B O O K - American College of Rheumatology
B O O K - American College of Rheumatology
B O O K - American College of Rheumatology
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ACR Poster Session A<br />
148<br />
Halls B1 & B2<br />
2010 Program Book<br />
MONDAY, NOVEMBER 8, 2010<br />
Antiphospholipid Syndrome<br />
1. Acquired Resistance to Activated Protein C Is a Feature <strong>of</strong> Both<br />
Systemic Lupus Erythematosus (SLE) and Antiphospholipid<br />
Syndrome (APS) and Is More Marked in Patients with SLE<br />
and APS. Denis Wahl 3 , Stéphane Zuily 4 , Agnès Brunette 2 ,<br />
Marie Prestat-Tilly 4 , Véronique Regnault 2 , Jean Devignes 1 and<br />
Thomas Lecompte 1 , 1 Biological Haematology Department,<br />
Nancy University Hospital, Vandoeuvre les Nancy, France,<br />
2<br />
INSERM U961, Nancy Université, Vandoeuvre les Nancy,<br />
France, 3 Vascular Medicine Unit, Vandoeuvre les Nancy, France,<br />
4<br />
Vascular Medicine Unit, Nancy University Hospital, Vandoeuvre<br />
les Nancy, France.<br />
2. AGTRL1 and PRKCH Are Genetic Risk Factors for<br />
Antiphospholipid Syndrome. Hisako Nakagawa 1 , Tetsuya<br />
Horita 2 , Toshio Odani 2 , Yuichiro Fujieda 2 , Masaru Kato 2 , Kotaro<br />
Otomo 2 , Yasuko Nakagawa 2 , Shinsuke Yasuda 2 , Tatsuya Atumi 2<br />
and Takao Koike 2 , 1 Department <strong>of</strong> Medicine II, Hokkaido<br />
University Graduate School <strong>of</strong> Medicine, Sapporo, Hokkaido,<br />
Japan, 2 Department <strong>of</strong> Medicine II, Hokkaido University<br />
Graduate School <strong>of</strong> Medicine.<br />
3. Anti-β2 Glycoprotein I Antibodies from Leprosy Patients Do<br />
Not Show Thrombogenic Effects in an In Vivo Animal Model.<br />
Ricardo Forastiero 2 , Marta Martinuzzo 2 , Mariano Vega-<br />
Ostertag 2 , Gabriela de Larranaga 2 and Silvia S. Pierangeli 1 , 1 Univ<br />
<strong>of</strong> TX Medical Branch, Galveston, TX, 2 Universidad Favaloro,<br />
Buenos Aires, Argentina.<br />
4. Antiphospholipid Antibodies in Children with Systemic<br />
Lupus Erythematosus – 18 Years <strong>of</strong> Clinical Experience<br />
from North India. Surjit Singh 2 , Jasmina Ahluwalia 1 , Shano<br />
Naseem 3 , Deepti Suri 2 and Amit Rawat 2 , 1 Department <strong>of</strong><br />
Hematology, Post Graduate Institute <strong>of</strong> Medical Education<br />
and Research, Chandigarh, India, 2 Division <strong>of</strong> Pediatric Allergy<br />
and Immunology, Advanced Pediatrics Centre, Post Graduate<br />
Institute <strong>of</strong> Medical Education and Research, Chandigarh, India,<br />
3<br />
Division <strong>of</strong> Pediatric Hematology, Advanced Pediatrics Centre,<br />
Post Graduate Institute <strong>of</strong> Medical Education and Research,<br />
Chandigarh, India.<br />
5. Antiphospholipid Score (aPL-S): A Comprehensive Predictive<br />
Marker <strong>of</strong> Developing Thrombosis in Autoimmune Diseases.<br />
Kotaro Otomo 1 , Tatsuya Atsumi 2 , Yuichiro Fujieda 3 , Masaru<br />
Kato 3 , Olga Amengual 3 , Tetsuya Horita 3 , Shinsuke Yasuda 3<br />
and Takao Koike 3 , 1 Hokkaido Graduate School <strong>of</strong> Medicine,<br />
Department <strong>of</strong> Medicine II, Sapporo, Hokkaido, Japan,<br />
2<br />
Hokkaido Graduate School <strong>of</strong> Medicine, Department <strong>of</strong><br />
Medicine II, Sapporo, Japan, 3 Hokkaido Graduate School <strong>of</strong><br />
Medicine, Department <strong>of</strong> Medicine II.<br />
6. Antiphospholipid Syndrome (APS) Clinical Research Task Force<br />
(CRTF) Report. Doruk Erkan 2 , Ronald Derksen 6 , Roger A. Levy 3 ,<br />
Samuel Machin 5 , Thomas Ortel 1 , Silvia S. Pierangeli 4 , Robert A.<br />
S. Roubey 7 , Michael D. Lockshin 2 and on Behalf <strong>of</strong> APS Clinical<br />
Research Task Force, 1 Duke University Health System, Durham,<br />
NC, 2 Hospital for Special Surgery, New York, New York, NY,<br />
3<br />
Univ Estado Do Rio de Janeiro, Rio de Janeiro, Brazil, 4 Univ <strong>of</strong><br />
TX Medical Branch, Galveston, TX, 5 University <strong>College</strong> London<br />
Hospitals, London, UK, 6 University Medical Centre, Utrecht,<br />
Netherlands, 7 University <strong>of</strong> North Carolina, Chapel Hill, NC.<br />
7. Decreased Fibrin Clot Porosity in Patients with Antifosfolipid<br />
Syndrome. Anna Vikerfors 2 , Aleksandra Antovic 1 , Elisabet<br />
Svenungsson 2 , Katarina Bremme 3 and Margareta Holmström 4 ,<br />
1<br />
Department <strong>of</strong> Clinical Sciences, Karolinska Institutet/Danderyd<br />
Hospital, Stockholm, Sweden, 2 Department <strong>of</strong> Medicine,<br />
<strong>Rheumatology</strong> Unit, Karolinska Institutet/Karolinska University<br />
Hospital, Stockholm, Sweden, 3 Department <strong>of</strong> Woman and<br />
Child Health, Division <strong>of</strong> Obstetrics and Gynaecology, Karolinska<br />
Institutet/Karolinska University Hospital, Stockholm, Sweden,<br />
4<br />
Hematology Division, Department <strong>of</strong> Medicine, Karolinska<br />
Institutet/Karolinska University Hospital, Stockholm, Sweden.<br />
8. Global Analyses <strong>of</strong> Antiphospholipid Antibodies That Impair<br />
Antithrombin Inactivation <strong>of</strong> Procoagulant Factors. Meifang<br />
Wu 2 , Jennifer M. Grossman 3 , John FitzGerald 2 , Bevra H. Hahn 4<br />
and Pojen P. Chen 1 , 1 UCLA Schl <strong>of</strong> Medicine, Los Angeles, CA,<br />
2<br />
UCLA School <strong>of</strong> Medicine, 3 University <strong>of</strong> California Los Angeles,<br />
Sherman Oaks, CA, 4 University <strong>of</strong> California Los Angeles School<br />
<strong>of</strong> Medicine, Los Angeles, CA.<br />
9. Influenza Vaccination Can Induce New Onset Anticardiolipins<br />
but Not β2-Glycoprotein-I Antibodies among Patients with<br />
Systemic Lupus Erythematosusβ. Evan Glenn Vista 3 , Sherry<br />
R. Crowe 3 , Amy B. Dedeke 3 , Jourdan R. Anderson 2 , Linda F.<br />
Thompson 3 , Gillian Air 4 and Judith A. James 1 , 1 Oklahoma Med<br />
Research Foundation, Oklahoma City, OK, 2 Oklahoma Medical<br />
Research Foundation, 3 Oklahoma Medical Research Foundation,<br />
Oklahoma City, OK, 4 University <strong>of</strong> Oklahoma Health Science<br />
Center, Oklahoma City, OK.<br />
10. Platelet Activation and Paradoxical Inhibition <strong>of</strong> ADP<br />
Induced Aggregation by Antiphospholipid Antibodies. Kenji<br />
Oku 4 , Tatsuya Atsumi 2 , Olga Amengual 3 , Masahiro Ieko 1 , Shin<br />
Furukawa 6 , Hirohiko Kitakawa 6 , Yuji Hori 6 , Kazuyoshi Nihei 6 ,<br />
Yuuichiro Fujieda 3 , Kotaro Otomo 5 , Masaru Kato 3 , Tetsuya<br />
Horita 3 , Shinsuke Yasuda 3 and Takao Koike 3 , 1 Health Sciences<br />
University <strong>of</strong> Hokkaido, 2 Hokkaido University Graduate School<br />
<strong>of</strong> Medicine Internal Medicine II, Sapporo, Japan, 3 Hokkaido<br />
University Graduate School <strong>of</strong> Medicine Internal Medicine II,<br />
4<br />
Hokkaido University Graduate School <strong>of</strong> Medicine Internal<br />
Medicine II, Kushiro Red Cross Hospital, Japan, 5 Hokkaido<br />
UniversityGraduate School <strong>of</strong> Medicine Internal Medicine II,<br />
6<br />
Kushiro Red Cross Hospital.<br />
11. Prevalence and Prognostic Significance <strong>of</strong> Thrombotic<br />
Microangiopathy in Rheumatologic Patients: Clinical and<br />
Immunological Associations. Spyros Aslanidis, Athina<br />
Pyrpasopoulou, Stella Douma, Areti Triantafyllou, Michail<br />
Doumas and Chrysanthos Zamboulis, 2nd Propedeutic Dept <strong>of</strong><br />
Internal Medicine, Hippokration Hospital, Thessaloniki, Greece.<br />
12. Prevalence <strong>of</strong> Antibodies to Prothrombin (PT) and<br />
Prothrombin/Phosphatidylserine (PS) in a Cohort <strong>of</strong> Lupus<br />
Anticoagulant (LAC) Positive Samples. R. Aguilar-Valenzuela 2 , J.<br />
Dlott 1 , U. Khan 2 , M. Belter 1 , E. Doan 2 , N. Gould 1 , A. Schleh 2 and<br />
S. Pierangeli 2 , 1 Quest Diagnostics, Chantilly, VA, 2 Univ <strong>of</strong> TX Med<br />
Branch, Galveston, TX.<br />
13. The Influence <strong>of</strong> Thrombovascular Events on the Quality<br />
<strong>of</strong> Life in APS and SLE Patients. Amaris K. Balitsky, Valentina<br />
Peeva, Jiandong Su, Erik Yeo, Carol Landolt-Marticorena, Dafna<br />
D. Gladman, Murray B. Urowitz and Paul R. Fortin, University<br />
<strong>of</strong> Toronto Antiphospholipid Clinic, Division <strong>of</strong> <strong>Rheumatology</strong>,<br />
Toronto Western Hospital.<br />
14. Utility <strong>of</strong> Anti-Phosphatidylserine/Prothrombin and IgA<br />
Antiphospholipid Assays in Antiphospholipid Syndrome.<br />
Ehtisham Akhter 3 , Walter L. Binder 2 , Zakera Shums 2 and<br />
Michelle A. Petri 1 , 1 Timonium, MD, 2 Inova Diagnostics Inc, San<br />
Diego, CA, 3 Johns Hopkins University, Baltimore, MD.