B O O K - American College of Rheumatology

ACR Poster Session A
341. The Incidence of Herpes Zoster in Seniors with Rheumatoid
Arthritis. Jessica Widdifield 7 , Sasha R. Bernatsky 2 , J. Michael
Paterson 1 , Nadia Gunraj 1 , Janet E. Pope 5 , J. Carter Thorne 4 ,
Alfred A. Cividino 3 and Claire Bombardier 6 , 1 Institute for Clinical
Evaluative Science, 2 McGill UHC/RVH, Montreal, QC, Canada,
3
McMaster University, Hamilton, ON, Canada, 4 Southlake
Regional Health Care, Newmarket, ON, Canada, 5 St Joseph
Health Care London, London, ON, Canada, 6 University of
Toronto, Toronto, ON, Canada, 7 University of Toronto.
342. The Influence of Systemic Glucocorticoid Therapy upon the
Risk of Non-Serious Infection in Patients with Rheumatoid
Arthritis. William G. Dixon 3 , Abbas Kezouh 2 , Sasha R. Bernatsky 1
and Samy Suissa 2 , 1 McGill UHC/RVH, Montreal, QC, Canada,
2
McGill University, 3 The University of Manchester, Manchester,
United Kingdom.
343. Three Months of Therapy with DMARDs Is an Inadequate
Period of Time To Alter the Treatment in Patients with Early
Rheumatoid Arthritis When Treating to a Target of Low Disease
State or Remission. Results from Canadian Early ArThritis
CoHort (CATCH). Pooneh Akhavan 4 , Vivian P. Bykerk 5 , Ye Sun 6 ,
J. Hochman 12 , Janet E. Pope 9 , Carol A. Hitchon 1 , Gilles Boire 10 ,
Boulos Haraoui 2 , Diane S. Ferland 7 , J. Carter Thorne 8 , Deborah
A. Weber 5 , Ed C. Keystone 11 and CATCH Investogators 3 , 1 Arthritis
Center, University of Manitoba, Winnipeg, MB, Canada, 2 Institut
de Rhumatologie, Montreal, QC, Canada, 3 M, Canada, 4 Mount
Sinai Hospital, University of Toronto, Toronto, ON, Canada, 5 Mt
Sinai Hospital, Toronto, ON, Canada, 6 Mt Sinai Hospital, Toronto,
ON, Canada, 7 Rheumatology, Hopital Maisonneuve, Rosement,
University of Montreal, LaSalle, QC, Canada, 8 Southlake Regional
Health Care, Newmarket, ON, Canada, 9 St Joseph Health Care
London, London, ON, Canada, 10 Universite de Sherbrooke,
Sherbrooke, QC, Canada, 11 University of Toronto, Toronto, ON,
Canada, 12 University of Toronto, Toronto, ON.
344. Treating to Target with TNFi in Active Established Rheumatoid
Arthritis Results in Longer Drug Survival Than Routine Care
with TNFi: Results from the Optimization of Humira RCT. Janet
E. Pope 4 , J. Carter Thorne 3 , Boulos Haraoui 2 and John Sampalis 1 ,
1
Montreal, ON, Canada, 2 Institut de Rhumatologie, Montreal,
QC, Canada, 3 Southlake Regional Health Care, Newmarket, ON,
Canada, 4 St. Joseph’s Health Care, London, ON, Canada.
345. Tumor Necrosis Factor-α Inhibitor Use Does Not Affect Lipid
Profiles in Patients with Rheumatoid Arthritis. Stephanie J.
Morris 1 , Jana L. Antohe 1 , Jennifer Sartorius 2 , H. Les Kirchner 2 ,
Sorina Dancea 1 , Mary Chester Wasko 3 and Androniki Bili 1 ,
1
Geisinger Health System, Danville, PA, 2 Geisinger Health
System, 3 Univ of Pittsburgh, Pittsburgh, PA.
346. Urinary Tract Infections in Rheumatoid Arthritis. Colin C.
Edgerton 1 , Kaleb D. Michaud 3 and Frederick Wolfe 2 , 1 Eisenhower
Army Medical Center, Evans, GA, 2 Natilonal Data Bank for
Rheumatic Disease, Wichita, KS, 3 Univ of Nebraska Med Ctr,
Omaha, NE.
347. Women with RA Achieve Remission Less Frequently Than Men,
Using the CORRONA Database among 6668 Patients. Daniel E.
Furst 5 , Veena Ranganath 4 , Joel M. Kremer 1 , James Louie 4 , Dinesh
Khanna 4 , Lawrence Rasouliyan 2 and Jeffrey D. Greenberg 3 ,
1
Albany Medical College, 2 ICON, 3 NYU, 4 UCLA, 5 University of
California Los Angeles Medical School, Los Angeles, CA.
Rheumatoid Arthritis - Human Etiology and Pathogenesis I
348. A Novel Splicing Regulatory Mechanism in Generating a
Truncated Human Death Receptor 3 (DR3) Gene Product That
Contributes to the Pathogenesis of Rheumatoid Arthritis.
Masaru Mizuhara 2 , Akira Hashiramoto 3 , Kohsuke Yoshida 1 and
Shunichi Shiozawa 4 , 1 Department of Biophysics, Kobe University
Graduate School of Health Science, Kobe, Hyogo, Japan,
2
Department of Biophysics, Kobe University Graduate School of
Health Science, Kobe, Japan, 3 Department of Biophysics, Kobe
University Graduate School of Health Science/Department of
Medicine, Kobe University Graduate School of Medicine/The
Center for Rheumatic Diseases, Kobe University Hospital, Kobe,
Hyogo, Japan, 4 Department of Biophysics, Kobe University
Graduate School of Health Science/Department of Medicine,
Kobe University Graduate School of Medicine/The Center for
Rheumatic Diseases, Kobe University Hospital, Kobe, Japan.
349. BAFF Expression on the Surface of RA Synovial Fibroblasts
(RASFib) Facilitates B Cell Responses to IL-15. Yolanda
Garcia-Carmona, Marta Benito-Miguel, Alejandro Balsa, Emilio
Martin-Mola and Maria Eugenia Miranda-Carus, Hospital La Paz,
Madrid, Spain, Hospital La Paz, Madrid, Spain, Hospital La Paz,
Madrid.
350. Characterization of Fibrinogen-Specific CD4 T Cells Using
Peptide-MHC Tetramers. Laura F. Su 1 and Mark M. Davis 2 ,
1
Stanford, Mountain View, CA, 2 Stanford.
351. Defective ERK Signaling in Hematopoietic Progenitor Cells in
Rheumatoid Arthritis. Ines Colmegna 2 , Sergei Pryschep 1 , Hisashi
Oishi 3 , Jorg J. Goronzy 3 and Cornelia M. Weyand 3 , 1 Georgia
Institute of Technology, 2 McGill University, Montreal, QC,
Canada, 3 Stanford University.
352. Human STEAP4 (Six-Transmembrane Epithelial Antigen
of Prostate 4) Regulates Inflammatory Cytokines and the
Proliferation of Fibroblast-Like Synoviocyte in Patients
with RA. Yoko Tanaka, Isao Matsumoto, Naoto Umeda, Kayo
Yamamoto, Yuki Tanaka, Asuka Inoue and Takayuki Sumida,
University of Tsukuba.
353. IL-15 Promotes Osteoclastogenesis Via Phospholipase D
Signaling Pathway in Rheumatoid Arthritis. Ji-Min Kim 1 ,
Mi-Kyung Park 2 , Mi-La Cho 2 , Yong-Geun Jung 1 , Su-Jin Moon 1 ,
Seung-Ki Kwok 1 , Ji-Hyeon Ju 1 , Kyung-Su Park 1 , Ho-Youn Kim 1
and Sung-Hwan Park 1 , 1 Division of Rheumatology, Department
of Internal Medicine, Seoul St. Mary’s Hospital, The Catholic
University of Korea, Seoul, Korea, Republic of, 2 Rheumatism
Research Center, Catholic Research Institute of Medical Science,
The Catholic University of Korea, Seoul, Korea, Republic of.
354. IL-17A and IL-17F Contribute to the Progression of Rheumatoid
Arthritis by Inducing a CXCR4-Dependent Invasive Phenotype
in Synoviocytes. Arnaud Hot 2 , Saloua Zrioual 1 , Vanina Lenief 1
and Pierre Miossec 1 , 1 Hospital Edouard Herriot, Lyon, Lyon,
France, 2 Immunogenomics and Inflammation Research Unit
and Department of Immunology and Rheumatology, Hospital
Edouard Herriot, Lyon, France.
355. In Rheumatoid Arthritis, Naïve B Cells Prevail in the Peripheral
Blood, Whereas Memory B Cells Accumulate in the Joint
Compartment, Express ZAP-70 and Characterize the Aggregate
Pattern. Alessandro Michelutti 2 , Elisa Gremese 2 , Barbara
Tolusso 2 , Francesca Morassi 1 , Rosalia Privitera 2 , Silvia Canestri 2 ,
Giusy Peluso 2 , Silvia L. Bosello 2 and Gianfranco Ferraccioli 2 ,
1
Division of Histopathology, Catholic University of Sacred Heart,
Rome, Italy, 2 Division of Rheumatology, Catholic University of
Sacred Heart, Rome, Italy.
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2010 Program Book