B O O K - American College of Rheumatology

5:00 PM
2176. A Role of Autoimmune Response to M3 Muscarinic
Acethylcholine Receptor in the Pathogenesis of Sjögren’s
Syndrome Like Autoimmune Sialoadenitis.
Mana Iizuka 2 , Hiroto Tsuboi 2 , Yumi Nakamura 2 , Naomi Matsuo 2 ,
Isao Matsumoto 2 and Takayuki Sumida 1 , 1 Univ of Tsukuba/Inst
Clin Med, Tsukuba City, Japan, 2 Univ of Tsukuba/Inst Clin Med
5:15 PM
2177. Δ4BAFF, an Alternate-Splice Isoform That Acts as a
Transcription Factor To Enhance BAFF Production in Primary
Sjögren’s Syndrome.
Jacques-Olivier Pers, Gabriel J. Tobon, Laëtitia Le Pottier and
Pierre Youinou, Brest University, Brest, France
5:30 PM
2178. Local TACI-Ig Gene Therapy of the Salivary Gland of NOD
Mice Reduces Auto-Immune Inflammation by Affecting the B
Cell Compartment.
Nienke Roescher 2 , Jelle L. Vosters 2 , Marco Guadagnoli 2 , Jan
P. Medema 2 , Gabor G. Illei 4 , John A. Chiorini 3 and Paul P.
Tak 1 , 1 Academic Med Ctr/Univ of Amsterdam, Amsterdam,
The Netherlands, 2 Academic Medical Center-University of
Amsterdam, 3 National Insitutes of Health-National Institute
of Dental and Craniofacial Research, 4 NIDCR, NIH #10 1N114,
Bethesda, MD
5:45 PM
2179. EBV-mir-Bart13 Downregulates Stim1, a Protein Involved
in Calcium Signaling, in Human Salivary Gland Cells and May
Contribute to the Pathogenesis of Sjögren’s Syndrome.
Alessia Gallo 1 , Mayank Tandon 1 , Gabor G. Illei 2 and Ilias Alevizos 1 ,
1
National Insitutes of Health-National Institute of Dental and
Craniofacial Research, 2 NIDCR, NIH #10 1N114, Bethesda, MD
A311
Spondylarthropathies and Psoriatic Arthritis - Clinical
Aspects and Treatment - Biomarkers II
Moderators: Daniel O. Clegg, MD; University of Utah Medical
Center; Salt Lake City, UT
Robert Landewe, MD; University Hospital Maastricht;
Maastricht, The Netherlands
4:30 PM
2180. Striking Prevalence of Axial Spondyloarthritis in Primary
Care Patients with Chronic Low Back Pain; a Cross-Sectional
Study.
Lonneke van Hoeven 3 , Jolanda Luime 1 , Huub Han 2 and Angelique
Weel 4 , 1 Erasmus Medical Centre, 2 Maasstadziekenhuis,
3
Maasstadziekenhuis / Erasmus Medical Centre, Rotterdam, The
Netherlands, 4 Maasstadziekenhuis Rotterdam, Rotterdam, The
Netherlands
4:45 PM
2181. Screening for Axial Spondyloarthritis in a Primary Care:
Comparison of Two Strategies in a Multicenter Prospective
Study.
Denis Poddubnyy 1 , Janis Vahldiek 1 , Inge Spiller 1 , Beate Buss 1 ,
Martin Rudwaleit 1 and Joachim Sieper 2 , 1 Charité - Campus
Benjamin Franklin, Berlin, Germany, 2 Charite Campus Benjamin
Frankl, Berlin, Germany
5:00 PM
2182. Do the New EULAR/ACR Rheumatoid Arthritis
Classification Criteria Identify Early Psoriatic Arthritis Patients?
Laura C. Coates 2 , Philip G. Conaghan 2 , Paul Emery 2 , Michael J.
Green 3 , Gamal Ibrahim 1 , Helen MakIver 1 and Philip S. Helliwell 2 ,
1
Bradford Hospitals NHS Trust, UK, Bradford, United Kingdom,
2
LIMM, Section of Musculoskeletal Disease, University of Leeds,
Leeds, UK, 3 York Hospitals NHS Trust, York, UK
5:15 PM
2183. The CASPAR Criteria Can Be Used To Identify Early
Psoriatic Arthritis.
Laura C. Coates 2 , Philip G. Conaghan 3 , Paul Emery 3 , Michael J.
Green 4 , Gamal Ibrahim 1 , Helen MakIver 1 and Philip S. Helliwell 3 ,
1
Bradford Hospitals NHS Trust, UK, Bradford, United Kingdom,
2
LIMM, Section of Musculoskeletal Disease, University of Leeds,
Leeds, United Kingdom, 3 LIMM, Section of Musculoskeletal
Disease, University of Leeds, UK, 4 York Hospital NHS Trust, York,
UK
5:30 PM
2184. Supppression of Both DKK-1 and SOST in a Mouse
Model of Ankylosing Spondylitis Implicates the WNT-Signalling
Pathway in the Linkage of Inflammation and Bony Ankylosis in
Spondyloarthritis.
Gethin P. Thomas 2 , Ran Duan 3 , Allison Pettit 4 , Tibor Glant 1 and
Matthew A. Brown 2 , 1 Rush University Medical Center, 2 The
University of Queensland Diamantina Institute, 3 The University
of Queensland Diamantina Institute, 4 University of Queensland
Centre for Clinical Research
5:45 PM
2185. Genetic and Clinical Correlates in African Americans with
Ankylosing Spondylitis.
Shervin Assassi 4 , Julie T. Dang 3 , Michael M. Ward 2 , Joel D.
Taurog 6 , Michael H. Weisman 1 and John D. Reveille 5 , 1 Cedars-
Sinai Medical Center, Los Angeles, CA, 2 NIH, NIAMS, IRP,
Bethesda, MD, 3 Univ of Texas Health Science Center at Houston,
4
Univ of Texas Health Science Center at Houston, Houston, TX,
5
Univ Texas Health Sci Ctr, Houston, TX, 6 U-Texas SW Med Ctr,
Dallas, TX
A315
Systemic Lupus Erythematosus - Animal Models
Moderators: Philip L. Cohen, MD; Temple University;
Philadelphia, PA
Jane E. Salmon, MD; Hospital for Special Surgery; New York, NY
4:30 PM
2186. Neutrophil Gelatinase Associated Lipocalin (NGAL) and
Its Role in the Pathogenesis of Nephritis Induced by Pathogenic
Antibodies.
Rahul Pawar 4 , Simona Gindea 4 , Arlene T. Tieng 3 , MIlena
Pitashny 4 , Leal Herlitz 5 , Benjamin E. Levine 2 , Thorsten Berger 6 ,
Tak W. Mak 6 and Chaim Putterman 1 , 1 Albert Einstein College
of Med, Bronx, NY, 2 Albert Einstein College of Medicine,
Woodmere, NY, 3 Albert Einstein College of Medicine, Bronx, NY,
4
Albert Einstein College of Medicine, 5 Columbia-Presbyterian
School of Medicine, 6 The Campbell Family Institute for Breast
Cancer Research, Toronto, ON, Canada
wednesday
2010 Program Book 127