B O O K - American College of Rheumatology

12:00 PM
2254. The Involvement of CD36 in the Monocyte Activation by
Antiphospholipid Antibodies.
Masaru Kato 1 , Tatsuya Atsumi 2 , Kenji Oku 3 , Olga Amengual 3 ,
Yuichiro Fujieda 3 , Kotaro Otomo 3 , Tetsuya Horita 3 , Shinsuke
Yasuda 3 and Takao Koike 3 , 1 Department of Medicine II, Hokkaido
University Graduate School of Medicine, Sapporo, Hokkaido,
Japan, 2 Department of Medicine II, Hokkaido University
Graduate School of Medicine, Sapporo, Japan, 3 Department of
Medicine II, Hokkaido University Graduate School of Medicine
12:15 PM
2255. Potential Protein Targets for the Treatment
of the Antiphospholipid Syndrome with Statins and
Hydroxychloroquine.
Anastasia Lambrianides 2 , Silvia S. Pierangeli 1 , Katie Bell 3 , Wendy
Heywood 3 , David S. Latchman 3 , David A. Isenberg 3 , Anisur
Rahman 3 and Ian Giles 3 , 1 Univ of TX Medical Branch, Galveston,
TX, 2 University College London, London, United Kingdom,
3
University College London, London, UK
B313
Rheumatoid Arthritis - Clinical Aspects: Radiographic
and Other Outcomes in RA IV
Moderators: Earnest Choy, MD; Kings College Hospital; London,
United Kingdom
Piet L. Van Riel, MD, PhD; University Hospital Nijmegen;
Nijmegen, The Netherlands
12:00 PM
2260. Interleukin-6 Levels Are Associated with Elevated Ankle
Brachial Index in Rheumatoid Arthritis.
Cecilia P. Chung 4 , Jon T. Giles 3 , Moyses Szklo 5 , Wendy Post 5 ,
Michelle A. Petri 1 , Roger Blumenthal 5 , Allan C. Gelber 2 , Russell
Tracy 6 and Joan M. Bathon 4 , 1 Timonium, MD, 2 Baltimore, MD,
3
Johns Hopkins Univ, Baltimore, MD, 4 Johns Hopkins University,
Baltimore, MD, 5 Johns Hopkins University, 6 University of
Vermont
12:15 PM
2261. Diagnostic Accuracy of the 2010 ACR/EULAR Used at
Baseline after a 10 Year Follow Up in a Cohort of Patients with
Recent-Onset Arthritis.
Divi Cornec 5 , Sophie Varache 6 , Johanne Morvan 5 , Valérie
Devauchelle-pensec 5 , Jean-Marie Berthelot 7 , Sandrine Joussejoulin
5 , Catherine Le Henaff 2 , Sylvie Hoang 4 , Jean-Baptiste
Thorel 1 , Antoine Martin 3 , Gérard Chalès 8 , Pierre Youinou 5 and
Alain Saraux 5 , 1 CH Lorient, 2 CH Morlaix, 3 CH St Brieuc, 4 CH
Vannes, 5 CHU Brest, 6 CHU Brest, 7 CHU Nantes, 8 CHU Rennes
B402
Rheumatoid Arthritis Treatment - Small Molecules,
Biologics and Gene Therapy: Existing Biologics IV
Moderators: Daniel E. Furst, MD; University of California Los
Angeles Medical School; Los Angeles, CA
Veena K. Ranganath, MD; University of California Los Angeles
Medical School; Los Angeles, CA
thursday
11:00 AM
2256. Irreversible Physical Disability in Rheumatoid Arthritis
(RA) Is Determined by Cartilage Damage Rather Than Bone
Destruction.
Josef S. Smolen 2 and Daniel Aletaha 1 , 1 Medical University of
Vienna, Austria, 2 Medical University of Vienna and Hietzing
Hospital, Vienna, Austria
11:15 AM
2257. The Impact of Body Weight on the Progression of
Radiographic Joint Damage in Rheumatoid Arthritis Patients.
Axel Finckh 4 , Almut Scherer 1 , Anne Lubbeke-Wolff 3 , Hans
Schwarz 1 and Cem Gabay 2 , 1 SCQM Foundation, Switzerland,
2
Univ Hosp of Geneva, Geneva, Switzerland, 3 University of
Geneva, Switzerland, 4 University of Geneva, Geneva, Switzerland
11:30 AM
2258. Clinical Rather Than Serologic Measures of Inflammation
Determine Radiographic Progression in Rheumatoid Arthritis
(RA).
Daniel Aletaha 1 and Josef S. Smolen 2 , 1 Medical University of
Vienna, Austria, 2 Medical University of Vienna and Hietzing
Hospital, Vienna, Austria
11:45 AM
2259. Coronary Atherosclerosis in Patients with RA and Acute
Coronary Events: No Different Than in the Rest of Us?
Marie E. Holmqvist 1 , Lennart T. H. Jacobsson 3 , Lars Alfredsson 1 ,
Stefan James 4 and Johan Askling 2 , 1 Karolinska Institutet,
2
Karolinska University Hospital, 3 Malmö University Hospital,
4
Uppsala University Hospital
11:00 AM
2262. Tocilizumab (TCZ) Plus Methotrexate (MTX) in
Rheumatoid Arthritis (RA) Patients (pts) Who Increased TCZ
Dose from 4 mg/kg to 8 mg/kg: LITHE Radiographic and Safety
Data.
Roy M. Fleischmann 4 , Ricardo Blanco 2 , Geraldo Castelar-
Pinheiro 3 , Emma Vernon 5 , Christopher Mela 5 and Joel M.
Kremer 1 , 1 Albany Medical College, Albany, NY, 2 Hospital Marqués
de Valdecilla Cantabria, 3 Hospital Universitario Pedro Ernesto,
Rio de Janeiro, Brazil, 4 Metroplex Clinical Research Center,
Dallas, TX, 5 Roche, Welwyn, United Kingdom
11:15 AM
2263. Rituximab Treatment Induces the Expression of Genes
Involved in Healing Processes in the Rheumatoid Arthritis
Synovium.
Ilse Gutierrez-Roelens 4 , Christine Galant 3 , Ivan Theate 3 , Rik J.
Lories 2 , Patrick Durez 4 , Adrien Nzeusseu Toukap 4 , Benoît Van
den Eynde 1 , Frédéric A. Houssiau 4 and Bernard R. Lauwerys 4 , 1 de
Duve Institute & Ludwig Institute for Cancer Research, Brussels
Branch, 2 Department of Musculoskeletal Sciences, Division
of Rheumatology, Laboratory for Skeletal Development and
Joint Disorders, Katholieke Universiteit Leuven, 3 Department
of Pathology, Cliniques Universitaires Saint-Luc, Université
Catholique de Louvain, 4 Department of Rheumatology, Cliniques
Universitaires Saint-Luc, Université Catholique de Louvain
11:30 AM
2264. Golimumab and Methotrexate Combination Therapy
Significantly Improves Synovitis, Osteitis and Bone Erosion
Compared to Methotrexate Alone – A Magnetic Resonance
Imaging Study of Methotrexate-Naïve Rheumatoid Arthritis
Patients.
144
2010 Program Book