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B O O K - American College of Rheumatology

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ACR/ARHP Poster Session B<br />

200<br />

867. The Help <strong>of</strong> Autoantibody-Inducing CD4+ T Cell and Antigen<br />

Cross-Presentation Are Required for the Full-Maturation<br />

<strong>of</strong> Cytotoxic T Lymphocyte and Subsequent Lupus Kidney<br />

Disease. Yumi Miyazaki 1 , Ken Tsumiyama 1 and Shunichi<br />

Shiozawa 2 , 1 Department <strong>of</strong> Biophysics, Kobe University<br />

Graduate School <strong>of</strong> Health Science, Kobe, Japan, 2 Department <strong>of</strong><br />

Biophysics, Kobe University Graduate School <strong>of</strong> Health Science/<br />

Department <strong>of</strong> Medicine, Kobe University Graduate School <strong>of</strong><br />

Medicine/The Center for Rheumatic Diseases, Kobe University<br />

Hospital, Kobe, Japan.<br />

868. Unique Role <strong>of</strong> the FcγRI (CD64) Cytoplasmic Domain in<br />

Mediating Phosphorylation Dependent Lipid Raft Localization.<br />

Andrew G. Gibson 3 , Xinrui Li 3 , Jeffrey C. Edberg 2 and Robert<br />

P. Kimberly 1 , 1 Univ Alabama at Birmingham, Birmingham,<br />

AL, 2 University <strong>of</strong> Alabama at Birmingham, Birmingham, AL,<br />

3<br />

University <strong>of</strong> Alabama at Birmingham.<br />

Metabolic and Crystal Arthropathies - Pathogenesis, Epidemiology,<br />

and Clinical Manifestations II<br />

869. A Prospective Study <strong>of</strong> Correlates <strong>of</strong> Axial Gout. Rukmini<br />

M. Konatalapalli 4 , Elena Lumezanu 3 , James Jelinek 3 , Mark<br />

Murphey 1 , Elizabeth Carter 2 and Arthur Weinstein 3 , 1 Armed<br />

Force Institute, 2 Medstar Health Research Institute, 3 Washington<br />

Hospital Center, 4 Washington Hospital Center, DC.<br />

870. Acute Gout Results in Increased Plasma Myeloperoxidase: A<br />

Potential Mechanism for Increase Cardiovascular Risk? Lisa K.<br />

Stamp 1 , Irada Khalilova 2 and Tony Kettle 2 , 1 University <strong>of</strong> Otago,<br />

Christchurch, New Zealand, 2 University <strong>of</strong> Otago.<br />

871. A-SAA Induces Cytokine Production and Matrix<br />

Metalloproteinase Activity in Adipose and RA Synovial Tissue.<br />

Jennifer McCormick, Ronan M. Mullan, Mary Connolly, Chin<br />

Teck Ng, Ursula Fearon and Douglas J. Veale, Dublin Academic<br />

Medical Centre, Dublin, Ireland.<br />

872. Association <strong>of</strong> Vitamin K and Chondrocalcinosis <strong>of</strong> the Knee:<br />

The MOST and Framingham Osteoarthritis Studies. Devyani<br />

Misra 3 , Sarah L. Booth 8 , Micheal LaValley 3 , Irina Toltsykh 6 ,<br />

Micheal Nevitt 6 , C. Elizabeth Lewis 5 , James Torner 7 , Piran<br />

Aliabadi 4 , David T. Felson 2 and Tuhina Neogi 1 , 1 Boston Univ Schl<br />

<strong>of</strong> Med, Boston, MA, 2 Boston University School <strong>of</strong> Medicine,<br />

Boston, MA, 3 BUSM, Boston, MA, 4 BWH, Harvard University,<br />

Boston, MA, 5 UAB, Birmingham, AL, 6 UCSF, San Francisco, CA,<br />

7<br />

U-Iowa, Iowa City, IA, 8 USDA HNRCA, Tufts University, Boston,<br />

MA.<br />

873. Calcium Pyrophosphate Crystal Arthritis (CPPA) Is a Frequent<br />

Cause <strong>of</strong> “Refractory Gout”. Fernando Perez-Ruiz 1 , Ana M.<br />

Herrero-Beites 3 , Alberto Alonso-Ruiz 2 and Marcelo Calabozo 2 ,<br />

1<br />

Hospital de Cruces, Jopelana, Spain, 2 Hospital de Cruces,<br />

3<br />

Hospital de Górliz.<br />

874. Clinical and Genetic Subtypes <strong>of</strong> Hyperuricemia in a Renal<br />

Transplant Cohort. Gabriela Hernandez-Molina, Julio Granados,<br />

Adriana Torres, Antonio Cachafeiro-Vilar and Marina Rull-<br />

Gabayet, Instituto Nacional de Ciencias Medicas y Nutricion,<br />

Mexico City, Mexico.<br />

875. Diffuse Calcium-Containing Crystal Deposits in Human<br />

Osteoarthritic Articular Cartilage: Not Limited to the Medial<br />

Compartment. Christelle Nguyen 4 , Hang-Korng Ea 4 , Didier<br />

Hannouche 2 , Michel Daudon 3 , Dominique Bazin 1 and Frédéric<br />

Lioté 4 , 1 Laboratoire de Physique des Solides; Paris Sud<br />

University; Orsay; France, 2 Orthopaedic Surgery Department;<br />

Lariboisière Hospital; Paris Diderot University; Assistance<br />

Publique-Hôpitaux de Paris (AP-HP), Paris, 3 Service de Biochimie<br />

A; Necker Hospital; Paris Sud University; AP-HP; Paris, 4 UMR-S<br />

606, INSERM & Paris Diderot University; PRES Sorbonne Paris-<br />

Cite; Lariboisiere Hospital; Paris; France.<br />

2010 Program Book<br />

876. Factors Associated with an Acute Attack <strong>of</strong> Chronic Gout<br />

without Hyperuricemia. MinWook So 1 , SeungGeun Lee 3 ,<br />

YongGil Kim 3 , ChangKeun Lee 3 , HeeBom Moon 3 , Jiseon Oh 4 and<br />

Bin Yoo 2 , 1 ASAN Medical Ctr, Seoul, Korea, Republic <strong>of</strong>, 2 ASAN<br />

Medical Ctr, Seoul, Korea, Republic <strong>of</strong>, 3 ASAN Medical Ctr, 4 Ulsan<br />

University.<br />

877. Hyperuricemia and Gout: Nature Versus Nurture. Eswar<br />

Krishnan 3 , Christina N. Lessov-Schlaggar 4 , James F. Fries 2 , Ruth<br />

Krasnow 1 and Gary E. Swan 1 , 1 SRI International, 2 Stanford Univ<br />

Medical Ctr, Palo Alto, CA, 3 Stanford University, Palo Alto, CA,<br />

4<br />

WUSTL.<br />

878. Hyperuricemia as a Risk Factor for Hypertension among Young<br />

Adults without Metabolic Syndrome. Eswar Krishnan 1 , Bhavik<br />

Pandya 2 , Ali Hariri 3 and Omar Dabbous 2 , 1 Stanford University<br />

School <strong>of</strong> Medicine, Stanford, CA, 2 Takeda Pharmaceuticals<br />

International, Inc, Deerfield, IL, 3 Takeda Pharmaceuticals North<br />

America, Inc, Deerfield, IL.<br />

879. Individuals in the US General Population with Gout and<br />

Hyperuricemia Have Significantly Higher Comorbidities: The<br />

National Health and Nutrition Examination Survey (NHANES)<br />

2007-2008. Bhavik Pandya 2 , Yanyan Zhu 1 and Hyon Choi 1 ,<br />

1<br />

Boston University <strong>of</strong> School <strong>of</strong> Medicine, Boston, MA, 2 Takeda<br />

Pharmaceuticals International, Inc, Deerfield, IL.<br />

880. Low Prevalence <strong>of</strong> Coexistent Gout and Rheumatoid Arthritis<br />

in a Population <strong>of</strong> Veterans. Armine Tumyan 1 , Kara H. Prescott 2<br />

and Andreas M. Reimold 1 , 1 Dallas VA Medical Center and Univ <strong>of</strong><br />

TX Southwestern Med Ctr, Dallas, TX, 2 Dallas VA Medical Center<br />

and Univ <strong>of</strong> TX Southwestern Med Ctr, Cross Roads, TX.<br />

881. Monosodium Urate Monohydrate Crystals Inhibit Osteoblast<br />

Viability and Differentiation: Implications for Development <strong>of</strong><br />

Bone Erosion in Chronic Gout. Ashika Chhana 2 , Karen Callon 2 ,<br />

Bregina Pool 2 , Dorit Naot 2 , Fiona M. McQueen 2 , Jillian Cornish 2<br />

and Nicola Dalbeth 1 , 1 Univ Auckland, Auckland, New Zealand,<br />

2<br />

University <strong>of</strong> Auckland, Auckland, New Zealand.<br />

882. Number <strong>of</strong> Flares Are Associated with Both Gastrointestinal<br />

and Vascular Complications in Patients with Gout. Another<br />

Issue for Early Intervention. Fernando Perez-Ruiz 1 , Ana M.<br />

Herrero-Beites 2 and Miguel A. Gonzalez-Gay 3 , 1 Hospital de<br />

Cruces, Spain, 2 Hospital de Górliz, Spain, 3 Hospital Universitario<br />

Marqués de Valdecilla, Spain.<br />

883. Patients with Gout May Have a Decreased Risk <strong>of</strong> Colonic<br />

Polyps Relative to Patients with Osteoarthritis (OA): Insights<br />

from the NY VA Gout Database. Aaron Lehmann 3 , Laura<br />

Schneck 4 , Robert T. Keenan 1 , William O’Brien 2 , Daria Crittenden 2 ,<br />

Kristen Lee 2 , Rekha Tadoori, Fritz Francois 2 and Michael H.<br />

Pillinger 4 , 1 Duke University, Durham, NC, 2 NYU Langone Medical<br />

Center, 3 NYU Langone Medical Center, Flushing, NY, 4 NYU<br />

Langone Medical Center, New York, NY.<br />

884. P-Homocysteine Levels Are Independently Correlated to<br />

S-Urate but Not to Urate Lowering Treatment. Results <strong>of</strong> an<br />

Observational Study <strong>of</strong> 112 Patients with Gout. Ole Slot, Dept.<br />

<strong>of</strong> <strong>Rheumatology</strong>, Copenhagen University Hospital, Glostrup,<br />

Denmark.<br />

885. Rates <strong>of</strong> Meniscal Tearing Seen on Arthroscopy <strong>of</strong> Patients<br />

with Chondrocalcinosis. William Chun 1 , Humaira Hussain 3 ,<br />

Vincent J. Zarro 1 , Carolyn R. O’Connor 1 and Angel E. Checa 2 ,<br />

1<br />

Drexel University <strong>College</strong> <strong>of</strong> Medicine, Philadelphia, PA,<br />

2<br />

Drexel University <strong>College</strong> <strong>of</strong> Medicine, Cherry Hill, NJ, 3 Drexel<br />

University <strong>College</strong> <strong>of</strong> Medicine.

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