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B O O K - American College of Rheumatology

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tuesday<br />

6:45 PM<br />

Results from the PMR Classification Criteria Study<br />

Eric L. Matteson, MD; Mayo Clinic; Rochester, MN<br />

7:05 PM<br />

Update on Trials <strong>of</strong> Biologic Agents and Leflunomide in PMR<br />

and GCA<br />

Bhaskar Dasgupta, MD; Southend University Hospital; Essex,<br />

United Kingdom<br />

7:25 PM<br />

A Study <strong>of</strong> Educational Needs <strong>of</strong> Patients with PMR and GCA<br />

Richard Watts, DM; Ipswich Hospital; Ipswich, United Kingdom<br />

7:45 PM<br />

Update on Study <strong>of</strong> Temporal Artery Ultrasound Versus Biopsy<br />

in GCA<br />

Raashid Luqmani, DM; Nuffield Department <strong>of</strong> Orthopaedics,<br />

<strong>Rheumatology</strong> and Musculoskeletal Sciences; Oxford, United<br />

Kingdom<br />

Session Overview:<br />

The study group will be the forum for presenting results from<br />

the Prospective PMR Classification Criteria Study. It will also<br />

feature updates on therapeutic trials in PMR and GCA with<br />

leflunomide and biologic agents. A study <strong>of</strong> educational needs <strong>of</strong><br />

patients with PMR and GCA will be presented. Attendees will be<br />

updated on study <strong>of</strong> temporal artery ultrasound versus biopsy<br />

in GCA.<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• describe results from the PMR classification criteria study<br />

• update on trials <strong>of</strong> leflunomide and biologic agents in PMR<br />

and GCA<br />

• explain a study <strong>of</strong> educational needs <strong>of</strong> patients with PMR and<br />

GCA<br />

• explain the study <strong>of</strong> temporal artery ultrasound versus biopsy<br />

in GCA<br />

B314<br />

Psoriatic Arthritis and Periarticular Imaging: Focus on<br />

Enthesitis, Dactylitis, and Nail Disease<br />

Moderators: Elaine Husni, MD, MPH; Cleveland Clinic<br />

Foundation; Cleveland, OH<br />

Philip Helliwell, MD, PhD; University <strong>of</strong> Leeds; Leeds, United<br />

Kingdom<br />

6:45 PM<br />

The Role <strong>of</strong> Enthesitis in the Pathogenesis <strong>of</strong> Psoriatic Arthritis<br />

Dennis McGonagle, PhD; University <strong>of</strong> Leeds; Leeds, United<br />

Kingdom<br />

7:10 PM<br />

Clinical Assessment <strong>of</strong> Enthesitis: How Should This Be Done?<br />

Philip Helliwell, MD, PhD; University <strong>of</strong> Leeds; Leeds, United<br />

Kingdom<br />

7:35 PM<br />

Use <strong>of</strong> Ultrasound and Magnetic Resonance Imaging: Focus on<br />

Periarticular Disease in Patients with Psoriatic Arthritis<br />

Ralf G. Thiele, MD; University <strong>of</strong> Rochester; Rochester, NY<br />

Session Overview:<br />

Psoriatic arthritis is a unique inflammatory arthritis that<br />

encompasses both skin and joint involvement with common<br />

periarticular manifestations such as enthesitis and dactylitis. In<br />

fact, the initial insult may be enthesitis rather than the synovium<br />

and current area <strong>of</strong> research interest is in the early evaluation<br />

and detection <strong>of</strong> these clinical parameters. Therapeutic decisions<br />

may be influenced by the presence <strong>of</strong> active enthesis/dactylitis<br />

and current techniques <strong>of</strong> clinical examination and standard<br />

radiographs may underestimate the overall inflammatory<br />

burden. With the advances <strong>of</strong> imaging modalities, we will<br />

explore the utility <strong>of</strong> ultrasound and MRI for psoriatic diseases.<br />

We hope to bring together multidisciplinary disciplines in<br />

musculoskeletal radiologist and rheumatologist to help advance<br />

the field <strong>of</strong> psoriatic arthritis.<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• describe the overview <strong>of</strong> advances in imaging such as<br />

ultrasound in the utility <strong>of</strong> periarticular tissues in psoriatic<br />

arthritis<br />

• explore the relationship <strong>of</strong> immunohistology and imaging <strong>of</strong><br />

skin and joints for psoriatic diseases<br />

• identify the pathobiology and immuno-pathology underlying<br />

enthesitis in psoriatic disorders<br />

• appreciate the several clinical scoring methods for enthesitis,<br />

their reliability, sensitivity and specificity<br />

B309<br />

Sjögren’s Syndrome<br />

Moderators: Gabor G. Illei, MD; NIDCR/NIH; Bethesda, MD<br />

Nikolay P. Nikolov, MD; FDA/CDER/OND; Silver Spring, MD<br />

6:45 PM<br />

Animal Models in Sjögren’s Syndrome: Are They Any Good?<br />

Umesh Desmukh, PhD; University <strong>of</strong> Virginia; Charlottesville, VA<br />

7:10 pm<br />

From Bench to Bedside: Biological Markers <strong>of</strong> Disease Activity<br />

and Prognosis in Primary Sjögren’s Syndrome<br />

Jacques-Eric Gottenberg, MD, PhD; University <strong>of</strong> Strasbourg,<br />

France<br />

7:35 pm<br />

Autonomic Dysfunction: An Often Overlooked Feature <strong>of</strong><br />

Primary Sjogren’s Syndrome<br />

Thomas Mandl, MD, PhD: Malmo University Hospital; Malmo,<br />

Sweden<br />

Session Overview:<br />

The study group will address three topics ranging from animal<br />

models to clinical aspects <strong>of</strong> Sjögren’s syndrome providing inside<br />

in both the pathogenesis and clinical management <strong>of</strong> Sjögren’s<br />

syndrome. Speakers will discuss the role <strong>of</strong> B lymphocyte<br />

subsets and inflammatory mediators in the pathogenesis <strong>of</strong><br />

Sjögren’s and their potential as biomarkers, the advantages<br />

and limitations <strong>of</strong> various animal models and their relevance<br />

to human disease and the pathogenesis and treatment<br />

<strong>of</strong> autonomic dysfunction, one <strong>of</strong> the most challenging<br />

manifestation <strong>of</strong> Sjögren’s Syndrome. All three speakers will<br />

cover the basic aspects and the clinical implications <strong>of</strong> their<br />

topics.<br />

92<br />

2010 Program Book

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