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B O O K - American College of Rheumatology

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ACR Study Groups<br />

1:00 - 2:00 PM<br />

B309<br />

Capillaroscopy in Rheumatic Diseases<br />

Moderators: Maurizio E. Cutolo, MD; University <strong>of</strong> Genova;<br />

Genova, Italy<br />

Ariane L. Herrick, MD; Rheumatic Diseases Centre; Trust Salford,<br />

United Kingdom<br />

1:00 PM<br />

Introduction with Brief History <strong>of</strong> Capillaroscopy<br />

Maurizio E. Cutolo, MD; University <strong>of</strong> Genova; Genova, Italy<br />

1:05 PM<br />

The Technique <strong>of</strong> Videocapillaroscopy<br />

Alberto Sulli, MD; University <strong>of</strong> Genoa, Italy<br />

1:20 PM<br />

Quantification <strong>of</strong> Microcirculatory Abnormalities using<br />

Capillaroscopy<br />

Ariane L. Herrick, MD; Rheumatic Diseases Centre; Trust Salford,<br />

United Kingdom<br />

1:30 PM<br />

Capillaroscopic Patterns: From Normal to Pathologic<br />

Maurizio E. Cutolo, MD; University <strong>of</strong> Genova; Genova, Italy<br />

1:40 PM<br />

Discussion<br />

1:45 PM<br />

Practical ‘Live’ Demonstration <strong>of</strong> Videocapillaroscopy<br />

Ariane L. Herrick, MD; Rheumatic Diseases Centre; Trust Salford,<br />

United Kingdom<br />

Maurizio E. Cutolo, MD; University <strong>of</strong> Genova; Genova, Italy<br />

Session Overview:<br />

Nailfold capillaroscopy provides a unique and noninvasive/<br />

safe window into the microcirculation, and abnormal nailfold<br />

capillaries are highly predictive <strong>of</strong> an underlying connective<br />

tissue disorder. Typical changes include widened capillaries<br />

and areas <strong>of</strong> avascularity. Recent advances in capillaroscopy,<br />

including videocapillaroscopy (which allows high magnification)<br />

and computerised s<strong>of</strong>tware, are revitalizing interest in<br />

capillaroscopy amongst rheumatologists. The ability to<br />

quantify abnormality means that capillaroscopy has the<br />

potential <strong>of</strong> becoming an early diagnostic tool and biomarker<br />

in scleroderma-spectrum disorders. A study group will inform<br />

attendees <strong>of</strong> these advances and stimulate the international<br />

dialogue necessary to standardize techniques and further<br />

broaden their clinical application.<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• discuss advantages and disadvantages <strong>of</strong> different<br />

capillaroscopy methods (dermoscopy, widefield<br />

capillaroscopy, videocapillaroscopy)<br />

• describe major capillaroscopic abnormalities suggestive <strong>of</strong> a<br />

scleroderma-spectrum disorder and score them<br />

• identify current and future clinical and research applications<br />

B308<br />

Childhood Vasculitis<br />

Moderators: Susanne M. Benseler, MD, PhD; The Hospital for<br />

Sick Children; Toronto, ON, Canada<br />

David A. Cabral, MBBS; British Columbia Children’s Hospital;<br />

Vancouver, BC, Canada<br />

1:00 PM<br />

Novel Approaches to Classifying Systemic Childhood Vasculitis<br />

David A. Cabral, MBBS; BC Children’s Hospital; Vancouver, BC,<br />

Canada<br />

1:15 PM<br />

Novel Biomarkers <strong>of</strong> Childhood Vasculitis<br />

Paul Brogan, BSc, MBCHB, PhD; <strong>Rheumatology</strong> Unit, Institute <strong>of</strong><br />

Child Health; London<br />

1:30 PM<br />

Disease Activity in Childhood Vasculitis<br />

Pavla Dolezalova, MD; 1st Faculty <strong>of</strong> Medicine and General<br />

Faculty Hospital; Praha, Czech Republic<br />

1:45 PM<br />

Measurement and Study Conduct in Childhood Vasculitis<br />

Raashid Luqmani, DM; Nuffield Department <strong>of</strong> Orthopaedics,<br />

<strong>Rheumatology</strong> and Musculoskeletal Sciences; Oxford, United<br />

Kingdom<br />

Session Overview:<br />

Successful international collaboration and the development<br />

<strong>of</strong> innovative, web-based data collection tools have recently<br />

advanced the field <strong>of</strong> childhood vasculitis. The international<br />

pediatric vasculitis investigator network was established,<br />

which is currently conducting important studies aiming to<br />

enhance disease recognition, validate classification proposals,<br />

develop and validate measures <strong>of</strong> disease activity and damage,<br />

standardize treatment protocols and ultimately improve the<br />

outcome <strong>of</strong> children with vasculitis worldwide. The study group<br />

application aims to formalize the strong association <strong>of</strong> the<br />

investigators with the ACR. The focus <strong>of</strong> the first study group<br />

session is classification and diagnostic challenges <strong>of</strong> childhood<br />

vasculitis.<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• recognize distinct entities in the spectrum <strong>of</strong> childhood<br />

vasculitis<br />

• classify pediatric vasculitis patients based on the newly<br />

validated classification system<br />

• identify novel biomarkers <strong>of</strong> childhood vasculitis<br />

• assess disease activity <strong>of</strong> pediatric vasculitis patients using the<br />

novel PVAS tool<br />

B311<br />

Clinical Research Methodology<br />

Moderator: Theodore Pincus, MD; New York University Hospital<br />

for Joint Disease; Hastings-on-Hudson, NY<br />

1:00 PM<br />

Improved Outcome Criteria for Rheumatic Diseases: The Role<br />

<strong>of</strong> IRT and CAT<br />

James F. Fries, MD; Stanford University Medical Center; Palo<br />

Alto, CA<br />

1:20 PM<br />

Diagnostic Criteria for Rheumatoid Arthritis - The New and The<br />

Old<br />

Yusuf Yazici, MD; Hospital for Joint Diseases; Hastings on<br />

Hudson, NY<br />

2010 Program Book 107<br />

wednesday

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