B O O K - American College of Rheumatology
B O O K - American College of Rheumatology
B O O K - American College of Rheumatology
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ACR Poster Session B<br />
214<br />
1070. Anticitrullinated Peptide Antibodies (ACPAS) in the Sera<br />
<strong>of</strong> Heavy Smokers without Arthritis. A Differential Role <strong>of</strong><br />
Associated Pulmonary Disease? Virginia Ruiz-Esquide 3 , María<br />
José Gómara 4 , Víctor Peinado 1 , José Alfredo Gómez Puerta 3 ,<br />
María Victoria Hernández 2 , Joan A. Barberà 1 , Julio Ramírez 3 ,<br />
Juan de Dios Cañete 3 , Isabel Haro 4 and Raimon Sanmartí 3 ,<br />
1<br />
Pneumology Service, Hospital Clínic <strong>of</strong> Barcelona, Barcelona,<br />
Spain, 2 <strong>Rheumatology</strong> Service, Hospital Clínic <strong>of</strong> Barcelona,<br />
Barcelona, Spain, 3 <strong>Rheumatology</strong> Service. Hospital Clínic <strong>of</strong><br />
Barcelona, Barcelona, Spain, 4 Unit <strong>of</strong> Synthesis and Biomedical<br />
Applications <strong>of</strong> Peptides, IQAC-CSIC, Barcelona, Spain.<br />
1071. Anti-Citrullinated Protein Antibodies (ACPA) in Unaffected<br />
Siblings <strong>of</strong> ACPA-Positive Rheumatoid Arthritis Patients. Lillian<br />
Barra 1 , Elizabeth Wilson 1 , Matthias Scinocca 1 , Kelly Summers 1 ,<br />
Ewa Cairns 2 and David A. Bell 2 , 1 The University <strong>of</strong> Western<br />
Ontario, 2 The University <strong>of</strong> Western Ontario, London, ON,<br />
Canada.<br />
1072. Atherogenic Properties <strong>of</strong> Rheumatoid Arthritis Plasma:<br />
Effect on Cholesterol Transport Genes. Allison B. Reiss 1 ,<br />
Iryna Voloshyna 1 , Michael Littlefield 1 , Elise Belilos 1 , Kristina<br />
Belostocki 2 , Lois A. Bonetti 1 , Gary C. Rosenblum 1 and Steven E.<br />
Carsons 1 , 1 Winthrop University Hospital, Mineola, NY, 2 Winthrop<br />
University Hospital, Jamaica, NY.<br />
1073. Circulating Cytokines Influence the Fetal Growth in Pregnant<br />
Women with Rheumatoid Arthritis. Florentien D. O. de<br />
Steenwinkel 2 , Johanna M. W. Hazes 1 , Yaël A. de Man 1 , Anita C.<br />
S. Hokken 2 , Yolanda B. de Rijke 2 and Radboud J. E. M. Dolhain 1 ,<br />
1<br />
Erasmus Medical Center, Rotterdam, The Netherlands,<br />
2<br />
Erasmus Medical Center/Sophia Children’s Hospital, Rotterdam,<br />
The Netherlands.<br />
1074. Citrullination and Peptidylarginine Deiminase (PAD) Expression<br />
Is Detected in the Oral Mucosa and Periodontium in the<br />
Absence <strong>of</strong> Rheumatoid Arthritis. Clifton O. Bingham 1 , Mark A.<br />
Reynolds 3 , Jon Giles 2 , Felipe Andrade 2 , Joan M. Bathon 2 , Karen<br />
Fox-Talbot 2 and Marc K. Halushka 2 , 1 Johns Hopkins, Baltimore,<br />
MD, 2 Johns Hopkins, 3 University <strong>of</strong> Maryland Dental School.<br />
1075. Common Genetic Background for Rheumatoid Arthritis and<br />
Systemic Lupus Erythematosus. Gisela Orozco, Steve Eyre, Anne<br />
Hinks, Wendy Thomson, Jane Worthington and Anne Barton,<br />
Arthritis Research Campaign Epidemiology Unit, The University<br />
<strong>of</strong> Manchester.<br />
1076. Confirmation <strong>of</strong> the Especial Interaction <strong>of</strong> Autoimmunity<br />
Against Citrullinated α-Enolase with Genotypes Predisposing<br />
to Rheumatoid Arthritis. Antonio Gonzalez 1 , Ariana Montes 2 ,<br />
Rebeca Dieguez-Gonzalez 2 , Manuel Calaza 2 , Eva Perez-Pampin 2 ,<br />
Antonio Mera 2 and Juan J. Gomez-Reino 2 , 1 Hospital Clinico<br />
Universitario de Santiago, Santiago de Compostela, A Coruña,<br />
Spain, 2 Hospital Clinico Universitario de Santiago.<br />
1077. C-Reactive Protein (CRP) Single Nucleotide Polymorphisms<br />
(SNPs) Are Associated with Radiographic Damage and Plasma<br />
CRP Levels in African <strong>American</strong>s (AAs) with Early Rheumatoid<br />
Arthritis (RA). Maria I. Danila 6 , Lang Chen 5 , Desiree M. Van<br />
Der Heijde 2 , Doyt L. Conn 1 , Beth L. Jonas 7 , Leigh F. Callahan 8 ,<br />
Edwin A. Smith 3 , Richard Brasington 10 , Larry W. Moreland 9 , S.<br />
Louis Bridges 6 and Laura B. Hughes 4 , 1 Emory Univ Schl <strong>of</strong> Med,<br />
Atlanta, GA, 2 Leiden University Medical Center, Meerssen, The<br />
Netherlands, 3 Med Univ <strong>of</strong> South Carolina, Charleston, SC, 4 Univ<br />
<strong>of</strong> Alabama Birmingham, Birmingham, AL, 5 Univ <strong>of</strong> Alabama-<br />
Birmingham, 6 Univ <strong>of</strong> Alabama-Birmingham, Birmingham,<br />
AL, 7 Univ <strong>of</strong> N Carolina-Chapel Hill, Chapel Hill, NC, 8 Univ <strong>of</strong><br />
North Carolina, Chapel Hill, NC, 9 Univ <strong>of</strong> Pittsburgh Med Ctr,<br />
Pittsburgh, PA, 10 Washington Univ Schl <strong>of</strong> Med, St Louis, MO.<br />
2010 Program Book<br />
1078. Differential Association <strong>of</strong> IL23R Genetic Variants with Anti-<br />
CCP Positive and Negative Rheumatoid Arthritis Patients.<br />
Antonio Gonzalez 6 , Aida Ferreiro 5 , Eva Perez-Pampin 5 , Manuel<br />
Calaza 5 , Francisco J. Lopez-Longo 13 , Jose Luis Marenco 12 ,<br />
Francisco J. Blanco 9 , Rafael Caliz 14 , Javier Narvaez 10 , Federico<br />
Navarro 15 , Juan Cañete 3 , Arturo R. de la Serna 8 , Isidoro<br />
Gonzalez-Alvarez 11 , Gabriel Herrero-Beaumont 1 , Jose Luis<br />
Pablos 2 , Alejandro Balsa 7 , Benjamin Fernandez-Gutierrez 4<br />
and Juan J. Gomez-Reino 5 , 1 Fundacion Jimenez Diaz. Madrid,<br />
2<br />
Hospital 12 de Octubre, Madrid, 3 Hospital Clinic. Barcelona,<br />
4<br />
Hospital Clinico San Carlos, Madrid, 5 Hospital Clinico<br />
Universitario de Santiago, 6 Hospital Clinico Universitario de<br />
Santiago, Santiago de Compostela, Spain, 7 Hospital La Paz .<br />
Madrid, 8 Hospital Santa Creu e San Pau. Barcelona, 9 Hospital<br />
Universitario A Coruña, 10 Hospital Universitario de Bellvitge.<br />
Barcelona, 11 Hospital Universitario de la Princesa, 12 Hospital<br />
Universitario de Valme. Sevilla, 13 Hospital Universitario Gregorio<br />
Marañon, Madrid, 14 Hospital Universitario Virgen de las Nieves,<br />
Granada, 15 Hospital Universitario Virgen Macarena, Sevilla.<br />
1079. DNA Damage, T Cell Lymphopenia and Immunosenescence in<br />
Rheumatoid Arthritis. Lan Shao 1 , Hiroshi Fujii 2 , Jorg J. Goronzy 1<br />
and Cornelia M. Weyand 1 , 1 Stanford University School <strong>of</strong><br />
Medicine, Stanford, CA, 2 Tohoku University School <strong>of</strong> Medicine,<br />
Sendai, Japan.<br />
1080. Do Patients with Rheumatoid Arthritis Exhibit Differential<br />
Cellular Responses to Implant Wear Debris and Do the Implant<br />
Failure Mechanisms Differ from Non-RA Patients? Anant<br />
Vasudevan 5 , Edward F. DiCarlo 3 , Timothy Wright 2 , Dan Chen 2 ,<br />
Steven R. Goldring 1 and Lisa A. Mandl 4 , 1 Chief Scientific Officer,<br />
Hospital for Special Surgery, 2 Department <strong>of</strong> Biomechanics,<br />
Hospital for Special Surgery, 3 Department <strong>of</strong> Pathology and<br />
Laboratory Medicine, Hospital for Special Surgery, 4 Hospital for<br />
Special Surgery, New York, NY, 5 Yale School <strong>of</strong> Medicine, New<br />
York, NY.<br />
1081. Dual Roles <strong>of</strong> Heme Oxygenase-1 on Rheumatoid Arthritis:<br />
Anti-Inflammation Versus Angiogenesis. Kaoru Takase 2 , Shigeru<br />
Ohno 1 , Mitsuhiro Takeno 3 and Yoshiaki Ishigatsubo 4 , 1 Center for<br />
Rheumatic Diseases, Yokohama City University Medical Center,<br />
2<br />
Department <strong>of</strong> Internal Medicine and Clinical Immunology,<br />
Yokohama City University Graduate School <strong>of</strong> Medicine, Japan,<br />
3<br />
Department <strong>of</strong> Internal Medicine and Clinical Immunology,<br />
Yokohama City University Graduate School <strong>of</strong> Medicine, Japan<br />
4<br />
Yokohama City Grad Sch <strong>of</strong> Med, Yokohama, Japan.<br />
1082. Epstein Barr Virus Serologies and Future Risk <strong>of</strong> Rheumatoid<br />
Arthritis among Women. Barbara L. Goldstein 2 , Lori B. Chibnik 2 ,<br />
Elizabeth W. Karlson 2 and Karen H. Costenbader 1 , 1 Brigham &<br />
Women, Boston, MA, 2 Brigham and Women’s Hospital, Boston,<br />
MA.<br />
1083. Expanded Cytokine/Chemokine Testing Improves Prediction<br />
<strong>of</strong> Time to Future Diagnosis <strong>of</strong> Seropositive Rheumatoid<br />
Arthritis (RA) in an Age-Dependent Manner. Kevin D. Deane 8 ,<br />
Colin I. O’Donnell 2 , Lezlie A. Derber 3 , Jess D. Edison 10 , William<br />
R. Gilliland 1 , Wolfgang Hueber 4 , Jeremy Sokolove 6 , Piyanka E.<br />
Chandra 7 , Jill Norris 9 , William Robinson 5 and V. Michael Holers 8 ,<br />
1<br />
Department <strong>of</strong> Medicine, <strong>Rheumatology</strong> Section, Walter<br />
Reed Army Medical Center, Washington, DC, 2 Department <strong>of</strong><br />
Preventive Medicine and Biometrics, University <strong>of</strong> Colorado<br />
Denver, Denver, CO, 3 Division <strong>of</strong> <strong>Rheumatology</strong>, University <strong>of</strong><br />
Colorado School <strong>of</strong> Medicine, Aurora, CO, 4 Novartis Institutes<br />
for BioMedical Research, Basel, Switzerland, 5 Stanford Univ<br />
School <strong>of</strong> Med, Stanford, CA, 6 Stanford University School <strong>of</strong><br />
Medicine, Palo Alto, Mountain View, CA, 7 Stanford University<br />
School <strong>of</strong> Medicine, Palo Alto, CA, 8 Univ <strong>of</strong> Colorado School <strong>of</strong><br />
Med, Aurora, CO, 9 University <strong>of</strong> Colorado Denver, Aurora, CO,<br />
10<br />
Walter Reed Army Med Ctr, Washington, DC.