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B O O K - American College of Rheumatology

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Session Overview:<br />

We are witnessing a rapid increase in the use <strong>of</strong> web-based tools<br />

by health care practitioners and educators to facilitate clinical<br />

activities and instructional sessions. The ease <strong>of</strong> use and speed<br />

<strong>of</strong> deployment makes Twitter, blogs, and wikis effective forums<br />

for communication. However, determining the most appropriate<br />

format for the specific needs <strong>of</strong> your practice, lecture, or class<br />

can be overwhelming. This interactive session will review key<br />

features for evaluating technological formats, demonstrate the<br />

use <strong>of</strong> Twitter, blogs, and wikis, and discuss how practitioners<br />

and educators have specifically used these technologies.<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• identify features <strong>of</strong> web-based tools such as content<br />

integration and discussion forums for evaluating technological<br />

formats<br />

• describe how to create Twitter accounts, blogs, and wikis<br />

• discuss how Twitter, blogs, and wikis can enhance clinical<br />

practice and instructional sessions<br />

ACR Basic Science Symposia<br />

4:30 - 6:00 PM<br />

B402<br />

A Critical Role for Lipid Metabolism in the Interplay<br />

between Atherosclerosis and Autoimmune Disorders<br />

R<br />

Moderators: Radjesh Bisoendial, MD, PhD; Academic Medical<br />

Center University <strong>of</strong> Amsterdam; Amsterdam, Netherlands<br />

Zoltan Szekanecz, MD, PhD, DSC; University <strong>of</strong> Debrecen Medical<br />

Center; Debrecen, Hungary<br />

4:30 PM<br />

High-Density Lipoprotein Regulates Cellular Immune Responses<br />

via Adenosine Triphosphate-binding Cassette<br />

Alan Tall, MD; Columbia University; New York, NY<br />

5:00 PM<br />

The Dual Function <strong>of</strong> High Density Lipoproteins to Suppress<br />

Inflammatory Activity and Protect Against Heart Disease<br />

in Rheumatoid Arthrititis and Other Immune-mediated<br />

Inflammatory Diseases<br />

Kerry-Anne Rye, PhD; The Heart Research Institute; Newtown,<br />

Sydney, New South Wales, Australia<br />

5:30 PM<br />

Liver X Receptor Signaling at the Crossroads Between Immunity<br />

and Cholesterol Homeostasis<br />

Uwe JF. Tietge, MD; University Medical Center Groningen;<br />

Groningen, Netherlands<br />

Session Overview:<br />

Cardiovascular disease represents a major cause <strong>of</strong> increased<br />

morbidity and mortality in various immune-mediated<br />

inflammatory disorders. This symposium will provide insight into<br />

the factors involved in the increased cardiovascular risk and the<br />

underlying mechanisms.<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• identify the key players that integrate metabolic and<br />

inflammatory signaling in increased cardiovascular disease<br />

among individuals with immune-mediated inflammatory<br />

diseases<br />

• define the basics <strong>of</strong> the pathogenic mechanisms that drive<br />

atherosclerosis in immune-mediated inflammatory diseases<br />

B313<br />

Molecular Mechanisms <strong>of</strong> Ocular Inflammation R<br />

Moderators: James T. Rosenbaum, MD; Oregon Health & Science<br />

University; Portland, OR<br />

Holly L. Rosenzweig, PhD; Oregon Health & Science University;<br />

Portland, OR<br />

4:30 PM<br />

Is Macular Degeneration, the Leading Cause <strong>of</strong> Acquired<br />

Blindness, an Autoimmune Disease?<br />

Jayakrishna Ambati, MD; University <strong>of</strong> Kentucky; Lexington, KY<br />

5:00 PM<br />

The Role <strong>of</strong> IL-17 in Autoimmune Uveitis<br />

Rachel Caspi, PhD; National Eye Insitute; Bethesda, MD<br />

5:30 PM<br />

Are Biologic Therapies Indicated to Treat Inflammatory Eye<br />

Diseases?<br />

James T. Rosenbaum, MD; Oregon Health & Science University;<br />

Portland, OR<br />

Session Overview:<br />

The majority <strong>of</strong> rheumatologic diseases include a component <strong>of</strong><br />

ocular inflammation. A better understanding <strong>of</strong> the pathogenesis<br />

<strong>of</strong> ocular inflammation will lead to insights into inflammation in<br />

other organs involved in rheumatic diseases.<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• identify the relative contributions <strong>of</strong> TH1, TH2, and TH17 T cell<br />

subsets in an animal model <strong>of</strong> uveitis<br />

• describe the role <strong>of</strong> growth factors, toll receptors,<br />

chemokines, and monocytes in the pathogenesis <strong>of</strong> macular<br />

degeneration<br />

• define the role <strong>of</strong> biologic therapies in the treatment <strong>of</strong><br />

inflammatory eye diseases<br />

ACR Clinical Symposia<br />

4:30 - 6:00 PM<br />

Sidney J. Marcus Auditorium<br />

New Development in Systemic Juvenile Idiopathic<br />

Arthritis - From Bench to Effective Interventions P<br />

PS<br />

Moderators: Alexei A. Grom, MD; Children’s Hospital Medical<br />

Center; Cincinnati, OH<br />

Sampath Prahalad, MD, MSc; Emory Children’s Center; Atlanta,<br />

GA<br />

4:30 PM<br />

Introduction: Systemic Juvenile Idiopathic Arthritis as an<br />

Autoinflammatory Syndrom<br />

Sampath Prahalad, MD, MSc; Emory Children’s Center; Atlanta,<br />

GA<br />

4:40 PM<br />

IL-1 and Systemic Juvenile Idiopathic Arthritis<br />

Norman T. Ilowite, MD; Children’s Hospital Montefiore; Bronx,<br />

NY<br />

2010 Program Book 121<br />

wednesday

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