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B O O K - American College of Rheumatology

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tuesday<br />

These collated data will provide the most comprehensive map<br />

<strong>of</strong> the presence and relative importance <strong>of</strong> MSK disease ever<br />

developed. There is a great need to allow international groups<br />

access to the findings and support individuals and organizations<br />

to use these data to guide local and global policymakers. This<br />

study group will provide an update <strong>of</strong> the GBD Study progress<br />

through presentations on systematic reviews <strong>of</strong> the global<br />

prevalence <strong>of</strong>, and DALYs associated MSK conditions. Global<br />

strategies for bridging gaps in the availability <strong>of</strong> MSK populationbased<br />

data and the inequity <strong>of</strong> access to evidence-based MSK<br />

health care and education will be discussed.<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• identify the key data required for the calculation <strong>of</strong> DALYs for<br />

MSK conditions<br />

• identify the regions <strong>of</strong> the world where population-based MSK<br />

data are deficient<br />

• explain the importance <strong>of</strong> collecting standardized MSK data<br />

from population-based health surveys<br />

• explain the principles involved in measuring equity and access<br />

to minimum standards <strong>of</strong> care for MSK conditions<br />

A315<br />

Joint Hypermobility Syndrome<br />

Moderators: Jaime F. Bravo, MD; Nuestra Sra de Los Angeles;<br />

Santiago, Chile<br />

Rodney Grahame, MD; University <strong>College</strong> Hospital; London,<br />

United Kingdom<br />

6:45 PM<br />

Are Some Joint Hypermobility Criteria More Closely Associated<br />

with Anxiety than Others?<br />

Antonio Bulbena, MD; Hospital del Mar and University; Bilbao,<br />

Spain<br />

7:00 PM<br />

Why is Joint Hypermobility Syndrome so Frequently Missed?<br />

Rodney Grahame, MD; University <strong>College</strong> Hospital; London,<br />

United Kingdom<br />

7:15 PM<br />

Treatment <strong>of</strong> Dysautonomia (Chronic Fatigue, Dizziness and<br />

Syncope)<br />

Jaime F. Bravo, MD; Nuestra Sra de Los Angeles; Santiago, Chile<br />

7:45 PM<br />

An Integrated Approach to the Physiotherapy Assessment and<br />

Management <strong>of</strong> Joint Hypermobility Syndrome<br />

Jane Simmonds, MCSP, MMACP; University <strong>of</strong> Herfordshire;<br />

Hatfield, Herfordshire, United Kingdom<br />

Session Overview:<br />

The interest about Joint Hypermobility Syndrome among<br />

rheumatologists has increased, but still in most cases the<br />

diagnosis <strong>of</strong> these patients is not made. There is a need not only<br />

to increase awareness about the condition, but also to learn<br />

how to treat these patients.<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• appreciate that anxiety is very frequently associated to JHS<br />

and explains many symptoms<br />

• explain that JHS is frequent also in children and that the<br />

diagnosis is seldom made<br />

• treat effectively patients with Dysautonomia, improving<br />

significantly the quality <strong>of</strong> life <strong>of</strong> these patients<br />

• appreciate the role <strong>of</strong> physiotherapy and other allied health<br />

pr<strong>of</strong>essionals in the management <strong>of</strong> hypermobility syndrome<br />

B310<br />

Kawasaki Disease in the 21st Century - Genes,<br />

Pathogenesis, and Biologics<br />

Moderators: Anne M. Stevens, MD, PhD; Pediatrics, University <strong>of</strong><br />

Washington; Seattle, WA<br />

Polly J. Ferguson, MD; University <strong>of</strong> Iowa Carver <strong>College</strong> <strong>of</strong><br />

Medicine; Iowa City, IA<br />

6:45 PM<br />

The Pathogenesis <strong>of</strong> Kawasaki Disease: Novel Insights from<br />

Genetics and Immunology<br />

Rae S.M. Yeung, MD, PhD; Hospital for Sick Children; Toronto,<br />

ON, Canada<br />

7:15 PM<br />

Novel Strategies for Treatment and Monitoring for Kawasaki<br />

Disease<br />

Robert P. Sundel, MD; Children’s Hospital Medical Center;<br />

Boston, MA<br />

7:35 PM<br />

ACR Pediatrics Section Business Meeting<br />

Marisa S. Klein-Gitelman, MD, MPH; Children’s Memorial<br />

Hospital/North Western University; Chicago, IL<br />

Session Overview:<br />

Kawasaki disease is one <strong>of</strong> the most common forms <strong>of</strong> vasculitis<br />

affecting children, with coronary artery sequelae leading into<br />

adult years. Over the past decade progress has been made<br />

in identifying patients with atypical Kawasaki disease and<br />

in managing patients resistant to standard therapy. Biologic<br />

immunosuppressive and anticoagulation treatments provide<br />

novel options for treatment. Further, genetic and immunologic<br />

studies provide new insights into the pathogenesis <strong>of</strong> Kawasaki<br />

disease. A better understanding <strong>of</strong> the evidence for treatment<br />

and the recent basic science advances will aid adult and<br />

pediatric rheumatologists in the care <strong>of</strong> patients with Kawasaki<br />

Disease.<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• recognize the signs and symptoms <strong>of</strong> typical and atypical KD<br />

and the risk factors for coronary aneurysms in children with<br />

fevers<br />

• describe the genes associated with Kawasaki disease risk, and<br />

hypotheses for pathogenesis<br />

• identify the indications for and recommendations for secondline<br />

immunosuppressive therapy for Kawasaki Disease<br />

patients who do not respond to IVIG, including corticosteroids,<br />

cyclophosphamide, and anti-TNF agents<br />

• know the evidence for recommendations for acute and<br />

chronic anticoagulation for KD<br />

A311<br />

Macrophage Activation Syndrome<br />

Moderators: Randy Q. Cron, MD, PhD; Children’s Hospital <strong>of</strong><br />

Alabama; Birmingham, AL<br />

Edward M. Behrens, MD; Children’s Hospital <strong>of</strong> Philadelphia;<br />

Philadelphia, PA<br />

90<br />

2010 Program Book

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