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B O O K - American College of Rheumatology

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ACR/ARHP Poster Session B<br />

Seibold 13 , 1 Brigham & Womens Hospital, Boston, MA, 2 German<br />

Rheumatism Research Centre - Berlin, Berlin, Germany,<br />

3<br />

Institute <strong>of</strong> Clinical Pharmacology, Medical Faculty, University<br />

<strong>of</strong> Dresden, Dresden, Germany, 4 Louisiana State University<br />

Health Sciences Center - New Orleans, New Orleans, LA,<br />

5<br />

Mayo Clinic, Rochester, MN, 6 Medical University <strong>of</strong> Bialystok,<br />

Bialystok, Poland, 7 National Jewish Health, Denver, CO, 8 Royal<br />

Brompton Hospital and National Heart and Lung Institute,<br />

London, United Kingdom, 9 Royal Free Hospital, London, United<br />

Kingdom, 10 Stanford University; Palo Alto, Portola Valley, CA,<br />

11<br />

University Hospital Zurich, Zurich, Switzerland, 12 University<br />

<strong>of</strong> California Los Angeles, Los Angeles, CA, 13 University <strong>of</strong><br />

Connecticut Health Center, Farmington, CT, 14 University <strong>of</strong><br />

Michigan, Ann Arbor, MI, 15 University <strong>of</strong> Michigan, Ann Arbor,<br />

16<br />

University <strong>of</strong> Pittsburgh, Pittsburgh, PA.<br />

1213. Development <strong>of</strong> a Limited Scleroderma Cutaneous Activity and<br />

Damage Index. Lorinda Chung 1 , Daniel E. Furst 5 , Paul Maranian 3 ,<br />

Kait Arefiev 2 , Jeffrey Zwerner 2 , Dinesh Khanna 4 , Victoria P.<br />

Werth 6 and David Fiorentino 2 , 1 Stanford Univ Medical Center,<br />

Palo Alto, CA, 2 Stanford Univ Medical Center, 3 UCLA Medical<br />

School, 4 University <strong>of</strong> California Los Angeles, Los Angeles,<br />

CA, 5 University <strong>of</strong> California Los Angeles Medical School, Los<br />

Angeles, CA, 6 University <strong>of</strong> Pennsylvania, Philadelphia, PA.<br />

1214. Effect <strong>of</strong> Selective and Dual Endothelin Receptor Antagonists<br />

(ERAs) on SSc and Control Endothelial Cells Apoptosis.<br />

Yongqing Wang, Omar R. Kahaly and Bashar Kahaleh, University<br />

<strong>of</strong> Toledo, Toledo, OH.<br />

1215. Findings in Ocular Examination <strong>of</strong> Patients with Systemic<br />

Sclerosis. Niki Tsifetaki 3 , Charalampos Papagoras 3 , Contantinos<br />

A. Paschides 1 and Alexandros A. Drosos 2 , 1 Department <strong>of</strong><br />

Ophthalmology, Medical School, University <strong>of</strong> Ioannina,<br />

Ioannina, Greece, 2 Ioannina Medical School, Ioannina, Greece,<br />

3<br />

<strong>Rheumatology</strong> Clinic, Department <strong>of</strong> Internal Medicine,<br />

Medical School, University <strong>of</strong> Ioannina, Ioannina, Greece.<br />

1216. Genetic and Clinical Correlates <strong>of</strong> Anti-Fibrillarin (U3-RNP)<br />

Auto-Antibodies in African <strong>American</strong>s with Systemic Sclerosis.<br />

Roozbeh Sharif 2 , Marvin J. Fritzler 4 , John D. Reveille 3 , Shervin<br />

Assassi 1 , Maureen D. Mayes 5 and Frank C. Arnett 6 , 1 Univ <strong>of</strong><br />

Texas Health Science, Houston, TX, 2 Univ <strong>of</strong> Texas Health<br />

Science Center at Houston, Houston, TX, 3 Univ Texas Health Sci<br />

Ctr, Houston, TX, 4 University <strong>of</strong> Calgary, Calgary, AB, Canada,<br />

5<br />

University <strong>of</strong> Texas-Houston, Houston, TX, 6 UT Medical School,<br />

Houston, TX.<br />

1217. Impact <strong>of</strong> Systemic Sclerosis on Occupational and Pr<strong>of</strong>essional<br />

Activity with Attention to Patients with Digital Ulcers. Alice<br />

Berezne 3 , Raphaele Seror 2 , Sandrine Morell-Dubois 1 , Christelle<br />

Nguyen 4 , Eric Hachulla 1 , Loic Guillevin 4 and Luc Mouthon 4 ,<br />

1<br />

Service de Medecine Interne, Centre de Reference Pour la<br />

Sclerodermie Systemique, Hôpital Claude Huriez, Universite<br />

Lille 2 , Lille, France, Metropolitan, 2 Université Paris Descartes,<br />

Faculté de Médicine, Pôle de Médecine Interne, Centre de<br />

Reference Pour les Vascularites Necrosantes et la Sclerodermie<br />

Systemique, Hôpital Cochin, Assistance Publique-Hopitau,<br />

3<br />

Universite Paris Descartes, Faculte de Medicine, Pôle de<br />

Medecine Interne, Centre de Reference Pour les Vascularites<br />

Necrosantes et la Sclerodermie Systemique, Hôpital Cochin,<br />

Assistance Publique-Hôpitaux de Paris, Paris, Fra, 4 Universite<br />

Paris Descartes, Faculte de Medicine, Pole de Medecine Interne,<br />

Centre de Reference Pour les Vascularites Necrosantes et la<br />

Sclerodermie Systemique, Hopital Cochin, Assistance Publique-<br />

Hopitaux de Paris (AP-HP), Paris, France, Metro.<br />

1218. Is Surfactant D or CC-Chemokine Ligand 18 Biomarkers<br />

for Interstitial Lung Disease in Systemic Sclerosis? Shervin<br />

Assassi 2 , Julio Charles 3 , Frank C. Arnett 7 , Roozbeh Sharif 2 ,<br />

Robert E. Lasky 3 , Emilio B. Gonzalez 5 , Hilda T. Draeger 4 , Terry<br />

A. McNearney 1 , Sandeep K. Agarwal 2 , Ramana V. Gutala 3 , Rosa<br />

M. Estrada-Y-Martin 3 and Maureen D. Mayes 6 , 1 Eli Lilly and<br />

Co, Indianapolis, IN, 2 Univ <strong>of</strong> Texas Health Science Center at<br />

Houston, Houston, TX, 3 Univ <strong>of</strong> Texas Health Science Center at<br />

Houston, 4 Univ <strong>of</strong> Texas Health Science Center at San Antonio,<br />

San Antonio, TX, 5 Univ <strong>of</strong> Texas Medical Branch Galveston,<br />

Galveston, TX, 6 University <strong>of</strong> Texas-Houston, Houston, TX, 7 UT<br />

Medical School, Houston, TX.<br />

1219. Longitudinal Fatigue Severity Scale Scores Correlate with<br />

Modifiable Psychosocial Variables in Early Systemic Sclerosis.<br />

Astrud Lorraine Leyva 3 , Shervin Assassi 1 , Maureen D. Mayes 6 ,<br />

Deepthi K. Nair 1 , Michael Fischbach 2 , Roozbeh Sharif 1 , John D.<br />

Reveille 5 , Emilio B. Gonzalez 3 and Terry A. McNearney 4 , 1 Univ<br />

<strong>of</strong> Texas Health Science Center Houston, Houston, TX, 2 Univ <strong>of</strong><br />

Texas Health Science Center San Antonio, San Antonio, TX, 3 Univ<br />

<strong>of</strong> Texas Medical Branch, Galveston, TX, 4 Univ <strong>of</strong> Texas Medical<br />

Branch; Currently at Eli Lilly and Co, Indianapolis, IN, 5 Univ<br />

Texas Health Sci Ctr, Houston, TX, 6 University <strong>of</strong> Texas-Houston,<br />

Houston, TX.<br />

1220. Loss <strong>of</strong> Microvascular Response to Central Nervous Impulses<br />

to Finger Pulp in Systemic Sclerosis. Tone Kristin Bergersen 2 ,<br />

Anna-Maria H<strong>of</strong>fmann-Vold 1 , Oivind Midtvet 2 , Jan Tore Gran 2 ,<br />

Cato Mork 2 and Karin Toska 3 , 1 Oslo University Hospital, Oslo,<br />

PO Box 4950 Nydalen, Norway, 2 Oslo University Hospital, Oslo,<br />

Norway, 3 University <strong>of</strong> Oslo, PO Box 1103 Blindern, Norway.<br />

1221. Lower Education as a Proxy for Socioeconomic Status Is? Not<br />

Associated with Poor Outcomes in Systemic Sclerosis (SSc):<br />

Data from a Large SSc Cohort (Canadian Scleroderma Research<br />

Group). Samah Mansour 4 , Ashley Bonner 2 , Murray Baron 1 , Janet<br />

E. Pope 3 and The CSRG, 1 Jewish General Hospital, Montreal, QC,<br />

Canada, 2 McMaster University, 3 St Joseph Health Care London,<br />

London, ON, Canada, 4 University <strong>of</strong> Western Ontario.<br />

1222. Open Label Trial <strong>of</strong> Oral Treprostinil in Patients with Systemic<br />

Sclerosis and History <strong>of</strong> Digital Ulcers: Multiple Dose<br />

Pharmacokinetics and Tolerability. Elena Schiopu 6 , Laura K.<br />

Hummers 2 , Ami A. Shah 2 , Susan Walker 4 , Kristine Phillips 6 ,<br />

James R. Seibold 5 , Fredrick M. Wigley 1 and Kristan Rollins 3 ,<br />

1<br />

Johns Hopkins University, Baltimore, MD, 2 Johns Hopkins<br />

University, Baltimore, MD, 3 United Therapeutics, RTP, NC,<br />

4<br />

United Therapeutics, 5 University <strong>of</strong> Conneticut, Farmington, CT,<br />

6<br />

University <strong>of</strong> Michigan, Ann Arbor, MI.<br />

1223. Outcomes in a Newly Diagnosed Population <strong>of</strong> Connective<br />

Tissue Disease-Associated Pulmonary Arterial Hypertension<br />

Patients from the REVEAL Registry. Lorinda Chung 4 , Lori<br />

Parsons 1 , Paul M. Hassoun 2 , Michael McGoon 3 , David Badesch 6 ,<br />

Dave P. Miller 1 , Mark R. Nicolls 5 and Roham T. Zamanian 5 ,<br />

1<br />

ICON Clinical Research, 2 Johns Hopkins University, 3 Mayo<br />

Clinic, 4 Stanford Univ Medical Center, Palo Alto, CA, 5 Stanford<br />

University, 6 University <strong>of</strong> Colorado.<br />

1224. Patients with Systemic Sclerosis and Anti-Centromere<br />

Antibodies Are Affected with Accelerated Atherosclerosis.<br />

Annica Nordin 2 , Lena Björnådal 3 , Kerstin Jensen-Urstad 1<br />

and Elisabet Svenungsson 4 , 1 Dept. <strong>of</strong> Clinical Physiology,<br />

Södersjukhuset, Karolinska Institutet, Sweden, 2 Dept. <strong>of</strong><br />

Medicine, <strong>Rheumatology</strong> Unit, Karolinska Institutet, Stockholm,<br />

Sweden, 3 Dept. <strong>of</strong> Medicine, <strong>Rheumatology</strong> Unit, Karolinska<br />

Institutet, Sweden, Sweden, 4 Dept. <strong>of</strong> Medicine, <strong>Rheumatology</strong><br />

Unit, Karolinska Institutet, Sweden.<br />

224<br />

2010 Program Book

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