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B O O K - American College of Rheumatology

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MONDAY, NOVEMBER 8, 2010<br />

ACR/ARHP Registration<br />

6:30 am - 5:00 pm<br />

International Blvd. Foyer<br />

ARHP Special Sessions<br />

7:00 - 8:00 am<br />

B309<br />

First-Time Attendees Orientation<br />

First time ARHP annual meeting attendees are invited to an<br />

orientation to learn the ‘ins and outs’ <strong>of</strong> the annual meeting. The<br />

ARHP Membership and Nominations Committee will be on hand<br />

to provide advice to assist you in planning how to get the most<br />

out <strong>of</strong> your first annual meeting.<br />

This session is not eligible for CME credit. C<strong>of</strong>fee and tea will be<br />

provided.<br />

Moderator: Pamela J. Degotardi, PhD; Queens <strong>College</strong> City<br />

University <strong>of</strong> New York Honors; Flushing, NY<br />

B308<br />

Moderators Orientation<br />

This session is not eligible for CME credit. C<strong>of</strong>fee and tea will be<br />

provided.<br />

Moderator: Janet L. Poole, PhD, OTR; University <strong>of</strong> New Mexico;<br />

Albuquerque, NM<br />

ACR Basic Science Symposium<br />

7:15 - 8:45 am<br />

B402<br />

Molecular Mechanisms <strong>of</strong> Inflammatory Signaling in<br />

Cartilage Destruction R<br />

Moderators: Richard F. Loeser, MD; Wake Forest University;<br />

Winston-Salem, NC<br />

Anna H. Plaas, PhD; Rush University; Chicago, IL<br />

7:15 AM<br />

ESE:1: Transcriptional and Epigenetic Regulation <strong>of</strong> Cartilage<br />

Remodeling<br />

Mary B. Goldring, PhD; Hospital for Special Surgery; Weill Cornell<br />

Medical <strong>College</strong>; New York, NY<br />

7:45 AM<br />

Chemokines, Cytokines, and their Modulation During Joint<br />

Degeneration<br />

Qian Chen, PhD; Brown University, Rhode Island Hospital;<br />

Providence, RI<br />

8:15 AM<br />

Stimulation <strong>of</strong> Cartilage Destruction by S100 Proteins in<br />

Experimental Arthritis<br />

Peter Van Lent, MD; Radbound University Medical Centre;<br />

Nijmegen, Netherlands<br />

Session Overview:<br />

Cartilage destruction is a central feature <strong>of</strong> many types <strong>of</strong><br />

arthritis. Currently there are no therapies proven to slow or<br />

prevent cartilage destruction. An improved understanding <strong>of</strong><br />

the mechanisms <strong>of</strong> inflammatory signaling in cartilage will<br />

potentially lead to new therapeutic targets for diseases affecting<br />

cartilage, including osteoarthritis.<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• identify the role <strong>of</strong> transcription factors activated by<br />

inflammatory mediators in mediating cartilage destruction<br />

• assess the roles <strong>of</strong> chemokines and cytokines in cartilage<br />

matrix destruction<br />

• analyze the role <strong>of</strong> the S100 proteins, which include the<br />

alarmins, in mediating cartilage destruction<br />

ACR Clinical Symposium<br />

7:15 - 8:30 am<br />

Hall A3<br />

Year in Review c/r<br />

Moderator: Joel A. Block, MD; Rush University Medical Center;<br />

Chicago, IL<br />

7:15 AM<br />

Image Competition Presentation<br />

Alan N. Baer, MD, Audiovisual Aids Subcommittee Chair; Johns<br />

Hopkins University; Baltimore, MD<br />

7:30 AM<br />

Clinical Perspective<br />

Michael H. Weisman, MD; Cedars-Sinai Medical Center; Los<br />

Angeles, CA<br />

8:00 AM<br />

Basic Science Perspective<br />

John P. Atkinson, MD; Washington University School <strong>of</strong><br />

Medicine; St. Louis, MO<br />

Session Overview:<br />

<strong>Rheumatology</strong> is a rapidly advancing field, with substantive<br />

scientific breakthroughs being translated into clinical use<br />

constantly. Therefore, it is important for rheumatologist to<br />

maintain knowledge <strong>of</strong> the most important advances. During<br />

this session, leaders in the field will review and summarize the<br />

most important publications from the previous year in the basic<br />

science and the clinical practice <strong>of</strong> rheumatology.<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• discuss selected recent publications on the pathophysiological<br />

basis <strong>of</strong> rheumatic diseases by literature review <strong>of</strong> important<br />

publications<br />

• identify selected treatment modalities for rheumatic diseases<br />

from the recent published literature<br />

• enumerate how these new advances may impact the practice<br />

<strong>of</strong> rheumatology<br />

monday<br />

2010 Program Book 27

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