B O O K - American College of Rheumatology
B O O K - American College of Rheumatology
B O O K - American College of Rheumatology
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Session Overview:<br />
We are witnessing a rapid increase in the use <strong>of</strong> web-based tools<br />
by health care practitioners and educators to facilitate clinical<br />
activities and instructional sessions. The ease <strong>of</strong> use and speed<br />
<strong>of</strong> deployment makes Twitter, blogs, and wikis effective forums<br />
for communication. However, determining the most appropriate<br />
format for the specific needs <strong>of</strong> your practice, lecture, or class<br />
can be overwhelming. This interactive session will review key<br />
features for evaluating technological formats, demonstrate the<br />
use <strong>of</strong> Twitter, blogs, and wikis, and discuss how practitioners<br />
and educators have specifically used these technologies.<br />
Upon completion <strong>of</strong> this session, participants should be able to:<br />
• identify features <strong>of</strong> web-based tools such as content<br />
integration and discussion forums for evaluating technological<br />
formats<br />
• describe how to create Twitter accounts, blogs, and wikis<br />
• discuss how Twitter, blogs, and wikis can enhance clinical<br />
practice and instructional sessions<br />
ACR Basic Science Symposia<br />
4:30 - 6:00 PM<br />
B402<br />
A Critical Role for Lipid Metabolism in the Interplay<br />
between Atherosclerosis and Autoimmune Disorders<br />
R<br />
Moderators: Radjesh Bisoendial, MD, PhD; Academic Medical<br />
Center University <strong>of</strong> Amsterdam; Amsterdam, Netherlands<br />
Zoltan Szekanecz, MD, PhD, DSC; University <strong>of</strong> Debrecen Medical<br />
Center; Debrecen, Hungary<br />
4:30 PM<br />
High-Density Lipoprotein Regulates Cellular Immune Responses<br />
via Adenosine Triphosphate-binding Cassette<br />
Alan Tall, MD; Columbia University; New York, NY<br />
5:00 PM<br />
The Dual Function <strong>of</strong> High Density Lipoproteins to Suppress<br />
Inflammatory Activity and Protect Against Heart Disease<br />
in Rheumatoid Arthrititis and Other Immune-mediated<br />
Inflammatory Diseases<br />
Kerry-Anne Rye, PhD; The Heart Research Institute; Newtown,<br />
Sydney, New South Wales, Australia<br />
5:30 PM<br />
Liver X Receptor Signaling at the Crossroads Between Immunity<br />
and Cholesterol Homeostasis<br />
Uwe JF. Tietge, MD; University Medical Center Groningen;<br />
Groningen, Netherlands<br />
Session Overview:<br />
Cardiovascular disease represents a major cause <strong>of</strong> increased<br />
morbidity and mortality in various immune-mediated<br />
inflammatory disorders. This symposium will provide insight into<br />
the factors involved in the increased cardiovascular risk and the<br />
underlying mechanisms.<br />
Upon completion <strong>of</strong> this session, participants should be able to:<br />
• identify the key players that integrate metabolic and<br />
inflammatory signaling in increased cardiovascular disease<br />
among individuals with immune-mediated inflammatory<br />
diseases<br />
• define the basics <strong>of</strong> the pathogenic mechanisms that drive<br />
atherosclerosis in immune-mediated inflammatory diseases<br />
B313<br />
Molecular Mechanisms <strong>of</strong> Ocular Inflammation R<br />
Moderators: James T. Rosenbaum, MD; Oregon Health & Science<br />
University; Portland, OR<br />
Holly L. Rosenzweig, PhD; Oregon Health & Science University;<br />
Portland, OR<br />
4:30 PM<br />
Is Macular Degeneration, the Leading Cause <strong>of</strong> Acquired<br />
Blindness, an Autoimmune Disease?<br />
Jayakrishna Ambati, MD; University <strong>of</strong> Kentucky; Lexington, KY<br />
5:00 PM<br />
The Role <strong>of</strong> IL-17 in Autoimmune Uveitis<br />
Rachel Caspi, PhD; National Eye Insitute; Bethesda, MD<br />
5:30 PM<br />
Are Biologic Therapies Indicated to Treat Inflammatory Eye<br />
Diseases?<br />
James T. Rosenbaum, MD; Oregon Health & Science University;<br />
Portland, OR<br />
Session Overview:<br />
The majority <strong>of</strong> rheumatologic diseases include a component <strong>of</strong><br />
ocular inflammation. A better understanding <strong>of</strong> the pathogenesis<br />
<strong>of</strong> ocular inflammation will lead to insights into inflammation in<br />
other organs involved in rheumatic diseases.<br />
Upon completion <strong>of</strong> this session, participants should be able to:<br />
• identify the relative contributions <strong>of</strong> TH1, TH2, and TH17 T cell<br />
subsets in an animal model <strong>of</strong> uveitis<br />
• describe the role <strong>of</strong> growth factors, toll receptors,<br />
chemokines, and monocytes in the pathogenesis <strong>of</strong> macular<br />
degeneration<br />
• define the role <strong>of</strong> biologic therapies in the treatment <strong>of</strong><br />
inflammatory eye diseases<br />
ACR Clinical Symposia<br />
4:30 - 6:00 PM<br />
Sidney J. Marcus Auditorium<br />
New Development in Systemic Juvenile Idiopathic<br />
Arthritis - From Bench to Effective Interventions P<br />
PS<br />
Moderators: Alexei A. Grom, MD; Children’s Hospital Medical<br />
Center; Cincinnati, OH<br />
Sampath Prahalad, MD, MSc; Emory Children’s Center; Atlanta,<br />
GA<br />
4:30 PM<br />
Introduction: Systemic Juvenile Idiopathic Arthritis as an<br />
Autoinflammatory Syndrom<br />
Sampath Prahalad, MD, MSc; Emory Children’s Center; Atlanta,<br />
GA<br />
4:40 PM<br />
IL-1 and Systemic Juvenile Idiopathic Arthritis<br />
Norman T. Ilowite, MD; Children’s Hospital Montefiore; Bronx,<br />
NY<br />
2010 Program Book 121<br />
wednesday