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B O O K - American College of Rheumatology

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ACR Poster Session A<br />

University <strong>of</strong> Melbourne, 5 John Hunter Hospital, Newcastle,<br />

Australia, 6 Menzies Research Institute, University <strong>of</strong> Tasmania,<br />

Hobart, Australia, 7 Monash Medical Centre, Melbourne,<br />

Australia, 8 Queen Elizabeth Hospital, Adelaide, Australia,<br />

9<br />

Royal Adelaide Hospital, Adelaide, Australia, 10 Royal North<br />

Shore Hospital, Sydney, Australia, 11 Royal Perth Hospital, Perth,<br />

Australia, 12 Royal Prince Alfred Hospital, Sydney, Australia, 13 St<br />

George Hospital, Sydney, Australia, 14 St Vincent’s Hospital,<br />

Melbourne, Australia, 15 Sunshine Coast <strong>Rheumatology</strong>,<br />

Australia.<br />

585. Pulmonary Artery Diameter Is Associated with Pulmonary<br />

Hypertension in Patients with Systemic Sclerosis (SSc).<br />

Elena Schiopu 4 , Ann J. Impens 4 , Barry H. Gross 3 , Fazleomar<br />

Mahmood 4 , James R. Seibold 1 and Kristine Phillips 2 , 1 University<br />

<strong>of</strong> Connecticut Health Center, Farmington, CT, 2 University <strong>of</strong><br />

Michigan, Ann Arbor, MI, 3 University <strong>of</strong> Michigan, Department<br />

<strong>of</strong> Radiology, Ann Arbor, MI, 4 University <strong>of</strong> Michigan,<br />

Scleroderma Program, Ann Arbor, MI.<br />

586. Pulmonary Hypertension Assessment and Recognition <strong>of</strong><br />

Outcomes in Scleroderma (PHAROS): Comparison <strong>of</strong> Outcomes<br />

in Subtypes <strong>of</strong> Pulmonary Hypertension. Robyn T. Domsic 6 ,<br />

Lorinda Chung 3 , Mardi Gomnberg-Maitland 4 , Jessica K. Gordon 2 ,<br />

Barbara M. Segal 5 , Virginia D. Steen 1 and PHAROS Investigators,<br />

1<br />

Gerogetown University Medical Center, Washington, DC,<br />

2<br />

Hospital for Special Surgery, New York, NY, 3 Stanford University<br />

Medical Center, Palo Alto, CA, 4 University <strong>of</strong> Chicago Medical<br />

Center, Chicago, IL, 5 University <strong>of</strong> Minnesota, Minneapolis, MN,<br />

6<br />

University <strong>of</strong> Pittsburgh, Pittsburgh, PA.<br />

587. Pulmonary Hypertension by Age <strong>of</strong> Scleroderma Onset and<br />

Subtype. Rebecca L. Manno 2 , Fredrick M. Wigley 1 and Laura K.<br />

Hummers 2 , 1 Johns Hopkins University, Baltimore, MD, 2 Johns<br />

Hopkins University, Baltimore, MD.<br />

588. Reproducibility <strong>of</strong> Semi-Automated Quantitative Nailfold<br />

Capillaroscopy Measurements in Patients with Systemic<br />

Sclerosis. Andrea K. Murray 4 , Tonia L. Moore 4 , Andy Vail 1 ,<br />

Joanne Manning 2 and Ariane L. Herrick 3 , 1 <strong>Rheumatology</strong><br />

Directorate, HealthMethodology Research Group, Manchester<br />

Academic Health ScienceCentre, The University <strong>of</strong><br />

Manchester, Salford Royal Hospital, Salford, UK, 2 Salford Royal<br />

NHSFoundation Trust, Salford, 3 The University <strong>of</strong> Manchester,<br />

Manchester Academic Health Science Centre, Manchester,<br />

Salford Royal Hospital, Salford, Greater Manchester, United<br />

Kingdom, 4 The University <strong>of</strong> Manchester, Manchester Academic<br />

Health Science Centre, Manchester, Salford Royal Hospital, UK.<br />

589. Risk Associated with African <strong>American</strong> Race in Relation<br />

to Prevalence <strong>of</strong> Cardinal Organ System Manifestations in<br />

Scleroderma. Elizabeth N. Le 3 , Rebecca L. Manno 3 , Laura K.<br />

Hummers 3 , Fredrick M. Wigley 2 and Allan C. Gelber 1 , 1 Baltimore,<br />

MD, 2 Johns Hopkins University, Baltimore, MD, 3 Johns Hopkins<br />

University, Baltimore, MD.<br />

590. Role <strong>of</strong> N-Terminal Pro-BNP in Detecting Clinically-Significant<br />

Cardiac Involvement in Systemic Sclerosis Patients. Cecilia<br />

Chighizola 3 , Benjamin Schreiber 2 , Pier Luigi Meroni 3 , Gerry<br />

Coghlan 1 , Christopher P. Denton 4 and Voon Ong 1 , 1 Center for<br />

<strong>Rheumatology</strong> and Connective Tissue Diseases, UCL Medical<br />

School, Royal Free Hospital, London, United Kingdom, 2 Center<br />

for <strong>Rheumatology</strong> and Connective Tissue Diseases, UCL Medical<br />

School, Royal Free Hospital, London, 3 <strong>Rheumatology</strong> Division,<br />

Department <strong>of</strong> Internal Medicine, Istituto G. Pini, University<br />

<strong>of</strong> Milan, Milan, Italy, 4 Royal Free Hospital, London, United<br />

Kingdom.<br />

591. Scleroderma Autoantibodies and Disease Subtype Predict<br />

Pulmonary Hypertension Classification in the PHAROS<br />

Registry. Monique E. Hinchcliff 5 , Aryeh Fischer 4 , Nadera Sweiss 6 ,<br />

Maureen Mayes 7 , Marcy Bolster 3 , Virginia Steen 1 and PHAROS<br />

Investigators 2 , 1 Georgetown University, 2 Gerogetwon University,<br />

3<br />

Medical University <strong>of</strong> South Carolina, 4 National Jewish Health,<br />

5<br />

Northwestern University, 6 University <strong>of</strong> Chicago, 7 University <strong>of</strong><br />

Texas-Houston Medical School.<br />

592. Scleroderma Lung Disease: Effect <strong>of</strong> Co-Existent Pulmonary<br />

Hypertension on Progression <strong>of</strong> Interstitial Lung Disease.<br />

Anupama Shahane, Joseph Parambil, Meng Xu and Soumya<br />

Chatterjee, Cleveland Clinic.<br />

593. Sildenafil Increases Vasodilation in Systemic Sclerosis: An<br />

Interim Analysis from a Single Centre Pilot Study. Silvia<br />

Bellando-Randone, Irene Miniati, Serena Guiducci, Maria Letizia<br />

Conforti, Jelena Blagojevic, Ginevra Fiori, Francesca Bartoli,<br />

Francesca Nacci and Marco Matucci-Cerinic, Department <strong>of</strong><br />

Biomedicine Section <strong>of</strong> <strong>Rheumatology</strong> University <strong>of</strong> Florence,<br />

Italy.<br />

594. Subclinical Atherosclerosis Is Increased in Systemic Sclerosis<br />

— A Case-Control Study. Karen M. Au 1 , Maureen A. McMahon 1 ,<br />

Daniel E. Furst 3 , Bevra H. Hahn 4 , Nagesh Ragavendra 1 , Amber<br />

Bechtel 1 , Lori Sahakian 1 and Dinesh Khanna 2 , 1 UCLA School <strong>of</strong><br />

Medicine, Los Angeles, CA, 2 University <strong>of</strong> California Los Angeles,<br />

Los Angeles, CA, 3 University <strong>of</strong> California Los Angeles Medical<br />

School, Los Angeles, CA, 4 University <strong>of</strong> California Los Angeles<br />

School <strong>of</strong> Medicine, Los Angeles, CA.<br />

595. Symptom Burden, Quality <strong>of</strong> Life and Attitudes toward<br />

Palliative Care in Patients with Pulmonary Hypertension with<br />

and without Systemic Sclerosis. Nicole M. Orzechowski 1 , Keith<br />

M. Swetz 2 , Tait D. Shanafelt 3 , Jeff A. Sloan 3 , Paul J. Novotny 3 ,<br />

Robert P. Frantz 3 and Michael D. McGoon 3 , 1 Dartmouth<br />

Hitchcock Med Center, Lebanon, NH, 2 Mayo Clinic, Rochester,<br />

MN, 3 Mayo Clinic.<br />

596. The Degree <strong>of</strong> Skin Involvement Predicts Distinct Interstitial<br />

Lung Disease Outcomes in Systemic Sclerosis. Tricia R. Cottrell,<br />

Fredrick Wigley, Robert Wise and Francesco Boin, Johns Hopkins<br />

University, Baltimore, MD.<br />

597. The Effect <strong>of</strong> Gastric Acid Suppression with Esomeprazole<br />

on Treprostinil Diethanolamine Pharmacokinetics in Healthy<br />

Volunteers. Kristan Rollins 2 , Susan Walker 2 , Jennifer Kates 2 ,<br />

Kevin Laliberte 2 and Allison Lim 1 , 1 United Therapetutics,<br />

Research Triangle Park, NC, 2 United Therapeutics.<br />

598. The Pulmonary Arterial Hypertension Quality Enhancement<br />

Research Initiative (PAH-QuERI): Comparing Baseline<br />

Characteristics, Management and Survival in Patients with<br />

Idiopathic PAH (IPAH) to Patients with Systemic Sclerosis<br />

Related PAH (SSc-PAH). Philip J. Clements 2 , Amparo Casanova 1 ,<br />

Tan Mary 1 , Channick Richard 4 , Valerie McLaughlin 6 , Ron Oudiz 2 ,<br />

Lew Rubin 5 , Tapson Victor 3 and Langer Anatoly 1 , 1 Canadian<br />

Heart Research Center, 2 David Geffen School <strong>of</strong> Medicine<br />

at UCLA, 3 Duke University Medical Center, Durham, NC,<br />

4<br />

Massachusetts General Hospital, 5 University <strong>of</strong> California at San<br />

Diego, 6 University <strong>of</strong> Michigan Health System.<br />

188<br />

2010 Program Book

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