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B O O K - American College of Rheumatology

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ACR/ARHP Poster Session C<br />

1583. Association <strong>of</strong> PPP2CA Polymorphisms with SLE Susceptibility<br />

in Multiple Ethnic Groups. Wenfeng Tan 15 , Jian Zhao 15 , Yun<br />

Deng 15 , Kenneth M. Kaufman 2 , Jennifer A. Kelly 1 , Sang-Cheol<br />

Bae 5 , Deh-Ming Chang 9 , Yeong Wook Song 13 , Chack-Yung<br />

Yu 14 , Robert P. Kimberly 11 , Marta E. Alarcón-Riquelme 12 ,<br />

John B. Harley 4 , Chaim O. Jacob 17 , Timothy J. Vyse 6 , Timothy<br />

B. Niewold 16 , Patrick M. Gaffney 10 , Kathy L. Moser 10 , Judith<br />

A. James 10 , Gary S. Gilkeson 7 , Diane L. Kamen 8 , Jennifer M.<br />

Grossman 15 , Bevra H. Hahn 15 , George C. Tsokos 3 and Betty P.<br />

Tsao 15 , 1 Arthritis and Immunology Program, Oklahoma Medical<br />

Research Foundation, 2 Arthritis and Immunology Program,<br />

Oklahoma Medical Research Foundation and US Department <strong>of</strong><br />

Veterans Affairs Medical Center, 3 Beth Israel Deaconess Medical<br />

Center, Harvard Medical School, 4 Cincinnati Children’s Hospital<br />

Medical Center and US Department <strong>of</strong> Veterans Affairs Medical<br />

Center, 5 Hanyang University, Korean, 6 Imperial <strong>College</strong> London,<br />

Hammersmith Hospital, London, UK, 7 Medical University <strong>of</strong><br />

South Carolina, 8 Medical University <strong>of</strong> South Carolina,, 9 National<br />

Defense Medical Center, Taipei, Taiwan, 10 Oklahoma Medical<br />

Research Foundation, 11 On Behalf <strong>of</strong> PROFILE Investigators,<br />

University <strong>of</strong> Alabama, 12 On Behalf <strong>of</strong> the BIOLUPUS and GENLES<br />

Networks, Uppsala University, Sweden, Center for Genomics<br />

and Oncological Research, Granada, Spain, Oklahoma Medical<br />

Research Foundation, 13 Seoul National University, Seoul, Korea,<br />

14<br />

The Ohio State University, 15 University <strong>of</strong> California, Los<br />

Angeles, CA, 16 University <strong>of</strong> Chicago, 17 University <strong>of</strong> Southern<br />

California.<br />

1584. Association <strong>of</strong> Variants in the TLR7-TLR8 Region with Systemic<br />

Lupus Erythematosus in Non-Asian Populations. Yun Deng 8 ,<br />

Jian Zhao 8 , Wenfeng Tan 8 , Kenneth M. Kaufman 2 , Elizabeth E.<br />

Brown 7 , Jeffrey C. Edberg 7 , Diane L. Kamen 6 , Gary S. Gilkeson 10 ,<br />

Chaim O. Jacob 10 , Robert H. Sc<strong>of</strong>ield 2 , Robert P. Kimberly on<br />

behalf <strong>of</strong> PROFILE Investigators 7 , Carl D. Langefeld 12 , Jennifer A.<br />

Kelly 1 , Marta E. Alarcón-Riquelme on Behalf <strong>of</strong> the BIOLUPUS<br />

and GENLES Networks 3 , John B. Harley 4 , Timothy J. Vyse 5 , Barry<br />

I. Freedman 11 , Patrick M. Gaffney 2 , Kathy L. Moser 2 , Judith<br />

A. James 2 , Timothy B. Niewold 9 , Jennifer M. Grossman 8 , Rita<br />

M. Cantor 8 , Bevra H. Hahn 8 and Betty P. Tsao 8 , 1 Arthritis and<br />

Immunology Program, Oklahoma Medical Research Foundation,<br />

Oklahoma City, OK, 2 Arthritis and Immunology Program,<br />

Oklahoma Medical Research Foundation, Oklahoma City, OK;<br />

University <strong>of</strong> Oklahoma Health Sciences Center, Oklahoma<br />

City, OK; US Department <strong>of</strong> Veterans Affairs Medical Center,<br />

Oklahoma City, OK, 3 Center for Genomics and Oncological<br />

Research, Granada, Spain, 4 Cincinnati Children’s Hospital<br />

Medical Center and US Department <strong>of</strong> Veterans Affairs Medical<br />

Center, Cincinnati, OH, 5 Imperial <strong>College</strong> London, Hammersmith<br />

Hospital, London, United Kingdom, 6 Medical University <strong>of</strong> South<br />

Carolina, Charleston, SC, 7 University <strong>of</strong> Alabama, Birmingham,<br />

AL, 8 University <strong>of</strong> California, Los Angeles, CA, 9 University <strong>of</strong><br />

Chicago, Chicago, IL, 10 University <strong>of</strong> Southern California, Los<br />

Angeles, CA, 11 Wake Forest University Baptist Medical Center,<br />

NC, 12 Wake Forest University Health Sciences, NC.<br />

1585. Association <strong>of</strong> Variants in the TNFAIP3 Region with Systemic<br />

Lupus Erythematosus in a Multi-Ethnic Study. Indra Adrianto 5 ,<br />

Christopher J. Lessard 8 , Kenneth M. Kaufman 9 , Juan-Manuel<br />

Anaya 12 , Marta E. Alarcón-Riquelme on Behalf <strong>of</strong> the BIOLUPUS<br />

and GENLES Networks 6 , Sang-Cheol Bae 1 , Elizabeth E. Brown<br />

for PROFILE 13 , Barry I. Freedman 18 , Gary S. Gilkeson 4 , Chaim<br />

O. Jacob 16 , Judith A. James 8 , Robert P. Kimberly 13 , Javier<br />

Martin 3 , Joan T. Merrill 8 , Timothy B. Niewold 15 , So-Yeon Park 1 ,<br />

Bernardo A. Pons-Estel 10 , Betty P. Tsao 14 , Timothy J. Vyse 2 , Carl<br />

D. Langefeld 19 , Mary B. Humphrey 11 , John B. Harley 17 , Kathy L.<br />

Moser 8 , Courtney G. Montgomery 7 and Patrick M. Gaffney 7 ,<br />

1<br />

Hanyang University, Seoul, Republic <strong>of</strong> Korea, 2 Imperial <strong>College</strong><br />

London, 3 Instituto de Parasitologia y Biomedicina López-<br />

Neyra, CSIC, Granada, Spain, 4 Medical University <strong>of</strong> South<br />

Carolina, 5 Oklahoma Medical Research Foundation, Oklahoma<br />

City, OK, 6 Oklahoma Medical Research Foundation; Center<br />

<strong>of</strong> Genomics and Oncological Research (GENyO), Granada,<br />

Spain, 7 Oklahoma Medical Research Foundation; Co-Senior<br />

Authors, 8 Oklahoma Medical Research Foundation; The<br />

University <strong>of</strong> Oklahoma Health Sciences Center, 9 Oklahoma<br />

Medical Research Foundation; The University <strong>of</strong> Oklahoma<br />

Health Sciences Center; Oklahoma City VA Medical Center,<br />

10<br />

Sanatorio Parque, Rosario, Argentina, 11 The University <strong>of</strong><br />

Oklahoma Health Sciences Center, 12 Universidad del Rosario,<br />

Colombia, 13 University <strong>of</strong> Alabama at Birmingham, 14 University<br />

<strong>of</strong> California, Los Angeles, 15 University <strong>of</strong> Chicago, 16 University <strong>of</strong><br />

Southern California Keck School <strong>of</strong> Medicine, 17 US Department<br />

<strong>of</strong> Veterans Affairs Medical Center; Cincinnati Children’s Hospital<br />

Medical Center, 18 Wake Forest University Baptist Medical Center,<br />

19<br />

Wake Forest University Health Sciences.<br />

1586. Association <strong>of</strong> Variants in the NF-kB Regulatory Pathway Loci<br />

with Systemic Lupus Erythematosus in Multiple Populations.<br />

Graham Wiley 6 , Indra Adrianto 8 , Jennifer A. Kelly 5 , Kenneth M.<br />

Kaufman 11 , Juan-Manuel Anaya 13 , Marta E. Alarcón-Riquelme<br />

on Behalf <strong>of</strong> the BIOLUPUS and GENLES Networks 7 , Sang-Cheol<br />

Bae 1 , So-Young Bang 1 , Elizabeth E. Brown for PROFILE 14 , Barry<br />

I. Freedman 19 , Gary S. Gilkeson 4 , Chaim O. Jacob 17 , Judith A.<br />

James 10 , Robert P. Kimberly 14 , Javier Martin 3 , Joan T. Merrill 10 ,<br />

Timothy B. Niewold 16 , Bernardo A. Pons-Estel 12 , Betty P. Tsao 15 ,<br />

Timothy J. Vyse 2 , Carl D. Langefeld 20 , John B. Harley 18 , Kathy L.<br />

Moser 10 , Courtney G. Montgomery 9 and Patrick M. Gaffney 9 ,<br />

1<br />

Hanyang University, Seoul, Republic <strong>of</strong> Korea, 2 Imperial <strong>College</strong><br />

London, 3 Instituto de Parasitologia y Biomedicina López-Neyra,<br />

CSIC, Granada, Spain, 4 Medical University <strong>of</strong> South Carolina,<br />

5<br />

Oklahoma Medical Research Foundation, 6 Oklahoma Medical<br />

Research Foundation, Oklahoma City, OK, 7 Oklahoma Medical<br />

Research Foundation; Center <strong>of</strong> Genomics and Oncological<br />

Research (GENyO), Granada, Spain, 8 Oklahoma Medical<br />

Research Foundation; Co-First Authors, 9 Oklahoma Medical<br />

Research Foundation; Co-Senior Authors, 10 Oklahoma Medical<br />

Research Foundation; The University <strong>of</strong> Oklahoma Health<br />

Sciences Center, 11 Oklahoma Medical Research Foundation;<br />

The University <strong>of</strong> Oklahoma Health Sciences Center; Oklahoma<br />

City VA Medical Center, 12 Sanatorio Parque, Rosario, Argentina,<br />

13<br />

Universidad del Rosario, Colombia, 14 University <strong>of</strong> Alabama at<br />

Birmingham, 15 University <strong>of</strong> California, Los Angeles, 16 University<br />

<strong>of</strong> Chicago, 17 University <strong>of</strong> Southern California Keck School <strong>of</strong><br />

Medicine, 18 US Department <strong>of</strong> Veterans Affairs Medical Center;<br />

Cincinnati Children’s Hospital Medical Center, 19 Wake Forest<br />

University Baptist Medical Center, 20 Wake Forest University<br />

Health Sciences.<br />

1587. Association Study <strong>of</strong> the ILAK1 Gene with Susceptibility to<br />

Systemic Lupus Erythematosus and Systemic Sclerosis. Yuko<br />

Ota 3 , Yasushi Kawaguchi 1 , Manabu Kawamoto 2 , Kae Takagi 2 ,<br />

Akiko Tochimoto 2 , Yasuhiro Katsumata 2 , Takahisa Gono 2 ,<br />

Sayumi Baba 2 , Yuko Okamoto 2 and Hisashi Yamanaka 4 , 1 Tokyo<br />

Women’s Medical Univ, Tokyo, Japan, 2 Tokyo Women’s Medical<br />

Univ, 3 Tokyo Women’s Medical University, Tokyo, Japan, 4 Tokyo<br />

Womens Med Univ, Shinjuku-ku, Tokyo, Japan.<br />

1588. Combining Genetic and Environmental Risk Factors To Model<br />

RA Susceptibility. Lori B. Chibnik 3 , Bo Ding 7 , Brendan T. Keenan 4 ,<br />

Katherine P. Liao 2 , Karen H. Costenbader 1 , Lars Klareskog 6 , Lars<br />

Alfredsson 7 and Elizabeth W. Karlson 5 , 1 Brigham & Women,<br />

Boston, MA, 2 Brigham & Women’s Hosp, Boston, MA, 3 Brigham<br />

and Women’s Hospital, Boston, MA, 4 Brigham and Women’s<br />

Hospital, 5 Brigham and Womens Hosp, Boston, MA, 6 Karolinska<br />

University Hospital, Stockholm, Sweden, 7 Karolinska University<br />

Hospital.<br />

2010 Program Book 241

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