B O O K - American College of Rheumatology

ACR/ARHP Poster Session B
886. Screening for Hereditary Hemochromatosis in the
Rheumatology Practice. Gunther Neeck 1 , Helge Wernitzsch 2 ,
Andreas Klüter 2 , Martin Schulz 2 and Helmut Dotzlaw 2 , 1 Center
for Rheumatology at Hospital Bad Doberan, Hohenfelde,
Germany, 2 Center for Rheumatology at Hospital Bad Doberan,
Germany.
887. Synovial Extracellular Matrix Remodeling in Experimental
Model of Diabetes. Sandra Aparecida Atayde 1 , Priscila Cristina
Andrade 2 , Sérgio Catanozi 2 , Edna Regina Nakandakare 2 , Marisa
Passarelli 2 , Ana Paula Pereira Velosa 2 , Vera Luiza Capelozzi 2 ,
Edwin Roger Parra 2 , Natalino Hajime Yoshinari 2 and Walcy
Rosolia Teodoro 2 , 1 University of São Paulo, São Paulo, Brazil,
2
University of São Paulo.
888. The GOSPEL 1000 Study. Features of the Metabolic Syndrome
in 1003 French Patients with Gout. Frédéric P. Lioté 7 , Hang-
Korng Ea 2 , Pascal Guggenbuhl 1 , Alain Saraux 6 , Charles Lambert,
Sabine Lanz 4 , Pierre Chiarelli 3 and Sylvie Lancrenon 5 , 1 Rennes,
France, 2 Paris, France, 3 Courbevoie, France, 4 Chatou, France,
5
Bourg-la-Reine, France, 6 CHU de la Cavale Blanche, Brest Cedex,
France, 7 Hopital Lariboisiere, Paris, France.
889. Ultrasound Detects More Erosions in Gout Than Conventional
Radiography. Ralf G. Thiele 2 and Naomi Schlesinger 1 , 1 UMDNJ/
RWJMS, 2 University of Rochester, Rochester, NY.
Miscellaneous Rheumatic and Inflammatory Diseases I
890. A Comprehensive Tuberculosis Screening Program in Patients
with Inflammatory Arthritis Treated with Golimumab, a
Human Anti-TNF Antibody, in Phase 3 Clinical Trials. Elizabeth
C. Hsia 4 , John J. Cush 1 , Eric L. Matteson 5 , Anna Beutler 2 ,
Mittie K. Doyle 4 , Benjamin L. Hsu 3 and Mahboob U. Rahman 4 ,
1
Baylor Research Institute, Dallas, TX, 2 Centocor Research and
Development, Inc., Collegeville, PA, 3 Centocor Research and
Development, Inc./Univ. of Pennsylvania School of Medicine,
Wynnewood, PA, 4 Centocor Research and Development, Inc./
Univ. of Pennsylvania School of Medicine, Malvern, PA, 5 Mayo
Clinic, Rochester, MN.
891. Anakinra in Adult Onset Stills Disease (AOSD). Clinically
Beneficial Results in an Open, Randomized, Multicenter Study.
Dan C. Nordström 3 , Ann Knight 11 , Reijo Luukkainen 8 , Ronald
V. Vollenhoven 5 , Vappu Rantalaiho 9 , Anna Karjalainen 7 , Johan
Brun 2 , Anne Proven 6 , Lotta Ljung 10 , Hannu Kautiainen 1 and
Tom Pettersson 4 , 1 Central Finland Central Hospital, Finland,
2
Haukeland University Hospital, Norway, 3 Helsinki Univerity
Central Hospital, Finland, 4 Helsinki University Central Hospital,
Finland, 5 Karolinska Hospital, Sweden, 6 Martina Hansens
Hospital, Norway, 7 Oulu University Hospital, Finland, 8 Rauma
Hospital, Finland, 9 Tampere University Hospital, Finland, 10 Umeå
University Hospital, Sweden, 11 Uppsala University Hospital,
Sweden.
892. Anti-Double Stranded DNA and Other Autoantibodies Are
Common in Alaska Native Autoimmune Hepatitis Patients.
Elizabeth D. Ferucci 1 , Kathy J. Hurlburt 1 , Stephen Livingston 1 ,
Julia Plotnik 1 , James Gove 1 , Brian J. McMahon 1 and Judith A.
James 2 , 1 Alaska Native Tribal Health Consortium, 2 Oklahoma
Medical Research Foundation, Oklahoma City, OK.
893. Anti-U1C Autoantibody Specifically Interferes with the U1RNP-
Mediated Splicing of Angiopoietin-1 (Ang1) Gene and Induces
Functionally Defective Ang-1/ins Variant in the Patients with
MCTD. Yuka Kosugi 1 , Koichiro Komai 1 , Shogo Funaki 1 , Aya
Mashida 1 , Kazuko Shiozawa 3 , Akira Hashiramoto 2 and Shunichi
Shiozawa 2 , 1 Dep. of Biophysics, Graduate School of Health
Sciences, Kobe Univ., Kobe, Japan, 2 Dep. of Biophysics, Graduate
School of Health Sciences, Kobe Univ./Dep. of Medicine,
Graduate School of Medicine, Kobe Univ./The Center for
Rheumatic Diseases, Kobe Univ., Hosp., Kobe, Japan, 3 Rheumatic
Diseases Center, Konan Kakogawa Hosp., Kakogawa, Japan.
894. Autoimmune Phenomena in Muckle-Wells Syndrome (MWS).
Katharina Gramlich 1 , Reinhild Klein 4 , Sandra Hansmann 3 ,
Susanne M. Benseler 5 and Jasmin B. Kuemmerle-Deschner 2 ,
1
Division of Pediatric Rheumatology, Department of Pediatrics,
University Hospital Tübingen, Tuebingen, Germany, 2 Division of
Pediatric Rheumatology, Department of Pediatrics, University
Hospital Tübingen, Tuebingen, Germany, 3 Division of Pediatric
Rheumatology, Department of Pediatrics, University Hospital
Tübingen, Germany, 4 Division of Rheumatology, Department of
Internal Medicine, University Hospital Tübingen, 5 The Hospital
for Sick Children, Toronto, ON, Canada.
895. Canakinumab (ILARIS®) Provides Rapid Response and
Sustained Remission in Cryopyrin-Associated Periodic
Syndrome (CAPS) Patients across All Severity Phenotypes.
H. J. Lachmann 12 , J. B. Kuemmerle-Deschner 6 , E. Hachulla 3 , R.
Cartwright 1 , I. Kone-Paut 4 , J. Hoyer 2 , P. Quartier 11 , J. Smith 14 ,
M. Gattorno 5 , K. Leslie 10 , J. Braun 9 , A. Widmer 7 , N. Patel 8 , R.
Preiss 8 and P. N. Hawkins 13 , 1 Allergy Center at Brookstone,
Columbus, GA, 2 Department of Internal Medicine and
Nephrology, Universitaetsklinikum Giessen und Marburg
GmbH, Marburg, Germany, 3 Hôpital Claude Huriez CHRU, Lille
Cedex, France, 4 Hôpital Kremlin Bicetre, CEREMAI, Le Kremlin
Bicetre, France, 5 Istituto Giannina Gaslini, Genova, Italy,
6
Klinik fuer Kinder-und Jugendmedizin, Universitaetsklinikum,
Tuebingen, Germany, 7 Novartis Pharma AG, Basel, Switzerland,
8
Novartis Pharmaceuticals Corporation, East Hanover, NJ,
9
Rheumazentrum Ruhrgebiet, Herne, Germany, 10 UCSF School
of Medicine, San Francisco, CA, 11 Unit’e d’Immunologie,
Hematologie et Rhumatologie Pediatrique, Hopital Necker-
Enfants Malades, Paris, France, 12 University College London
Medical School, London, United Kingdom, 13 University College
London Medical School, London, United Kingdom, 14 University
of Wisconsin Hospital and Clinics, Madison, WI.
896. Celecoxib Analogue Lacking COX-2-Inhibitory Activity Inhibits
Arthritis by Supressing IL-23 and Inflammatory Cytokines.
Asako Chiba 2 , Ryohsuke Tajima 2 , Miho Mizuno 2 , Chiharu Tomi 2 ,
Iraide Alloza 3 , Takashi Yamamura 2 , Koen Vandenbroeck 3 and
Sachiko Miyake 1 , 1 Department of Immunology, National Institute
of Neuroscience, NCNP, Kodaira Tokyo, Japan, 2 Department
of Immunology, National Institute of Neuroscience, NCNP,
3
Neurogenomiks Laboratory, Ikerbasque and Universidad Del
País Vasco (UPV/EHU), Parque Tecnológico de Bizkaia.
897. Comprehensive Analyses of MEFV, TNFRSF1A, MVK, and
CIAS1 Mutations in 63 Patients with Clinically Periodic Fever
Syndrome in Japan. Sayuri Kataoka 2 , Manabu Kawamoto 1 ,
Yasushi Kawaguchi 3 , Takahisa Gono 1 , Masanori Hanaoka 1 , Hisae
Ichida 1 , Yasuhiro Katsumata 1 , Yuko Okamoto 4 , Yuko Ota 2 , Ikuko
Masuda 1 and Hisashi Yamanaka 1 , 1 Tokyo Women’s Medical
University, 2 Tokyo Women’s Medical University, Japan, 3 Tokyo
Women’s Medical University, 4 Tokyo Womens Med Univ.
2010 Program Book 201