B O O K - American College of Rheumatology

ACR Poster Session A
441. Recombinant Chaperonin 10 Suppresses Cutaneous Lupus and
Lupus Nephritis in MRL-(Fas)lpr Mice. Onkar P. Kulkarni 3 , Mi
Ryu 3 , Claudia Kantner 3 , Miklos Sardy 2 , Dean Naylor 1 , Richard
Brown 1 , Daina Vanags 1 and Hans-Joachim Anders 3 , 1 CBio Ltd,
Eight Mile Plains, Queensland, Australia, 2 Department of
Dermatology and Allergology, University of Munich, Munich,
Germany, 3 Medizinische Poliklinik-Innenstadt, University of
Munich, Munich, Germany.
442. TGF-β-Induced CD4+Foxp3+ Cells Suppress Lupus-Like
Syndrome through Induction of Formation of Tolerogenic
DC. Xiaohui Zhou 4 , Julie Wang 4 , David A. Horwitz 2 , Huimin
Fan 3 , Hejian Zou 1 , Zhongmin Liu 3 and Song Guo Zheng 4 , 1 Fudan
University Medical School, 2 LAC/USC Medical Center, Los
Angeles, CA, 3 Tongji University Medical School, 4 University of
Southern California.
443. Widespread Upregulation of mEPCR in Kidney, Spleen
and Liver of a Nephritic NZM B/W F1: Implications to
Microvascular Disease. Sherry Xu 1 and Robert M. Clancy 2 , 1 NYU
School of Medicine, 2 Tisch Hospital 4 - 407 , New York, NY.
Systemic Lupus Erythematosus - Clinical Aspects and Treatment I
444. Anti C1q Antibodies in Patients with Systemic Lupus
Erythematosus and Cutaneous Vasculitis: A Controlled Study.
Shirish R. Sangle 1 , Loh Yet Lin 2 , Esther Sanchez 2 , Davies Rachel 2
and David P. D’Cruz 2 , 1 St Thomas’ Hospital, London, United
Kingdom, 2 St Thomas’ Hospital, United Kingdom.
445. Antimalarials May Attenuate the Risk of Metabolic Syndrome
in SLE: Results from an International Imception Cohort
Registry. M. H. X. Ting 2 , R. P. Donn 3 , M. Lunt 3 , M. B. Urowitz 4 ,
D. D. Gladman 1 , D. Ibanez 1 , C. Gordon 1 , S. C. Bae 1 , A. Clarke 1 ,
S. Bernatsky 1 , J. Hanly 1 , D. Isenberg 1 , A. Rahman 1 , J. Sanchez-
Guerrero 1 , J. Romero-Diaz 1 , P. R. Fortin 1 , D. Wallace 1 , E. Ginzler 1 ,
A. Vasudevan 1 , J. Merrill 1 , G. S. Alarcon 1 , B. Fessler 1 , G. Sturfelt 1 ,
O. Nived 1 , K. Steinsson 1 , M. Khamashta 1 , M. Petri 1 , S. Manzi 1 , M.
Dooley 1 , R. Ramsey-Goldman 1 , C. Aranow 1 , R. Van Vollenhoven 1 ,
M. Ramos 1 , T. Stoll 1 , K. Kalunian 1 , A. Zoma 1 , P. Maddison 1 and I.
N. Bruce 3 , 1 Systemic Lupus International Collaborating Clinics,
Toronto, ON, Canada, 2 The University of Manchester, Salford,
Manchester, United Kingdom, 3 The University of Manchester,
4
Toronto Western Hospital, Toronto, ON, Canada.
446. Arthritis in an Ethnically Diverse Systemic Lupus
Erythematosus Population. Guada Respicio 1 , Clare Cleveland 1 ,
Kim Taylor 1 and Lindsey A. Criswell 2 , 1 Rosalind Russell Medical
Research Center for Arthritis, University of California, San
Francisco, San Francisco, CA, 2 UCSF-Box 0500, San Francisco, CA.
447. Association of Low-Dose Pulsed Intravenous
Cyclophosphamide Therapy and Amenorrhea in 62 Patients
with Systemic Lupus Erythematosus: A Case-Control Study.
Sayumi Baba 1 , Yasuhiro Katsumata 4 , Yasushi Kawaguchi 2 , Kae
Takagi 1 , Takahisa Gono 1 , Yuko Okamoto 1 , Yuko Ota 1 , Masako
Hara 1 and Hisashi Yamanaka 3 , 1 Tokyo Women’s Medical
University, Tokyo, Japan, 2 Tokyo Women’s Medical University,
Tokyo, Japan, 3 Tokyo Women’s Medical University, Shinjuku-ku,
Tokyo, Japan, 4 Tokyo Women’s Medical University.
448. Atherosclerotic Vascular Events in a Multinational Inception
Cohort of SLE: Description and Attribution over an 8 Year
Period. Murray B. Urowitz 33 , Dafna D. Gladman 22 , Dominique
Ibanez 32 , Caroline P. Gordon 29 , Sang-Cheol Bae 6 , Ann E.
Clarke 15 , Sasha R. Bernatsky 15 , F. Jorge Sanchez-Guerrero 9 ,
John G. Hanly 19 , David A. Isenberg 24 , Anisur Rahman 25 , Paul R.
Fortin 33 , Daniel J. Wallace 1 , Ellen M. Ginzler 20 , Joan T. Merrill 18 ,
Graciela S. Alarcón 28 , Barri J. Fessler 23 , Ian N. Bruce 13 , Gunnar
K. Sturfelt 27 , Ola Nived 27 , Kristjan Steinsson 12 , Munther A.
Khamashta 21 , Michelle A. Petri 2 , Rosalind Ramsey-Goldman 17 ,
Susan Manzi 34 , Mary Anne Dooley 31 , Ronald V. Vollenhoven 11 ,
Cynthia B. Aranow 4 , Thomas Stoll 10 , Manuel Ramos 7 , Kenneth
C. Kalunian 26 , Asad A. Zoma 5 , Guillermo Ruiz-Irastorza 8 , Peter
J. Maddison 16 , Diane L. Kamen 14 , S. Sam Lim 3 and Christine A.
Peschken 30 , 1 West Hollywood, CA, 2 Timonium, MD, 3 Emory
University, Atlanta, GA, 4 Feinstein Institute, Manhasset, NY,
5
Hairmyres Hospital, East Kilbride, United Kingdom, 6 Hanyang
University Medical Center, Seoul, Korea, Republic of, 7 Hospital
Clinico I Provincial, Spain, 8 Hospital de Cruces, Universidad
del Pais Vasco, Spain, 9 Instituto Nacional Nutricion, Mexico
City, DF, Mexico, 10 Kantonsspital Schaffhausen, Schaffhausen,
Switzerland, 11 Karolinska University Hospital, Sweden,
12
Landspitalinn University Hospital, Iceland, 13 Manchester Royal
Infirmary, Manchester, United Kingdom, 14 Medical University
of South Carolina, Charleston, SC, 15 Montreal General Hospital,
Montreal, QC, Canada, 16 North West Whales NHS Trust, Colwyn
Bay, United Kingdom, 17 Northwestern University, Chicago, IL,
18
Oklahoma Med Research Foundation, Oklahoma City, OK,
19
Queen Elizabeth II Health Services Center, Halifax, NS, Canada,
20
SUNY-Downstate Medical Center, Brooklyn, NY, 21 The Rayne
Institute, London, United Kingdom, 22 Toronto Western Hospital,
Toronto, ON, Canada, 23 UAB Rheumatology, Birmingham, AL,
24
UCL Div of Medicine, London, United Kingdom, 25 UCL Div of
Medicine, United Kingdom, 26 UCSD School of Medicine, La Jolla,
CA, 27 University Hospital Lund, Lund, Sweden, 28 University of
Alabama, Oakland, CA, 29 University of Birmingham, Birmingham,
United Kingdom, 30 University of Manitoba, Winnipeg, MB,
Canada, 31 University of North Carolina, Chapel Hill, NC,
32
University of Toronto Lupus Clinic, Toronto Western Hospital,
33
University of Toronto Lupus Clinic, Toronto Western Hospital,
Toronto, ON, Canada, 34 West Penn Allegheny Health System,
Pittsburgh, PA.
449. Attention Deficit and Hyperactivity Disorder Scores Are
Elevated and Associated with Disease Activity and Fatigue in
Patients with Systemic Lupus Erythematosus. Ricardo J. Garcia,
Lisa Francis, Maha Dawood, Irene Ramos, Stephen Faraone and
Andras Perl, SUNY.
450. Autoantibody Response to Adjuvant and Non-Adjuvant H1N1
Vaccination in SLE. Murray B. Urowitz, Anoja Anton, Domonique
Ibañez and Dafna D. Gladman, Toronto Western Hospital,
Toronto, ON, Canada, Toronto Western Hospital, Toronto, ON,
Canada.
451. Belimumab, a BLyS-Specific Inhibitor, Reduced Corticosteroid
Use in Patients with Active SLE: Results from the Phase 3
BLISS-52 and -76 Studies. R. F. van Vollenhoven 9 , A. Gallacher 3 ,
S. Navarra 11 , E. M. Ginzler 8 , M. A. Dooley 10 , R. Cervera 4 , E. K. Li 2 ,
R. A. Levy 5 , R. Gúzman 7 , Z. J. Zhong 6 , S. Cooper 6 , L. Pineda 6 , D.
Hough 6 , D. J. Wallace 1 and for the BLISS- 52 and - 76 Study Groups,
1
Cedars-Sinai/UCLA, Los Angeles, CA, 2 Chinese University of
Hong Kong, Hong Kong, China, 3 Hospital Británico de Buenos
Aires, Argentina, 4 Hospital Clinic, Barcelona, Spain, 5 Hospital
Universitário Pedro Ernesto, Rio de Janeiro, Brazil, 6 Human
Genome Sciences, Inc, Rockville, MD, 7 SaludCoop, Bogotá,
Colombia, 8 SUNY Downstate Medical Center, Brooklyn, NY, 9 The
Karolinska Institute, Stockholm, Sweden, 10 University of North
Carolina at Chapel Hill, Chapel Hill, NC, 11 University of Santo
Tomas Hospital, Manila, Philippines.
2010 Program Book 177