B O O K - American College of Rheumatology

ACR Poster Session B
752. The Effects of the Anti-CD22 Monoclonal Antibody
Epratuzumab on Peripheral Blood B Cells and Immune
Responses In Vivo, and Immunoglobulin Production In Vitro.
Anthony Shock 1 , Derek Brown 2 , Kenneth Crook 2 , Stevan Shaw 2 ,
Timothy Bourne 2 , Roland Foulkes 2 and Geoffrey Rose 2 , 1 UCB,
Slough, Berkshire, Slough, United Kingdom, 2 UCB, Slough,
Berkshire, UK.
753. TNF Blockade Impairs the Induction of T-Cell Dependent
Antibody Responses. Gabriela Franco Salinas 1 , Leen De Rycke 2 ,
Sophie Brouard 4 , Vojislav Jovanovic 4 , Frederique Moizant 4 ,
Tineke Cantaert 2 , Mirjam van der Burg 3 , Barbara Barendregt 3 ,
Paul Peter Tak 2 , Jean-Paul Soulillou 4 and Dominique Baeten 2 ,
1
Academisch Medisch Centrum, University of Amsterdam,
Amsterdam, Noord Holland, The Netherlands, 2 Academisch
Medisch Centrum, University of Amsterdam, Amsterdam, The
Netherlands, 3 Immunology, Erasmus Medical Center, Rotterdam,
Netherlands, 4 Institut de Transplantation et Recherche en
Transplantation, INSERM U 643 , Nantes, France.
Epidemiology and Health Services Research: MSK, CTD and SLE
754. A Systematic Literature Review of the Direct Costs of
Systemic Lupus Erythematosus (SLE) in the United States
(US). Katherine A. Slawsky 1 , Ancilla Fernandes 2 , Susan Manzi 3 ,
Lauren Fusfeld 1 and Thomas F. Goss 1 , 1 Boston Healthcare
Associates, Inc., Boston MA and Washington DC, 2 MedImmune
LLC, Gaithersburg, MD, 3 West Penn Allegheny Health System,
Pittsburgh, PA.
755. A Systematic Review To Appraise the Quality of Cost-
Effectiveness Studies of Biologic Agents for the Treatment
of Rheumatoid Arthritis. Maria A. Lopez-Olivo 1 , Yomei Shaw 2
and Maria E. Suarez-Almazor 3 , 1 The University of Texas M.D.
Anderson Cancer Center, Houston, TX, 2 The University of
Texas M.D. Anderson Cancer Center, 3 University of Texas, MD
Anderson Cancer Center, Houston, TX.
756. Agreement between Tuberculin Skin Test and Interferon-Assay
in Korean Patients with Rheumatoid Arthritis and Ankylosing
Spondylitis before Initiation of Anti-Tumor Necrosis Factor
Therapy. Yong-Geun Jeong 1 , Ji-Min Kim 3 , Su-Jin Moon 3 , Seung-Ki
Kwok 3 , Ji-Hyeon Ju 3 , Kyung-Su Park 3 , Sung-Hwan Park 2 and Ho-
Youn Kim 1 , 1 Seoul St. Mary’s Hospital, The Catholic University of
Korea, Seoul, Republic of Korea, 2 Seoul St. Mary’s Hospital, The
Catholic University of Korea, Seoul, Korea, Republic of, 3 Seoul St.
Mary’s Hospital, The Catholic University of Korea, Seoul, South
Korea.
757. Assessing Systemic Lupus Erythematosus Disease Severity and
Disease Flares: Development of a Claims-Based Algorithm.
Cindy P. Garris 2 , Priti M. Jhingran 2 , Nicole M. Engel-Nitz 4 , Aylin
A. Riedel 5 , George Goldberg 4 , Damon L. Bass 1 and Gregory J.
Dennis 3 , 1 GlaxoSmithKline, King of Prussia, PA, 2 GlaxoSmithKline,
Research Triangle Park, NC, 3 Human Genome Sciences,
Rockville, MD, 4 i 3 Innovus, Eden Prarie, MN, 5 i 3 Innovus, Eden
Prarie, NC.
758. Colonization and Infection by Staphylococcus Aureus among
Those Using Biologic Therapy. Cara Varley 1 , Atul A. Deodhar 1 ,
Benjamin Ehst 1 , Antony Bakke 1 , Andrew Blauvelt 1 , Robert Vega 2
and Kevin Winthrop 1 , 1 Oregon Health & Science University,
Portland, OR, 2 Oregon State Public Health Laboratory, Hillsboro,
OR.
759. Comprehensive Health Economic Assessment of Sequenced
Treatment with Biologics in Moderate-to-Severe Rheumatoid
Arthritis: Analysis Based on ACR50 and ACR70 Responses.
Erkki J. O. Soini 1 , Taru A. Hallinen 1 , Markku J. Kauppi 3 , Ville
Vihervaara 4 and Kari Puolakka 2 , 1 ESiOR Oy, Kuopio, Finland,
2
Lappeenranta Central Hospital, Lappeenranta, Finland,
3
Päijät-Häme Central Hospital, Lahti, Finland, 4 Roche Oy, Espoo,
Finland.
760. Correlations between 3 Work-Related Patient-Reported
Outcome Instruments for Patients with Ankylosing Spondylitis.
Annelies Boonen 2 , Walter P. Maksymowych 3 , Sumati Rao 1 ,
Naijun Chen 1 and Mary Cifaldi 1 , 1 Abbott Laboratories,
Abbott Park, IL, 2 University Hospital Maastricht, Maastricht,
Netherlands, 3 University of Alberta, Edmonton, AB.
761. Costs for Health Care, Prescribed Drugs, and Sick Leave Differ
for Patients with Different Types of Spondylarthropathy. Ann
B. I. Bremander 1 , Aleksandra Turkiewicz 2 , Martin Englund 2 ,
Emma Haglund 3 , Gisela Kobelt 2 , Ingemar F. Petersson 2 and
Britta Strömbeck 2 , 1 Musculoskeletal Research Center, Dept. of
Orthopedics, Clinical Sciences, Lund University, Lund, Research
and Development Cente at Spenshult Hospital for Rheumatic
Diseases, Oskarstrom, Sweden, 2 Musculoskeletal Research
Center, Dept. of Orthopedics, Clinical Sciences, Lund University,
Lund, Sweden, 3 Musculoskeletal Research Center, Dept. of
Orthopedics, Clinical Sciences, Lund University, Lund, Sweden,
Research and Development Cente at Spenshult Hospital for
Rheumatic Diseases, Halmstad, Sweden.
762. Dietary Intake of Vitamin D during Adolescence and Risk of
Adult Onset Systemic Lupus Erythematosus and Rheumatoid
Arthritis. Linda T. Hiraki 3 , Karen H. Costenbader 1 , Kassandra
Munger 4 and Elizabeth W. Karlson 2 , 1 Brigham & Women, Boston,
MA, 2 Brigham and Womens Hospital, Boston, MA, 3 Harvard
School of Public Health, Boston, MA, 4 Harvard School of Public
Health.
763. Direct and Indirect Costs of Spondlyoarthritis Patients Preand
Post-Diagnosis. Noam Kirson 2 , Howard Birnbaum 2 , Sumati
Rao 1 , Elyse Swallow 2 , Tracy Waldman 2 , Elias Dayoub 2 and Mary
Cifaldi 1 , 1 Abbott Laboratories, Abbott Park, IL, 2 Analysis Group,
Inc., Boston, MA.
764. Distinguishing Levels of Disease Flare in Patients with Systemic
Lupus Erythematosus Using Administrative Claims Data.
Nicole Engel-Nitz 5 , James Burke 5 , Cindy P. Garris 3 , Priti Jhingran 1 ,
Damon L. Bass 2 and Gregory J. Dennis 4 , 1 GlaxoSmithKline,
2
GlaxoSmithKline, King of Prussia, PA, 3 GlaxoSmithKline, RTP, NC,
4
Human Genome Sciences, 5 i 3 Innovus.
765. Does Cigarette Smoking Affect Disease Phenotype in Systemic
Lupus Erythematosus. Meenakshi Jolly 2 , Rachel A. Mikolaitis 4 ,
Joel A. Block 4 and Michelle Petri 1 , 1 John Hopkins University,
2
Rush University Medical Center, Chicago, IL, 3 Rush University
Medical Center, Chicago, IL, 4 Rush University Medical Center.
766. Early and Persistent Clinical Remission Reduces Long-Term
Disability in Inflammatory Polyarthritis: Results from the
Norfolk Arthritis Register. Carlo Alberto Scirè 2 , Suzanne M.
Verstappen 1 , Hoda Mjriafari 1 , Diane Bunn 3 , Mark Lunt 1 , Ian
Bruce 1 , Carlomaurizio Montecucco 2 and Deborah P. Symmons 4 ,
1
Arthritis Research UK Epidemiology Unit, Stopford Building,
The University of Manchester, Manchester, United Kingdom,
2
Department of Rheumatology, IRCCS Policlinico San Matteo
Foundation, University of Pavia, Pavia, Italy, 3 Norfolk Arthritis
Register, Norfolk and Norwich University Hospital, Norwich,
United Kingdom., 4 Univ of Manchester, Manchester, United
Kingdom.
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2010 Program Book