br />

Asoyeva, E.Z. (1968) Galanthamine. Soviet Union Patent No. 186,493.<br />

Bannister, R.M. <strong>and</strong> McCague, R. (1997) Production of galanthamine derivatives using secondary<br />

amine precursor. International Patent No. WO 97/11,078.<br />

Birch, N., Gatehouse, A.M.R., Geoghegan, I. <strong>and</strong> Robertson, W. (1995) Control of nematodes,<br />

particularly in plants. International Patent No. WO 95/26,634.<br />

Bogdanov, O.V., Losev, N.A. <strong>and</strong> Shaitor, V.M. (1984) Treating spastic forms of cerebral<br />

paralysis in children. Soviet Union Patent No. 1,438,799.<br />

Callahan, M.J. <strong>and</strong> Schwarz, R.D. (1999) Composition used for treating central <strong>and</strong> peripheral<br />

nervous system disorders. International Patent No. WO 98/30,243.

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