B O O K - American College of Rheumatology

ACR Poster Session B
hiroshima Memorial Hospital, Higashihiroshima, Japan, 2 Inoue
Hospital, Takasaki, Japan, 3 Izumihara Rheumatic and Medical
Clinic, Kagoshima, Japan, 4 Katayama Orthopedic Reumatology
Clonic, Asahikawa, Japan, 5 Matsubara Mayflower Hospital,
Kato, Japan, 6 Matsubara Mayflower Hospital, Kato, Japan,
7
Matsuno Clinic for Rheumatic Diseases, Toyama, Japan, 8 Oribe
Rheumatism and Internal Medicine Clinic, Oita, Japan, 9 PS Clinic,
Fukuoka, Japan, 10 Research Institute of Joint Diseases, Kobe,
Japan, 11 Sagawa Akira Rheumatology Clinic, Sapporo, Japan,
12
Shono Rheumatology Clinic, Fukuoka, Japan, 13 Tsuchida Clinic,
Chiba, Japan.
Systemic Lupus Erythematosus - Clinical Aspects and Treatment II
1139. 1α,25-Dihydroxyvitamin D3 Suppresses Differentiation,
Maturation and Activation of Dendritic Cells from Patients
with Systemic Lupus Erythematosus. Hai Jing Wu, Chak Sing
Lau and Mo Yin Mok, The University of Hong Kong, Queen Mary
Hospital, Hong Kong.
1140. 30-Year Follow-Up of Lupus Nephritis in a Single Clinic –
Outcome, Serology and Ethnicity. Sara C. Croca 2 , Teresa
Rodrigues 1 and David A. Isenberg 3 , 1 Faculdade de Medicina
de Lisboa, Laboratory of Biomathematics, Lisboa, Portugal,
2
Hospital de Santa Maria, Department of Medicine 1 , Lisboa,
Portugal, 3 UCL Div of Medicine, London, United Kingdom.
1141. A Flow Cytometric Receptor Occupancy Assay Demonstrates
Dose-Dependent Blockade of B7RP-1 by AMG 557 on
Circulating B Cells from SLE Subjects. Barbara A. Sullivan 1 ,
Cherie L. Green 2 , Ming Zhang 1 , Christina Abbott 1 , Shelley
Belouski 1 , John Thomas 1 , Kevin Gorski 1 , Gerald Siu 3 , James B.
Chung 1 and John Ferbas 1 , 1 Amgen, Thousand Oaks, CA, United
Kingdom, 2 Amgen, Thousand Oaks, CA, 3 GlaxoSmithKline,
Stevenage, United Kingdom.
1142. A Longitudinal Study of the Prolongation of the Corrected QT
Interval in Anti-Ro/SSA Positive Adults with Systemic Lupus
Erythematosus. Josiane Bourré-Tessier 3 , Thao Huynh 5 , Ann E.
Clarke 4 , Sasha R. Bernatsky 1 , Lawrence Joseph 3 , Patrick Belisle 3
and Christian A. Pineau 2 , 1 McGill UHC/RVH, Montreal, QC,
Canada, 2 McGill Univ Health Center, Montreal, QC, Canada,
3
McGill University, 4 Montreal General Hospital, Montreal, QC,
Canada, 5 Montreal General Hospital.
1143. Allogeneic Mesenchymal Stem Cells Transplantation in Severe
and Refractory Systemic Lupus Erythematosus. Lingyun Sun 1 ,
Dandan Wang 1 , Huayong Zhang 1 , Jun Liang 1 , Xuebing Feng 1 and
Yayi Hou 2 , 1 Department of Rheumatology and Immunology, The
Affiliated Drum Tower Hospital of Nanjing University Medical
School, 2 Immunology Laboratory, Nanjing University Medical
School.
1144. Analysis of the Use of Rituximab in the Treatment of Lupus
Nephritis. Sara C. Croca 1 and David A. Isenberg 2 , 1 Hospital de
Santa Maria, Department of Medicine 1 , Lisbon, Portugal, 2 UCL
Div of Medicine, London, United Kingdom.
1145. Anti-Mullerian Hormone in Systemic Lupus Erythematodes
– Is Fertility Affected? Joerg C. Henes 1 , Melanie Henes 4 ,
Tanja Fehm 4 , Diethelm Wallwiener 4 , Lothar Kanz 2 , Ina
Koetter 2 and Barbara Lawrenz 3 , 1 Department for Internal
Medicine II; University Hospital Tuebingen, Tuebingen,
Germany, 2 Department for Internal Medicine II; University
Hospital Tuebingen, Germany, 3 Department of Gynecology
and Obstetrics; University Hospital of Tuebingen, Germany,
4
Department of Gynecology and Obstetrics; University Hospital
Tuebingen, Germany.
1146. Belimumab, a BLyS-Specific Inhibitor, Significantly Reduced
Autoantibodies, Normalized Low Complement, and Reduced
Selected B-Cell Populations in Patients with Seropositive
Systemic Lupus Erythematosus (SLE): The Phase 3 BLISS
Studies. W. Stohl 12 , F. Hiepe 1 , M. Thomas 8 , M. A. Scheinberg 2 ,
A. E. Clarke 9 , C. Aranow 10 , R. Jimenez 4 , F. Wellborne 5 , C. Abud-
Mendoza 3 , D. Hough 6 , L. Pineda 7 , T. S. Migone 7 , W. Freimuth 7 , W.
W. Chatham 11 and on Behalf of the BLISS- 52 and - 76 Study Groups,
1
Charité Universitätsmedizin, Berlin, Germany, 2 Hospital Abreu
Sodré Pesquisa Clínica, Sao Paulo, SP, Brazil, 3 Hospital Central
y Facultad de Medicina, San Luis Potosi, Mexico, 4 Hospital G.
Fricke, Vina del Mar, Vina del Mar, Chile, 5 Houston Institute
for Clinical Research, Houston, TX, 6 Human Genome Sciences,
Inc, Rockville, MD, 7 Human Genome Sciences, Inc, Rockville,
Rockville, MD, 8 Kerala Institute of Medical Sciences, Trivandrum,
India, 9 McGill University Health Centre, The Montreal General
Hospital, Montreal, QC, Canada, 10 The Feinstein Institute for
Medical Research, Manhasset, Manhasset, NY, 11 UAB Arthritis
Clinical Intervention Program, Birmingham, AL, 12 USC Keck
School of Medicine, Los Angeles, CA.
1147. Comparison of Serum Free Light Chains, Interferon and
Interleukins as Biomarkers of Disease Activity in Systemic
Lupus Erythematosus (SLE). Serene Francis 4 , Rohit Aggarwal 6 ,
Rachel Mikolaitis 4 , Timothy B. Niewold 5 , Susanna Chubinskaya 4 ,
Joel A. Block 1 , Winston Sequeira 2 and Meenakshi Jolly 3 , 1 Rush
University Medical Center, Chicago, IL, 2 Rush University Medical
Center, Chicago, IL, 3 Rush University Medical Center, Section
of Rheumatology, Chicago, IL, 4 Rush University Medical Center,
Section of Rheumatology, 5 University of Chicago, Section of
Rheumatology, Chicago, IL, 6 University of Pittsburgh Medical
Center.
1148. Coronary Calcification in SLE: Comparison with Multi-Ethnic
Study of Atherosclerosis (MESA). Adnan N. Kiani 3 , Wendy Post 4 ,
Moyses Szklo 2 , Joan M. Bathon 4 , Laurence S. Magder 6 , Russell
Tracy 8 , Pamela Schreiner 7 , Daniel O’Leary 5 and Michelle A.
Petri 1 , 1 Timonium, MD, 2 Johns Hopkins University, Department
of Epidemiology, 3 Johns Hopkins University, School of Medicine,
Baltimore, MD, 4 Johns Hopkins University, School of Medicine,
5
Tufts University, 6 University of Maryland, 7 University of
Minnesota, 8 University of Vermont.
1149. Decrease in Complement (C3) Levels during Systemic Lupus
Erythematosus Pregnancy Is Associated with Higher Rates of
Pre-Eclampsia. Aisha Lateef 2 , Laurence S. Magder 3 and Michelle
A. Petri 1 , 1 Johns Hopkins Lupus Center, School of Medicine,
Johns Hopkins University, Timonium, MD, 2 National University
Health System, Singapore, Singapore, 3 University of Maryland
Medical School, Baltimore, MD.
1150. Dendritic Cells and Regulatory T CD4+CD25Bright in Pregnant
Patients with Systemic Lupus Erythematosus. Luis J. Jara 1 ,
Griselda Teresa Romero-Sánchez 1 , Laura A. Montiel-Cervantes 1 ,
Gabriela Medina 1 , Polita Cruz-Cruz 2 , Jorge Vela-Ojeda 1 , Rafael
Arias-Flores 1 , Olga Vera-Lastra 1 and Miguel A. Saavedra Salinas 1 ,
1
Hospital de Especialidades Centro Medico La Raza, IMSS,
Mexico City, DF, Mexico, 2 Hospital de Gineco-Obstetricia No. 3 ,
Centro Medico La Raza, IMSS, Mexico City, DF, Mexico.
1151. Distinctions in the ISN/RPS 2003 Subclasses of Class IV Lupus
Nephritis. Suhail Hameed 2 , Kun Chen 2 , Surya Seshan 3 and
Michael D. Lockshin 1 , 1 Hosp for Spec Surgery, Cornell, New York,
NY, 2 Hospital for Special Surgery, Cornell, New York, NY, 3 Weill
Cornell Medical Center.
2010 Program Book 219