B O O K - American College of Rheumatology

Upon completion of this session, participants should be able to:
• describe unique and challenging diagnostic dilemmas
• discuss the differential diagnosis
• review methods used to identify the underlying diagnosis
ACR Concurrent Abstract Sessions
2:30 – 4:00 PM
3:30 PM
1360. Apolipoprotein E Receptor (apoER2) Is Involved
for Thrombotic Complications in a Murine Model of
Antiphospholipid Syndrome.
Z. Romay Penabad 1 , T. Shilagard 1 , G. Vargas 1 , R. Aguilar
-Valenzuela 1 , P. de Groot 2 and S. Pierangeli 1 , 1 Univ of TX Med
Branch, Galveston, TX, 2 University Hospital Utrecht, Utretch, The
Netherlands
tuesday
A402
Antiphospholipid Syndrome I
Moderators: Pojen P. Chen, PhD; University of California-Los
Angeles School of Medicine; Los Angeles, CA
Robert A.S. Roubey, MD; University of North Carolina; Chapel
Hill, NC
2:30 PM
1356. TLR-4 and Annexin A2 Involvement in Endothelial Cell
Activation by Anti-Phospholipid Antibodies: Specific Silencing
by Small Interfering RNAs.
Elena Raschi 2 , Valentina Broggini 3 , Maria Orietta Borghi 4 , Claudia
Grossi 2 and Pierluigi Meroni 1 , 1Instituto G. Pini University,
Milano, Italy, 2 IRCCS Istituto Auxologico Italiano, Milan, Italy,
3
University of Milan, Italy, 4 University of Milan; IRCCS Istituto
Auxologico Italiano, Milan, Italy
2:45 PM
1357. Role of Reactive Oxigen Species and ROS-Dependent
Downstream Signalling in the Prothrombotic State Elicited by
Antiphospholipid Antibodies from Primary Antiphospholipid
Syndrome Patients.
Chary Lopez-Pedrera 1 , Patricia Ruiz-Limon 1 , Maria Angeles
Aguirre 1 , Nuria Barbarroja 1 , Antonio Rodriguez-Ariza 1 , Carlos
Perez-Sanchez 1 , Eduardo Collantes-Estevez 1 , Jose Manuel
Villalba 4 , Francisco Velasco 1 , Munther A. Khamashta 2 and Maria
Jose Cuadrado 3 , 1Reina Sofia Hospital-IMIBIC, Cordoba, Spain,
2
The Rayne Institute, London, United Kingdom, 3 The Rayne
Institute, London, United Kingdom, 4 University of Cordoba,
Cordoba, Spain
3:00 PM
1358. Peptide & NMR Spectroscopy Studies of Recombinant
Domain I Confirm Conformationally Correct Domain I and
Non-Linear Epitope Binding to Anti-Domain I Antiphospholipid
Antibodies.
Charis Pericleous 2 , Toluwape Disu 4 , Jennifer Miles 1 , Diego
Esposito 1 , Acely Garza-Garcia 1 , Paul C. Driscoll 1 , David S.
Latchman 4 , David A. Isenberg 3 , Ian Giles 4 , Anisur Rahman 4
and Yiannis Ioannou 4 , 1 National Institute of Medical Research,
London, UK, 2 University College London, London, United
Kingdom, 3 University College London, London, United Kingdom,
4
University College London, London, UK
3:45 PM
1361. C6-Deficient Mice Are Protected from the Pathogenic
Effects of Antiphospholipid Antibodies.
A. L. Carrera-Marin, R. Aguilar-Valenzuela, Z. Romay Penabad, E.
Papalardo and S. Pierangeli, Univ of TX Med Branch, Galveston,
TX
A410
Epidemiology and Health Services Research: Gout
Moderators: Lisa G. Suter, MD; Yale University; New Haven, CT
Jeffrey R. Curtis, MD, MPH; University of Alabama - Birmingham;
Birmingham, AL
2:30 PM
1362. Short-Term Effects of Caffeinated Beverage Intake on Risk
of Recurrent Gout Attacks.
Tuhina Neogi 1 , Clara Chen 3 , Christine Chaisson 3 , David J. Hunter 4
and Yuqing Zhang 2 , 1 Boston Univ Schl of Med, Boston, MA,
2
Boston Univ School of Medicine, Boston, MA, 3 Boston Univ
School of Medicine, 4 University of Sydney, Boston, MA
2:45 PM
1363. Prevalence of Hyperuricemia in the US General
Population: The National Health and Nutrition Examination
Survey (NHANES) 1999-2008.
Yanyan Zhu 1 , Bhavik Pandya 2 and Hyon Choi 1 , 1 Boston University
of School of Medicine, Boston, MA, 2 Takeda Pharmaceuticals
International, Inc, Deerfield, IL
3:00 PM
1364. Obesity Is Associated with a Younger Age at Gout
Incidence.
Mara A. McAdams 4 , Janet W. Maynard 2 , Judith A. Bolton
Hoffman 4 , Alan N. Baer 3 , Allan C. Gelber 1 and Josef Coresh 4 ,
1
Baltimore, MD, 2 Johns Hopkins Univ, Baltimore, MD, 3 Johns
Hopkins University, Baltimore, MD, 4 Johns Hopkins, Bloomberg
School of Public Health
3:15 PM
1365. Health Related Quality of Life (HRQOL) in Tophaceous vs.
Non-Tophaceous Gout.
Puja Khanna 2 , Jay Persselin 3 , Ron Hays 1 , Daniel Furst 1 , Harold
Paulus 1 , Paul Maranian 1 and Dinesh Khanna 1 , 1UCLA, 2 UCLA and
West LA VA, 3 West LA VA
3:15 PM
1359. A Novel, Simple Fluid Phase Binding Assay for the
Detection of Serum Anti-Domain I Antibodies in Patients with
the Antiphospholipid Syndrome.
Charis Pericleous 2 , Acely Garza-Garcia 1 , Paul C. Driscoll 1 , David
S. Latchman 4 , David A. Isenberg 3 , Ian P. Giles 4 , Anisur Rahman 4
and Yiannis Ioannou 4 , 1National Institute of Medical Research,
London, UK, 2 University College London, London, United
Kingdom, 3 University College London, London, United Kingdom,
4
University College London, London, UK
3:30 PM
1366. Cherry Consumption and Risk of Recurrent Gout Attacks.
Yuqing Zhang 3 , Clara Chen 1 , David J. Hunter 4 , Christine E.
Chaisson 1 , Hyon K. Choi 5 and Tuhina Neogi 2 , 1Boston Univ
Medical Ctr, Boston, MA, 2 Boston Univ Schl of Med, Boston,
MA, 3 Boston Univ School of Medicine, Boston, MA, 4 Sydney
University, Sydney, Australia, 5 Univ of British Columbia,
Vancouver, BC, Canada
70
2010 Program Book