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B O O K - American College of Rheumatology

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wednesday<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• define the state <strong>of</strong> the evidence regarding physical activity in<br />

adults with arthritis living in rural communities<br />

• describe the development <strong>of</strong> a community-based approach<br />

to learn about the levels <strong>of</strong> physical activity in a rural<br />

environment in persons with arthritis<br />

• examine perceived barriers/facilitators <strong>of</strong> physical activity in<br />

persons with arthritis in rural communities<br />

• identify benefits <strong>of</strong> physical activity in this subpopulation<br />

B308<br />

Using Pharmacogenomics to Improve Therapy for<br />

Pediatric Patients P/C PS<br />

Moderator: Bernadette McNally, MS, PAC; University <strong>of</strong> Utah;<br />

Salt Lake City, UT<br />

Speaker: Mara L. Becker, MD; Children’s Mercy Hospital; Kansas<br />

City, MO<br />

Session Overview:<br />

In the emerging field <strong>of</strong> personalized medicine, it is important to<br />

recognize that there is significant variability in drug response and<br />

toxicity between adults and children. Targeted therapy-based on<br />

age, genetics and development <strong>of</strong> the child may be the future<br />

<strong>of</strong> prescribing medications for rheumatic disease for children,<br />

specifically methotrexate. Ontogeny, the normal developmental<br />

process may affect aspects <strong>of</strong> pharmacological response in<br />

children including drug absorption, distribution, metabolism and<br />

excretion. Developmental expression <strong>of</strong> different pathways at<br />

different times may lead to variability in medication response.<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• describe differences in disease expression and drug response<br />

in pediatric patients<br />

• define what makes children different, including developmental<br />

pharmacokinetics, pharmacogenetics in children and the role<br />

<strong>of</strong> ontogeny<br />

• summarize new pharmacogenomic data in commonly<br />

used medications in pediatrics and identify gaps in current<br />

knowledge<br />

ACR Meet the Pr<strong>of</strong>essor Sessions<br />

7:45 - 9:15 am<br />

Admission to each Meet the Pr<strong>of</strong>essor session requires a<br />

separate registration and ticket. To verify which session you<br />

registered for, check to make sure the registration code on your<br />

ticket matches the code listed below in parentheses.<br />

B207<br />

Adult Inflammatory Myopathy (061)<br />

Speaker: Mary E. Cronin, MD; Medical <strong>College</strong> <strong>of</strong> Wisconsin;<br />

Milwaukee, WI<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• discuss diagnostic pearls for the evaluation <strong>of</strong> someone<br />

suspected <strong>of</strong> having an inflammatory myopathy<br />

• discuss the treatment paradigm for inflammatory myopathies<br />

B208<br />

Crystal: Management <strong>of</strong> Gout (062) PS<br />

Speaker: Hyon K. Choi, MD, DrPH; University <strong>of</strong> British Columbia;<br />

Vancouver, BC, Canada<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• discuss the management <strong>of</strong> gout in patients with renal<br />

insufficiency or organ transplants<br />

• identify strategies to treat patients who are intolerant <strong>of</strong><br />

approved therapies<br />

• cite agents in development for the treatment <strong>of</strong><br />

hyperuricemia and gout<br />

B209<br />

Pediatrics: Spondyloarthritis in Children (063) P<br />

Speaker: Shirley Tse, MD; Hospital for Sick Children; Toronto, ON,<br />

Canada<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• describe differences between spondylarthritis in children and<br />

adults<br />

• discuss the approach to diagnosis and treatment <strong>of</strong> children<br />

with spondylarthritis<br />

B210<br />

Pregnancy in Rheumatic Diseases (064)<br />

Speaker: Megan E.B. Clowse, MD, MPH; Duke University Medical<br />

Center; Durham, NC<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• discuss the effects <strong>of</strong> pregnancy on the activity <strong>of</strong> rheumatic<br />

diseases<br />

• describe the challenging management issues unique to<br />

pregnancy<br />

B301<br />

Pulmonary Manifestations <strong>of</strong> Rheumatic Disease (065)<br />

Speaker: Paul F. Dellaripa, MD; Brigham and Women’s Hospital;<br />

Boston, MA<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• identify emerging concepts regarding the pathophysiology <strong>of</strong><br />

inflammation and fibrosis in autoimmune lung disease<br />

• determine the appropriate use <strong>of</strong> diagnostic tests in<br />

the evaluation <strong>of</strong> patients with rheumatic disorders and<br />

autoimmune lung disease<br />

• discuss the limits <strong>of</strong> traditional therapeutic options and<br />

possible emerging therapies in managing autoimmune lung<br />

disease<br />

B302<br />

Rheumatoid Arthritis: Biological Agents (066) PS<br />

Speaker: Larry W. Moreland, MD; University <strong>of</strong> Pittsburgh<br />

Medical Center; Pittsburgh, PA<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• identify biologic agents in use for the treatment <strong>of</strong> rheumatoid<br />

arthritis<br />

• describe the risk/benefit pr<strong>of</strong>iles <strong>of</strong> biologic agents<br />

• discuss the emerging biologics and their advantages for the<br />

therapeutic algorithm<br />

96<br />

2010 Program Book

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