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B O O K - American College of Rheumatology

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Upon completion <strong>of</strong> this session, participants should be able to:<br />

• describe the clinical spectrum <strong>of</strong> inflammatory central nervous<br />

system disease in children<br />

• discuss the current diagnostic evaluation <strong>of</strong> these children<br />

• review the data on treatment <strong>of</strong> children with different<br />

presentations <strong>of</strong> central nervous system vasculitis and how<br />

this affects outcome<br />

Sidney J. Marcus Auditorium<br />

Pain, the Brain, and the Immune System: Links to<br />

Understanding Pain Management R PM<br />

Moderator: James P. Witter, MD, PhD; NIH/NIAMS; Bethesda,<br />

MD<br />

Speaker: Joyce A. DeLeo, PhD; Dartmouth Medical School;<br />

Hanover, NH<br />

Session Overview:<br />

Treatment <strong>of</strong> pain remains a major clinical challenge due to the<br />

chronic nature <strong>of</strong> many <strong>of</strong> the diseases and conditions cared<br />

for by rheumatologists. Clinicians face a dilemma, due to the<br />

recognition that pain is <strong>of</strong>ten not adequately treated, but yet at<br />

the same time current treatments are under scrutiny due to a<br />

rise in complications. Better treatment approaches are needed.<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• distinguish between acute pain and chronic pain<br />

• describe the mechanisms <strong>of</strong> chronic pain including peripheral,<br />

spinal and supraspinal sites <strong>of</strong> modulation<br />

• translate the knowledge <strong>of</strong> mechanisms <strong>of</strong> chronic pain into<br />

different therapeutic approaches with a focus on glia and the<br />

immune system<br />

8:00 am<br />

2205. Safety without Borders: Upper and Lower<br />

Gastrointestinal Safety <strong>of</strong> Celecoxib in a Pooled Analysis <strong>of</strong><br />

52 Prospective, Randomised, Double-Blinded, Parallel-Group<br />

Clinical Trials.<br />

Gurkirpal Singh 3 , George Triadafilopoulos 3 , Naurang Agrawal 1 ,<br />

Ge<strong>of</strong>f Makinson 2 , Chunming Li 2 and Ha Nguyen 2 , 1 KUMC, 2 Pfizer,<br />

3<br />

Stanford University<br />

8:15 am<br />

2206. Dose Matters: The Risk <strong>of</strong> Complicated Gastroduodenal<br />

Ulcers with Naproxen Is Dose-Dependent.<br />

Gurkirpal Singh 3 , Ajitha Mannalithara, Amrita Sehgal 4 , Alka<br />

Mithal 2 , Mark Sostek 1 and George Triadafilopoulos 3 , 1 Astra<br />

Zeneca, 2 ICORE, 3 Stanford University, 4 University <strong>of</strong> California<br />

Berkeley<br />

8:30 am<br />

2207. Disappointing Responsiveness <strong>of</strong> the SF-6D to<br />

Improvement in Patients Receiving a First TNF-Blocker: Results<br />

<strong>of</strong> the DREAM Registry.<br />

Laurien Buitinga 3 , Louise M. A. Braakman-Jansen 4 , Erik Taal 4 ,<br />

Wietske Kievit 1 , Henk Visser 2 , Piet L. C. M . Van Riel 1 and Mart A.<br />

F. J. van de Laar 5 , 1 Radboud University Nijmegen Medical Centre,<br />

2<br />

Rijnstate Hospital, Arnhem, 3 University <strong>of</strong> Twente, Enschede,<br />

Overijssel, The Netherlands, 4 University <strong>of</strong> Twente, Enschede,<br />

The Netherlands, 5 University <strong>of</strong> Twente; Medical Spectrum<br />

Twente, Enschede<br />

ARHP Concurrent Sessions<br />

7:45 - 8:45 am<br />

thursday<br />

ARHP Concurrent Abstract Session<br />

7:45 - 8:45 am<br />

B311<br />

Rheumatic Medications: More or Less?<br />

Moderator: Donald R. Miller, PharmD; North Dakota State<br />

University; Fargo, ND<br />

7:45 am<br />

2204. Periodontal Disease Hampers Anti-TNF Treatment<br />

Response in Rheumatoid Arthritis.<br />

Cynthia Savioli 1 , Gisele Maria Campos Fabri 2 , Ana Luisa Calich 5 ,<br />

Ana Cristina Medeiros Ribeiro 5 , Julio Cesar Moraes 5 , Carla<br />

Gonçalves Saad 5 , Jozélio Freire Carvalho 5 , Clovis Almeida Silva 4 ,<br />

Eloísa Bonfá 5 and José Tadeu Tesseroli Siqueira 3 , 1 Dentistry and<br />

<strong>Rheumatology</strong> Division (CEDMAC), Faculdade de Medicina da<br />

Universidade de São Paulo, Osasco, São Paulo, Brazil, 2 Dentistry<br />

and <strong>Rheumatology</strong> Division (CEDMAC), Faculdade de Medicina<br />

da Universidade de São Paulo, 3 Dentistry Division, Faculdade<br />

de Medicina da Universidade de São Paulo, 4 Paediatric<br />

<strong>Rheumatology</strong> Unit, <strong>Rheumatology</strong> Division (CEDMAC),<br />

Faculdade de Medicina da Universidade de São Paulo,<br />

5<br />

<strong>Rheumatology</strong> Division (CEDMAC), Faculdade de Medicina da<br />

Universidade de São Paulo<br />

B308<br />

How to Understand and Apply the Results <strong>of</strong> a Journal<br />

Article: What You Really Need to Know About<br />

Statistics c/r<br />

Moderator: Robert R. McLean, DSc, MPH; Hebrew Senior Life;<br />

Boston, MA<br />

Speaker: Nancy A. Baker, ScD OTR/L; University <strong>of</strong> Pittsburgh;<br />

Pittsburgh, PA<br />

Session Overview:<br />

As health care moves towards making evidence-based practice a<br />

standard <strong>of</strong> care, it is increasingly necessary for practitioners to<br />

have the tools for integrating evidence into practice. To achieve<br />

evidence-based practice health care practitioners must be able<br />

to read and understand the results <strong>of</strong> a research study so they<br />

can apply the results to clinical practice. Unfortunately, many<br />

health care practitioners are unable to interpret the statistics<br />

used in a typical journal article. Interpreting and communicating<br />

the evidence to patients, clinical associates and third party<br />

payers is difficult without the ability to understand statistics. This<br />

presentation will assist practitioner to link evidence to practice<br />

by providing practitioners with a concrete explanation <strong>of</strong> basic<br />

statistics and their interpretation. From this knowledge <strong>of</strong><br />

statistics, the results <strong>of</strong> a research article will be interpreted and<br />

then applied to a case study drawn from clinical practice.<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• describe the basic types <strong>of</strong> statistics and how to interpret<br />

them<br />

134<br />

2010 Program Book

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