B O O K - American College of Rheumatology
B O O K - American College of Rheumatology
B O O K - American College of Rheumatology
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ACR Study Groups<br />
1:00 - 2:00 PM<br />
B309<br />
Capillaroscopy in Rheumatic Diseases<br />
Moderators: Maurizio E. Cutolo, MD; University <strong>of</strong> Genova;<br />
Genova, Italy<br />
Ariane L. Herrick, MD; Rheumatic Diseases Centre; Trust Salford,<br />
United Kingdom<br />
1:00 PM<br />
Introduction with Brief History <strong>of</strong> Capillaroscopy<br />
Maurizio E. Cutolo, MD; University <strong>of</strong> Genova; Genova, Italy<br />
1:05 PM<br />
The Technique <strong>of</strong> Videocapillaroscopy<br />
Alberto Sulli, MD; University <strong>of</strong> Genoa, Italy<br />
1:20 PM<br />
Quantification <strong>of</strong> Microcirculatory Abnormalities using<br />
Capillaroscopy<br />
Ariane L. Herrick, MD; Rheumatic Diseases Centre; Trust Salford,<br />
United Kingdom<br />
1:30 PM<br />
Capillaroscopic Patterns: From Normal to Pathologic<br />
Maurizio E. Cutolo, MD; University <strong>of</strong> Genova; Genova, Italy<br />
1:40 PM<br />
Discussion<br />
1:45 PM<br />
Practical ‘Live’ Demonstration <strong>of</strong> Videocapillaroscopy<br />
Ariane L. Herrick, MD; Rheumatic Diseases Centre; Trust Salford,<br />
United Kingdom<br />
Maurizio E. Cutolo, MD; University <strong>of</strong> Genova; Genova, Italy<br />
Session Overview:<br />
Nailfold capillaroscopy provides a unique and noninvasive/<br />
safe window into the microcirculation, and abnormal nailfold<br />
capillaries are highly predictive <strong>of</strong> an underlying connective<br />
tissue disorder. Typical changes include widened capillaries<br />
and areas <strong>of</strong> avascularity. Recent advances in capillaroscopy,<br />
including videocapillaroscopy (which allows high magnification)<br />
and computerised s<strong>of</strong>tware, are revitalizing interest in<br />
capillaroscopy amongst rheumatologists. The ability to<br />
quantify abnormality means that capillaroscopy has the<br />
potential <strong>of</strong> becoming an early diagnostic tool and biomarker<br />
in scleroderma-spectrum disorders. A study group will inform<br />
attendees <strong>of</strong> these advances and stimulate the international<br />
dialogue necessary to standardize techniques and further<br />
broaden their clinical application.<br />
Upon completion <strong>of</strong> this session, participants should be able to:<br />
• discuss advantages and disadvantages <strong>of</strong> different<br />
capillaroscopy methods (dermoscopy, widefield<br />
capillaroscopy, videocapillaroscopy)<br />
• describe major capillaroscopic abnormalities suggestive <strong>of</strong> a<br />
scleroderma-spectrum disorder and score them<br />
• identify current and future clinical and research applications<br />
B308<br />
Childhood Vasculitis<br />
Moderators: Susanne M. Benseler, MD, PhD; The Hospital for<br />
Sick Children; Toronto, ON, Canada<br />
David A. Cabral, MBBS; British Columbia Children’s Hospital;<br />
Vancouver, BC, Canada<br />
1:00 PM<br />
Novel Approaches to Classifying Systemic Childhood Vasculitis<br />
David A. Cabral, MBBS; BC Children’s Hospital; Vancouver, BC,<br />
Canada<br />
1:15 PM<br />
Novel Biomarkers <strong>of</strong> Childhood Vasculitis<br />
Paul Brogan, BSc, MBCHB, PhD; <strong>Rheumatology</strong> Unit, Institute <strong>of</strong><br />
Child Health; London<br />
1:30 PM<br />
Disease Activity in Childhood Vasculitis<br />
Pavla Dolezalova, MD; 1st Faculty <strong>of</strong> Medicine and General<br />
Faculty Hospital; Praha, Czech Republic<br />
1:45 PM<br />
Measurement and Study Conduct in Childhood Vasculitis<br />
Raashid Luqmani, DM; Nuffield Department <strong>of</strong> Orthopaedics,<br />
<strong>Rheumatology</strong> and Musculoskeletal Sciences; Oxford, United<br />
Kingdom<br />
Session Overview:<br />
Successful international collaboration and the development<br />
<strong>of</strong> innovative, web-based data collection tools have recently<br />
advanced the field <strong>of</strong> childhood vasculitis. The international<br />
pediatric vasculitis investigator network was established,<br />
which is currently conducting important studies aiming to<br />
enhance disease recognition, validate classification proposals,<br />
develop and validate measures <strong>of</strong> disease activity and damage,<br />
standardize treatment protocols and ultimately improve the<br />
outcome <strong>of</strong> children with vasculitis worldwide. The study group<br />
application aims to formalize the strong association <strong>of</strong> the<br />
investigators with the ACR. The focus <strong>of</strong> the first study group<br />
session is classification and diagnostic challenges <strong>of</strong> childhood<br />
vasculitis.<br />
Upon completion <strong>of</strong> this session, participants should be able to:<br />
• recognize distinct entities in the spectrum <strong>of</strong> childhood<br />
vasculitis<br />
• classify pediatric vasculitis patients based on the newly<br />
validated classification system<br />
• identify novel biomarkers <strong>of</strong> childhood vasculitis<br />
• assess disease activity <strong>of</strong> pediatric vasculitis patients using the<br />
novel PVAS tool<br />
B311<br />
Clinical Research Methodology<br />
Moderator: Theodore Pincus, MD; New York University Hospital<br />
for Joint Disease; Hastings-on-Hudson, NY<br />
1:00 PM<br />
Improved Outcome Criteria for Rheumatic Diseases: The Role<br />
<strong>of</strong> IRT and CAT<br />
James F. Fries, MD; Stanford University Medical Center; Palo<br />
Alto, CA<br />
1:20 PM<br />
Diagnostic Criteria for Rheumatoid Arthritis - The New and The<br />
Old<br />
Yusuf Yazici, MD; Hospital for Joint Diseases; Hastings on<br />
Hudson, NY<br />
2010 Program Book 107<br />
wednesday