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B O O K - American College of Rheumatology

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5:45 PM<br />

699. Defining Latent and/or Disseminated Active Tuberculous<br />

Infection with TST, Quantiferon Gold and Multisite Cultures in<br />

TNFi Exposed Individuals.<br />

Dilrukshie Cooray 2 , James S. Louie 4 , Rosalinda C. Moran 1 and<br />

George A. Karpouzas 3 , 1 Harbor- UCLA Medical Center, Carson,<br />

CA, 2 Harbor-UCLA Medical Center, Torrance, CA, 3 Harbor-UCLA<br />

Medical Center, Long Beach, CA, 4 University <strong>of</strong> California Los<br />

Angeles, Los Angeles, CA<br />

A404<br />

Miscellaneous Rheumatic and Inflammatory Diseases<br />

Moderators: W. Winn Chatham, MD; University <strong>of</strong> Alabama-<br />

Birmingham; Birmingham, AL<br />

Kristine M. Lohr, MD, MS; Kentucky Clinic; Lexington, KY<br />

4:30 PM<br />

700. Progressive Multifocal Leukoencephalopathy Associated<br />

with Biologic and Synthetic DMARD Therapy in Rheumatic<br />

Diseases: An Analysis <strong>of</strong> the FDA Adverse Event Reporting<br />

System Database.<br />

Eamonn S. Molloy 2 and Leonard H. Calabrese 1 , 1 Cleveland Clinic<br />

Foundation, Cleveland, OH, 2 St Vincent’s University Hospital,<br />

Dublin, Ireland<br />

4:45 PM<br />

701. Tocilizumab in Refractory Adult Still’s Disease: A Cohort<br />

Study.<br />

Xavier Puéchal, Michel de Bandt, Jean-Marie Berthelot, Maxime<br />

Breban, Jean-Jacques Dubost, Olivier Fain, Jean-Emmanuel Kahn,<br />

Laurence Lequen, Maïté Longy-Boursier, Aleth Perdriger, Thierry<br />

Schaeverbeke, Eric Toussirot, Jean Sibilia and The CRI, Center<br />

for Rare Systemic and Auto-immune Diseases, Department <strong>of</strong><br />

<strong>Rheumatology</strong>, Le Mans, France<br />

5:00 PM<br />

702. Clinical Implications <strong>of</strong> the NMO-IgG Antibody and<br />

Overlapping Neuromyelitis Optica Spectrum Disorder in<br />

Patients with Connective Tissue Disease and Myelitis.<br />

Jason R. Kolfenbach 1 , Brian J. Horner 3 and Sterling G. West 2 ,<br />

1<br />

Division <strong>of</strong> <strong>Rheumatology</strong>, University <strong>of</strong> Colorado at Denver,<br />

Aurora, CO, 2 University <strong>of</strong> Colorado at Denver, Aurora, CO,<br />

3<br />

University <strong>of</strong> Colorado Denver School <strong>of</strong> Medicine<br />

5:15 PM<br />

703. Diagnostic Significance <strong>of</strong> Serum Interleukin-18 Level in<br />

Adult-Onset Still’s Disease.<br />

Junko Maruyama 3 , Shigeko Inokuma 1 and Noboru Hagino 2 ,<br />

1<br />

Japanese Red Cross Medical Center, 2 The University <strong>of</strong> Tokyo<br />

Hospital, 3 Tokyo Metropolitan Komagome Hospital, Tokyo, Japan<br />

5:30 PM<br />

704. Extrapulmonary Course <strong>of</strong> Connective Tissue Disease and<br />

Survival after Lung Transplant.<br />

Troy K. Takagishi, Iffat Ahmed and Rodney Tehrani, Loyola<br />

University Medical Center<br />

5:45 PM<br />

705. Idiopathic Retroperitoneal Fibrosis: Treatment-Related<br />

Outcomes and Predictors <strong>of</strong> Clinical Response.<br />

Tanaz A. Kermani 1 , Cynthia S. Crowson 2 , Sara Achenbach 2 and<br />

Harvinder S. Luthra 1 , 1 Mayo Clinic, Rochester, MN, 2 Mayo Clinic<br />

A314<br />

Osteoarthritis - Clinical Aspects: Genetics, Novel<br />

Approaches, and Therapy<br />

Moderators: Timothy E. McAlindon, MD, MPH; Tufts Medical<br />

Center; Boston, MA<br />

Tuhina Neogi, MD, PhD; Boston University School <strong>of</strong> Medicine;<br />

Boston, MA<br />

4:30 PM<br />

706. Clinical Trial <strong>of</strong> Vitamin D To Reduce Pain and Structural<br />

Progression <strong>of</strong> Knee Osteoarthritis (OA).<br />

Timothy E. McAlindon 3 , Bess Dawson-Hughes 5, Jeffrey Driban 4 ,<br />

Michael LaValley 2 , Ji Yeon Lee 4 , Grace H. Lo 1 , Melynn Nuite 4 and<br />

Lori Lyn Price 4 , 1 Baylor <strong>College</strong> <strong>of</strong> Medicine, 2 Boston University<br />

School <strong>of</strong> Public Health, 3 Tufts Medical Center, Boston, MA,<br />

4<br />

Tufts Medical Center, 5 USDA HNRC; Tufts University<br />

4:45 PM<br />

707. Interleukin-1 Receptor Antagonist (IL-1RN) Gene<br />

Variations Predict the Severity and Progression <strong>of</strong> Knee<br />

Osteoarthritis.<br />

Mukundan Attur 8 , Cheongun Oh 7 , Svetlana Krasnokutsky 6 ,<br />

Jonathan Samuels 5 , Leon Rybak 9 , Jenny Bencardino 9 , Jeffrey<br />

D. Greenberg 1 , Virginia Kraus 2 , Kenneth Kornman 4 and Steven<br />

B. Abramson 3 , 1 Millburn, NJ, 2 Duke University Medical Center,<br />

Durham, NC, 3 Hospital for Joint Dis/NYU, New York, NY,<br />

4<br />

Interleukin Genetics, 5 New York University Hospital for Joint<br />

Disease, New York, NY, 6 NYU Hospital for Joint Disease, New<br />

York, NY, 7 NYU-Hospital for Joint Diseases, 8 NYU-Hospital for<br />

Joint Diseases, New York, NY, 9 NYU-Hospital for Joint Diseases<br />

Radiology Dept.<br />

5:00 PM<br />

708. Hand Osteoarthritis (OA) a Predictor <strong>of</strong> Accelerated<br />

Progression in Knee OA?<br />

Jonathan Samuels 3 , Catherine Petchprapa 6 , Elizabeth L.<br />

Carpenter 6 , Svetlana Krasnokutsky 4 , Mukundan Attur 2 , Leon<br />

Rybak 5 , Jenny Bencardino 5 , Cheongeun Oh 6 and Steven B.<br />

Abramson 1 , 1 Hospital for Joint Dis/NYU, New York, NY, 2 Hospital<br />

for Joint Dis/NYU Langone Medical Center, 3 New York University<br />

Hospital for Joint Disease, New York, NY, 4 NYU Hospital for Joint<br />

Disease, New York, NY, 5 NYU Hospital for Joint Diseases, 6 NYU<br />

Langone Medical Center<br />

5:15 PM<br />

709. Bone Marrow Lesions (BMLs) Are Strongly Associated with<br />

Increased Bone Volume Fraction; “Virtual Bone Biopsy” Using<br />

MRI.<br />

Anna M. Tassinari 3 , Grace H. Lo 1 , Jeffrey Driban 3 , Lori Lyn Price 3 ,<br />

Erika Schneider 2 and Timothy E. McAlindon 3 , 1 Baylor <strong>College</strong> <strong>of</strong><br />

Medicine, Houston, TX, 2 The Cleveland Clinic, Cleveland, OH,<br />

3<br />

Tufts Medical Center, Boston, MA<br />

5:30 PM<br />

710. REGN475/SAR164877, a Nerve Growth Factor Inhibitor,<br />

in Osteoarthritis Patients with Moderate to Severe Knee Pain:<br />

Results <strong>of</strong> a Phase 2, Randomized, Double-Blind, Placebo-<br />

Controlled Study.<br />

Paul Tiseo 4 , Alan J. Kivitz 1 , John E. Ervin 2 , Scott J. Mellis 3 ,<br />

Haobo Ren 4 , Damir Skific 4 , Richard Wu 4 and Peter Powchik 4 ,<br />

1<br />

Altoona Arthritis & Osteo Ctr, Duncansville, PA, 2 Center<br />

for Pharmaceutical Res, Kansas City, MO, 3 Regeneron<br />

Pharmaceuticals, Inc., Tarrytown, NY, 4 Regeneron<br />

Pharmaceuticals, Inc.<br />

2010 Program Book 49<br />

monday

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